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Analytical treatment interruptions: minimising the risks and maximising their scientific value

Recommendations for the safe and appropriate use of ‘analytical treatment interruptions’ have been developed by a group of HIV experts, including clinicians, patient advocates, bioethicists, social scientists and

Published
15 May 2019
By
Alain Volny-Anne
Monoclonal antibody may lead to long-term viral load reduction

An experimental monoclonal antibody called PGT121 led to viral suppression that lasted for up to six months in HIV-positive people who started with a low viral load,

Published
11 April 2019
By
Liz Highleyman
Attacking persistent HIV reservoirs via a ‘long noncoding’ RNA

As effective as antiretroviral drugs have been in the treatment of HIV, the virus can still hide out in the body in reservoirs that have proven exceedingly difficult to eradicate. Now researchers at Cornell University have found a new way to attack these HIV reservoirs, and it involves “long noncoding” RNAs (lncRNAs), which don’t produce proteins themselves but instead dial protein-producing genes up or down.

Published
26 March 2019
From
Fierce Biotech
Science Issues Concern About HIV Remission Monkey Study

The journal Science is warning readers that an article it published on a much-hyped potential HIV remission approach didn't include all the facts.

Published
22 March 2019
From
Medscape (requires free registration)
A Path to Curing H.I.V.

The Daily podcast: For only the second time since the start of a global epidemic, a person was reported this month to have been cured of H.I.V., the virus that causes AIDS. Scientists and activists had almost given up on reaching that milestone. Here’s a look at how we got to this point.

Published
21 March 2019
From
New York Times (audio)
Curing HIV just got more complicated. Can CRISPR help?

Antiretroviral (ARV) drugs have turned HIV infection from a death sentence to a chronic condition. In most people the drugs routinely tamp HIV levels so low that standard tests find no virus in blood samples. But inexplicably, in about 10% of infected people HIV remains easily detectable in the blood even though they take their daily pills and are not saddled with drug-resistant mutants of the virus.

Published
18 March 2019
From
Science
Italy's therapeutic AIDS vaccine shows drastic reduction of HIV virus reservoirs: study

Clinical trials of an Italian therapeutic vaccine against AIDS showed a drastic reduction of virus reservoirs in treated patients, Italian researchers said on Wednesday.

Published
14 March 2019
From
Xinhua
‘Gentler cure’ technique produces delay in viral rebound in some people taken off HIV therapy

Researchers have introduced genetic changes into human T-cells that make them virtually immune to HIV infection, and the viral load in HIV-positive people who are inoculated with

Published
12 March 2019
By
Gus Cairns
CROI 2019: Will the “Düsseldorf patient” make three — further propelling cure research?

Five years after a stem cell transplant with the same critical factor as those received by the Berlin patient and the London patient, and four months after stopping antiretroviral treatment, a Düsseldorf man remains virally suppressed

Published
12 March 2019
From
Science Speaks
Anthony Fauci: Physicians cured a man of HIV, but that's not our best shot at fighting AIDS

The Berlin and London patients give important insights for HIV researchers, and a cure for HIV is an aspiration we continue to pursue. But the end of the epidemic - the reduction of new HIV infections and HIV-related deaths to very low levels - is within our reach even without a cure.

Published
12 March 2019
From
Sydney Morning Herald
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Community Consensus Statement on Access to HIV Treatment and its Use for Prevention

Together, we can make it happen

We can end HIV soon if people have equal access to HIV drugs as treatment and as PrEP, and have free choice over whether to take them.

Launched today, the Community Consensus Statement is a basic set of principles aimed at making sure that happens.

The Community Consensus Statement is a joint initiative of AVAC, EATG, MSMGF, GNP+, HIV i-Base, the International HIV/AIDS Alliance, ITPC and NAM/aidsmap
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This content was checked for accuracy at the time it was written. It may have been superseded by more recent developments. NAM recommends checking whether this is the most current information when making decisions that may affect your health.

NAM’s information is intended to support, rather than replace, consultation with a healthcare professional. Talk to your doctor or another member of your healthcare team for advice tailored to your situation.