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When an HIV-positive person is on effective treatment, a routine test known as a viral load test will often show that the virus is undetectable.

You may wonder, if the virus is undetectable in my blood, will I still test positive on an HIV test?

An HIV test is taken to see if someone is living with HIV. To do this, most HIV tests look in your blood for antibodies made in response to HIV rather than the HIV virus itself.

These HIV antibodies are produced by your body as part of its defence against HIV and can be found in the body a few weeks after HIV infection. These antibodies remain within the body even when the level of virus is low. Even if you are undetectable, there will still be some HIV hidden in some parts of the body, so you will usually test positive for HIV. To learn more about how HIV remains in your body, despite being undetectable in our blood please see here.

Glossary

HIV

Human immunodeficiency virus, the virus which causes AIDS. There are two variants: HIV-1, and HIV-2. HIV-1 is by far the most common worldwide. See ‘subtype’ for more information.

on

Abbreviation of a Latin term meaning every night.

undetectable viral load

A level of viral load that is too low to be picked up by the particular viral load test being used or below an agreed threshold (such as 50 copies/ml or 200 copies/ml). An undetectable viral load is the first goal of antiretroviral therapy.

viral load

Measurement of the amount of virus in a blood sample, reported as number of HIV RNA copies per milliliter of blood plasma. Viral load is an important indicator of HIV progression and of how well treatment is working. 

 
virus

A micro-organism composed of a piece of genetic material (RNA or DNA) surrounded by a protein coat. To replicate, a virus must infect a cell and direct its cellular machinery to produce new viruses.

 

In rare cases, antibody tests may return a false negative response due to low amounts of antibodies in the body. This result does not mean that HIV has been cured or removed. It just shows that the HIV test used wasn’t able to identify enough of the antibody due to the effectiveness of the HIV treatment.

If you were to stop taking HIV treatment, the amount of HIV in your blood would become detectable again because there are no longer HIV medications in your body to stop it.

For more information on HIV tests, and how they interact with HIV treatment, see here.

Beau Newham

Beau Newham

Article Author

Basic information

CD4 and viral load

CD4 and viral load

Undetectable viral load

Undetectable viral load

How treatment works

How treatment works

CD4 cell counts

A vial of blood is resting on a form that indicates it will be tested for CD4 cells. The image has a pink and purple filter over it.

CD4/CD8 ratio

A person wearing a blue surgical glove holds a vial of blood in front of a bloodwork form. The option "CD4 CD8" is checked. The image has a pink and purple filter over it.

Viral load

A close up of a person's arm while they are having their blood taken. The person taking the blood is wearing surgical gloves. We can see some of the blood is already in the tube.

What are logs in viral load results?

Vial of blood ready for viral load testing

Blood tests before starting or changing HIV treatment

A close up of a person's arm while they are having their blood taken. The person taking the blood is wearing surgical gloves. We can see some of the blood is already in the tube.

Blood monitoring for people with HIV

A person having a blood test. They are sitting in a chair while a nurse collects blood in a vial.

Are HIV tests accurate in people taking HIV treatment, PrEP or PEP?

A medication bottle on its side and open, with its contents of oval tablets spilling onto a white surface. The image has a pink and purple filter on it.