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SIRTURO® (bedaquiline) Receives Conditional Approval in the European Union for the Treatment of Multi-Drug Resistant Tuberculosis

Janssen-Cilag International NV (Janssen) announced today that the European Commission (EC) has granted conditional approval to SIRTURO® (bedaquiline) in the European Union, for use as part of an appropriate combination regimen for pulmonary multi-drug resistant tuberculosis (MDR-TB) in adult patients, when an effective treatment regimen cannot otherwise be composed for reasons of resistance or tolerability.

Published
07 March 2014
From
Janssen press release
CROI 2014: GeneXpert real world study yields mixed results, highlights SA health system challenges

Gavin Churchyard and Katherine Fielding presented results this morning from the XPert for TB: Evaluating a New Diagnostic Trial (EXTEND) on the question of whether Xpert MTB/RIF diagnostic test reduces early mortality in adults with suspected TB, facilitates earlier initiation of TB treatment and antiretroviral therapy and reduces the number of patients

Published
05 March 2014
From
Science Speaks
TB-HIV news from the 44th Union World Conference on Lung Health.

This edition of HATIP reports on the 44th Union World Conference on Lung Health, held in Paris, 30 October-3 November 2013.

Published
28 February 2014
From
HIV & AIDS treatment in practice
South African healthcare workers face greater risk for TB, HIV

A large-scale survey of South African healthcare workers has revealed major gaps in workplace protection against tuberculosis, HIV and hepatitis.

Published
17 February 2014
From
Science Daily
HIV associated with increased risk of MDR-TB

HIV infection is associated with an increased risk of multi-drug-resistant tuberculosis (MDR-TB), results of a systematic review and meta-analysis published in PLOS ONE show. HIV increased the

Published
05 February 2014
By
Michael Carter
GeneXpert use still hobbled by high pricing, Treatment Action Group, TB Community Advisory Board say

Letter to Cepheid cites continued cost of machines, Russia, China cartridge costs of five to six times negotiated price, and more.

Published
28 January 2014
From
Science Speaks
Russia's drug-resistant TB spreading more easily

Bacterial 'superbugs' are getting ever more potent. Tuberculosis (TB) strains in Russia carry mutations that not only make them resistant to antibiotics but also help them to spread more effectively, according to an analysis of 1,000 genomes from different TB isolates — one of the largest whole-genome study of a single bacterial species so far.

Published
28 January 2014
From
Nature
Major South African Trial Did Not Improve Tuberculosis Control in Gold Mines

A major trial aiming to cut the rate of tuberculosis among South Africa's gold miners did not reduce the number of cases or deaths from the disease, according to a study.

Published
27 January 2014
From
Science Daily
GLOBAL: Xpert MTB/RIF Test Quickly Detects TB and Resistance to Rifampicin

News-Medical.net reported on a second systematic review of the Xpert® MTB/RIF TB test, which is endorsed by the World Health Organization (WHO). WHO commissioned this updated Cochrane Review as part of the process to update the policy on the use of the test.

Published
23 January 2014
From
CDC National Prevention Information Network
Cotrimoxazole prophylaxis neither reduces TB risk nor complicates TB diagnosis in people with HIV

Cotrimoxazole prophylaxis has no impact on incidence or detection of tuberculosis (TB) in people with HIV, a study published PLoS One shows. The prospective, observational study involved

Published
21 January 2014
By
Michael Carter

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