Salvage therapy workshop: full reports

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Two comprehensive reports from the International Salvage Therapy Workshop held last month in Chicago are now available on-line.

A report from Dr Steven Deeks is available at Medscape.com covering the following topics:

Glossary

salvage therapy

Any treatment regimen used after a number of earlier regimens have failed. People with HIV who have experienced side-effects and/or developed resistance to many HIV drugs receive salvage therapy, sometimes consisting of a large number of medications.

lactic acidosis

High blood levels of lactic acid, a substance involved in metabolism. Lactic acidosis is a rare side-effect of nucleoside analogues.

  • Multi-drug rescue therapy (mega-HAART)
  • Structured treatment interruptions
  • Pharmacokinetic enhancement of other protease inhibitors with ritonavir
  • Role of adherence in successful salvage therapy
  • Results from clinical trials of salvage regimens
  • Response to salvage therapy in the EuroSIDA cohort

In addition, a report by Dr Harvey Bartnof at HIVandhepatitis.com also covers the following topics:

  • Measuring lactic acid levels
  • Triple protease inhibitor combinations in salvage therapy
  • Responses to indinavir/ritonavir in patients with indinavir-related resistance mutations