aidsmap news: Black people and women are under represented in anti-HIV drug studies, 1 June 2020

News from aidsmap

Black people and women are under-represented in anti-HIV drug trials

Black people and women are under represented in anti-HIV drug studies

Recruitment to clinical trials that lead to the licensing of antiretroviral drugs is not representative of the global HIV pandemic, an international group of researchers report in the Journal of Virus Eradication. Licensing studies were overwhelmingly conducted in richer countries and white men were massively over-recruited.

Prevalence of Mycoplasma genitalium in gay men equals that of chlamydia

The prevalence of Mycoplasma genitalium – an STI that many people have never heard of – among gay and bisexual men is comparable to that of chlamydia, Australian researchers report in Sexually Transmitted Infections. Pooling the results of 46 international studies showed Mycoplasma genitalium infection rates of 5% in the urethra, 6% in the rectum and 1% in the throat. The prevalence was higher among men with STI symptoms and the rate of urethral infection was higher among HIV-positive men.

HIV 'morning-after pill' prescriptions have fallen sixfold during the lockdown

According to figures published in The Lancet HIV, prescriptions for HIV post-exposure prophlyaxis (PEP) at the largest HIV and sexual health clinic in Europe, 56 Dean Street in London, fell from an average of 40 a week in January, to seven a week in April, after lockdown for COVID-19 was instituted on 23 March.

Positive and motivational messages, not a focus on risk, needed for PrEP communications in South Africa

Young women in South Africa prefer demand-creation materials for PrEP that are empowering and motivational, according to a report from a project in a township near Cape Town, published in Gates Open Research. The multiple rounds of consultation with community members resulted in materials that did not focus on risk, prevention or even health. Instead, the campaign video emphasised young people’s control over their lives and being part of a generation that will end HIV.

Injectable antiretrovirals

Injectable antiretrovirals for HIV treatment or prevention: ambivalent views of potential users

A French study, recently published in AIDS Care, has explored perceptions of injectable long-acting antiretrovirals among potential users, that is, people living with HIV taking oral HIV treatment and users of HIV oral pre-exposure prophylaxis (PrEP). The study results demonstrate how complex the relationship of each individual to their HIV treatment or PrEP is in the real world.

Depression adversely affects cognitive function of people with HIV in both the short- and longer-term

Sustained depression is associated with long-term declines in cognitive function among people living with HIV, investigators from the United States report in the Journal of Acquired Immune Deficiency Syndromes. Executive functioning, recall and verbal fluency were all adversely affected by long-term depression. The study also showed that acute depression also had an impact on key aspects of cognitive function, including motor skills and speed of thought.

'I stopped PrEP and caught HIV': US researchers ask why

Individuals who stop PrEP may still remain at high risk of infection with HIV, according to research conducted in San Francisco and published in the Journal of the International AIDS Society. In-depth interviews with individuals who seroconverted to HIV after taking PrEP showed that major obstacles to remaining on it included drug use, mental health problems, housing insecurity, difficulty access the medication (expense, cost and time required for medical appointments), difficulty weighing up the risk and benefits of PrEP, and entering a committed relationship.

Amsterdam's strategy to detect and treat acute HIV dramatically reduces time to viral suppression

A strategy involving the targeted testing of gay and other men who have sex with men (MSM) for acute HIV infection is feasible and leads to immediate initiation of antiretroviral therapy (ART) and reduced time to viral suppression, investigators from Amsterdam report in Clinical Infectious Diseases. The proportion of acute HIV infections (of all new HIV diagnoses) increased from 0.6% to 11% after implementation of the strategy and the average time from diagnosis to viral suppression was almost halved.

Wanted: new writers for aidsmap

Wanted: new writers for aidsmap

We’re looking to recruit people to write for aidsmap as part of our Emerging Voices programme. Emerging Voices gives new writers the opportunity to gain experience and develop their skills and in a professional and supportive environment. Applications close on 14 June.

Editors' picks from other sources

Dr Anthony Fauci: How Larry Kramer "transformed the relationship" between activists and government | Time

I have known Larry Kramer, who died at 84 on 27 May, for more than 30 years. We had an extraordinary, complicated but wonderful relationship that ultimately culminated in a very deep friendship, affection and I would even say love for each other. He was unique in that he totally transformed the relationship between activism and the scientific, regulatory and government community.

The benevolent rage of Larry Kramer | The New Yorker

When the microphones were off and the crowds had gone home, Larry Kramer was a different person: sweet, thoughtful, and generous.

What the rift between the US and WHO means for global health | Nature

If President Trump sidelines the World Health Organization, experts foresee incoherence, inefficiency and resurgence of deadly diseases.

Canadian study provides damning evidence of the "dramatic overrepresentation" of Black men in HIV criminalisation news reporting | HIV Justice Network

A new study published this month by a group of leading Canadian social science academics provides damning evidence of the extraordinary overrepresentation of Black and Black immigrant male defendants in news reporting of Canadian HIV criminalisation cases.

HIV services take a backseat to COVID-19 in Russia | Inter Press Service

While health officials assured that quality care for those with HIV continues, as resources are stretched to keep the COVID-19 in check, those working with people living with HIV say they have experienced problems.

Weight gain and HIV treatment

Weight gain and HIV treatment

What causes weight gain after starting treatment? Who is most likely to gain weight? What drugs are associated with weight gain? Find out in our new research briefing.