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Integrase inhibitors

Raltegravir

Names: Raltegravir, Isentress 

Dose: One oval pink 400mg tablet twice daily. 

Tips on taking it: Take with or without food. 

Common side-effects: Diarrhoea, nausea and headache. 

Key drug interactions: Can affect blood levels of tipranavir/ritonavir and atazanavir/ritonavir, but it is not necessary to adjust drug doses because of this. Raltegravir should be dosed at 800mg twice daily when used with the TB drug rifampicin. 

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