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South Africa urgently needs an antiretroviral pregnancy registry

With the dolutegravir roll-out around the corner, the time is now ripe for patients and activists to demand a prospective pregnancy registry for the whole of South Africa. Whether it is a new endeavour or piggy-backs on international efforts is a matter for debate, but it is the only way we can answer the question of dolutegravir’s safety with the minimum number of women being exposed to the drug. It’s the least that patients deserve.

Published
29 January 2019
From
Spotlight
Efavirenz in pregnancy is at least as safe as other antiretrovirals

An individual patient data analysis of almost 25,000 pregnancies in women living with HIV has found that the rate of birth defects following exposure to efavirenz was

Published
17 January 2019
By
Roger Pebody
Top 10 HIV Clinical Developments of 2018

It's the beginning of the end. Not in some apocalyptic way, but rather in how we think about the prevention and management of HIV.

Published
20 December 2018
From
The Body Pro
Babies born to mums with HIV face higher risks even though they’re HIV negative

HIV-uninfected children born to mothers with HIV are prone to infections that are more severe, are at almost two times greater risk of dying before their first birthday, and are more likely to be born prematurely than children born to mothers without HIV.

Published
29 November 2018
From
The Conversation
Hepatitis C increases the risk of premature delivery for pregnant women with HIV

Co-infection with hepatitis C greatly increases the risk of pre-term delivery for pregnant women with HIV, Polish researchers reported this week at the International Congress on Drug

Published
02 November 2018
By
Keith Alcorn
Neural tube defects and integrase inhibitors: studies show no further evidence of increased risk

No further evidence of an increased risk of infant neural tube defects related to the use of dolutegravir or other integrase inhibitors in early pregnancy has emerged

Published
30 October 2018
By
Keith Alcorn
Dolutegravir Use During Pregnancy: What Are the Risks?

Infectious Disease Advisor spoke to Rebecca M. Zash, MD, a co-investigator of the interim analysis by the Tsepamo Study in Botswana, which was published in the New England Journal of Medicine in July.

Published
22 October 2018
From
Infectious Disease Advisor
Efavirenz, but not dolutegravir, linked to neurological problems in children

Children born to HIV-positive women who take efavirenz (Sustiva or Stocrin, also a component of Atripla) during pregnancy are at greater risk of developing neurological disorders, some of

Published
11 October 2018
By
Liz Highleyman
Efavirenz in HIV-positive pregnant women, risk of neurological condition in children

Researchers found children of women whose ART regimen included efavirenz were 60 percent more likely to develop a neurological condition, such as microcephaly (small head), seizures (from a high fever or other cause) and eye abnormalities than children whose mothers took other ART medications.

Published
05 October 2018
From
IDSA press release
Developmental problems of children born to women with HIV linked to substance use and HIV, not antiretrovirals

Pre-term births and developmental problems in children born to mothers with HIV are associated with HIV infection, substance use and smoking, Canadian researchers have reported in

Published
11 September 2018
By
Keith Alcorn
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Community Consensus Statement on Access to HIV Treatment and its Use for Prevention

Together, we can make it happen

We can end HIV soon if people have equal access to HIV drugs as treatment and as PrEP, and have free choice over whether to take them.

Launched today, the Community Consensus Statement is a basic set of principles aimed at making sure that happens.

The Community Consensus Statement is a joint initiative of AVAC, EATG, MSMGF, GNP+, HIV i-Base, the International HIV/AIDS Alliance, ITPC and NAM/aidsmap
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This content was checked for accuracy at the time it was written. It may have been superseded by more recent developments. NAM recommends checking whether this is the most current information when making decisions that may affect your health.

NAM’s information is intended to support, rather than replace, consultation with a healthcare professional. Talk to your doctor or another member of your healthcare team for advice tailored to your situation.