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Setting the Standard: New prevention trials in the era of oral PrEP

There’s a lot going on in the world of HIV prevention research right now. One key issue is how participants might access oral PrEP as part of HIV prevention trials. It may seem simple: trial participants have the right to the highest standard of HIV prevention and care as part of participation. But the ethics, trial design issues and the mechanisms by which interventions are provided as standard of care are quite complex. Opinions differ and politics abound.

Published
08 December 2017
From
AVAC
Johnson & Johnson and Partners Announce First Efficacy Study for Investigational Mosaic HIV-1 Preventive Vaccine

The new, large-scale study (HVTN 705/HPX2008), also known as “Imbokodo”, will evaluate whether the investigational Janssen vaccine regimen is safe and able to reduce the incidence of HIV infection among 2,600 women in sub-Saharan Africa.

Published
30 November 2017
From
Johnson & Johnson press release
Four big insights into HIV/AIDS that provide hope of finding a vaccine

African researchers have been performing cutting-edge research to contribute to addressing the HIV epidemic. The sub-Saharan African Network for TB/HIV Research Excellence has been at the forefront of this research and has provided some important insights into how the virus spreads as well as the immune mechanisms that enable some people to control the virus without antiretroviral drugs.

Published
24 November 2017
From
The Conversation
European Cure Review concentrates on HIV therapeutic vaccines

A cure for HIV would almost inevitably have to involve a vaccine to improve the body’s natural ability to control HIV, a seminar on European HIV cure

Published
16 November 2017
By
Gus Cairns
Durable end to the HIV/AIDS pandemic likely will require an HIV vaccine

Theoretically, effective global implementation of existing HIV treatment and prevention tools could end the HIV/AIDS pandemic. However, from a practical standpoint, ending the HIV/AIDS pandemic without a vaccine is unlikely, according to a new commentary from Anthony S. Fauci, M.D., director of the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health.

Published
10 October 2017
From
Eurekalert Medicine & Health
Why HPV Vaccination Rates Remain Low in Rural States

The problem the vaccine has faced is its link to a taboo in American culture: sexual activity among teenagers. Health-care providers are the biggest hurdle to getting more children vaccinated.

Published
11 September 2017
From
MIT Technology Review
Another HIV vaccine efficacy trial will start this year

A year ago, one of the biggest pieces of prevention news at the Durban International AIDS Conference was the announcement that a large HIV vaccine efficacy study

Published
26 July 2017
By
Gus Cairns
The 2017 Pipeline Report

Treatment Action Group (TAG) announces the launch of its annual research and development landscape analysis: The Pipeline Report: Drugs, Diagnostics, Vaccines, Preventive Technologies, Research Toward a Cure, and Immune-Based and Gene Therapies in Development.

Published
19 July 2017
From
Treatment Action Group
Immune system may keep body from neutralizing HIV-1 virus

Researchers at the University of Colorado Anschutz Medical Campus have discovered that a process protecting the body from autoimmune disease appears to prevent it from creating antibodies that can neutralize the HIV-1 virus, a finding that could possibly help lead to a vaccine that stimulates production of these antibodies.

Published
11 July 2017
From
Eurekalert Medicine & Health
First vaccine shows gonorrhoea protection

A vaccine has for the first time been shown to protect against gonorrhoea, scientists in New Zealand say. The vaccine, originally developed to stop an outbreak of meningitis B, was given to about a million adolescents in New Zealand between 2004 and 2006. Researchers at the University of Auckland analysed data from sexual health clinics and found gonorrhoea cases had fallen 31% in those vaccinated. The meachanism of protection is unknown. This particular vaccine is no longer available but the UK has been using a similar vaccine, though whether it will protect is also unknown.

Published
11 July 2017
From
BBC
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Community Consensus Statement on Access to HIV Treatment and its Use for Prevention

Together, we can make it happen

We can end HIV soon if people have equal access to HIV drugs as treatment and as PrEP, and have free choice over whether to take them.

Launched today, the Community Consensus Statement is a basic set of principles aimed at making sure that happens.

The Community Consensus Statement is a joint initiative of AVAC, EATG, MSMGF, GNP+, HIV i-Base, the International HIV/AIDS Alliance, ITPC and NAM/aidsmap
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This content was checked for accuracy at the time it was written. It may have been superseded by more recent developments. NAM recommends checking whether this is the most current information when making decisions that may affect your health.

NAM’s information is intended to support, rather than replace, consultation with a healthcare professional. Talk to your doctor or another member of your healthcare team for advice tailored to your situation.