Emtricitabine and tenofovir disoproxil fumarate combined in one pill. It may be marketed under the brand name Truvada, but generic versions are also available. It is taken in combination with other antiretroviral drugs.

You should not take emtricitabine/tenofovir disoproxil with any of the following drugs: tenofovir alafenamide, lamivudine, adefovir dipivoxil.

It is important your doctor knows about any other drugs you are taking in case they increase your risk of kidney problems. This includes creatine supplements used to increase exercise performance, as they can interfere with the results of kidney function blood tests.

Tell your doctor if you are taking any of the following drugs: aminoglycosides (for bacterial infection); amphotericin B (for fungal infection); foscarnet (for viral infection); ganciclovir (for viral infection); pentamidine (for infections); vancomycin (for bacterial infection); interleukin-2 (to treat cancer); cidofovir (for viral infection); non-steroidal anti-inflammatory drugs (NSAIDs, to relieve bone or muscle pains).

Kidney failure, lactic acidosis (too much lactic acid in the blood), bone thinning, pancreatitis.

Nausea, vomiting, diarrhoea, insomnia, abnormal dreams, headache, dizziness, allergic (hypersensitivity) reaction, rash, itching, weakness, abdominal pain, fatigue, bloating, flatulence, heartburn, raised blood sugar, pancreatic enzyme and triglyceride levels, raised liver enzyme or creatine kinase levels, low blood phosphate levels, skin darkening, low white blood cell count.

Best taken with food, but can be taken on an empty stomach.

Combination tablet of 200mg emtricitabine and 245mg tenofovir disoproxil (both NRTIs). The usual adult dose is one tablet taken once a day.  It is available as a generic drug so appearances will vary.