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GeneXpert use still hobbled by high pricing, Treatment Action Group, TB Community Advisory Board say

Letter to Cepheid cites continued cost of machines, Russia, China cartridge costs of five to six times negotiated price, and more.

Published
28 January 2014
From
Science Speaks
Russia's drug-resistant TB spreading more easily

Bacterial 'superbugs' are getting ever more potent. Tuberculosis (TB) strains in Russia carry mutations that not only make them resistant to antibiotics but also help them to spread more effectively, according to an analysis of 1,000 genomes from different TB isolates — one of the largest whole-genome study of a single bacterial species so far.

Published
28 January 2014
From
Nature
Major South African Trial Did Not Improve Tuberculosis Control in Gold Mines

A major trial aiming to cut the rate of tuberculosis among South Africa's gold miners did not reduce the number of cases or deaths from the disease, according to a study.

Published
27 January 2014
From
Science Daily
GLOBAL: Xpert MTB/RIF Test Quickly Detects TB and Resistance to Rifampicin

News-Medical.net reported on a second systematic review of the Xpert® MTB/RIF TB test, which is endorsed by the World Health Organization (WHO). WHO commissioned this updated Cochrane Review as part of the process to update the policy on the use of the test.

Published
23 January 2014
From
CDC National Prevention Information Network
Cotrimoxazole prophylaxis neither reduces TB risk nor complicates TB diagnosis in people with HIV

Cotrimoxazole prophylaxis has no impact on incidence or detection of tuberculosis (TB) in people with HIV, a study published PLoS One shows. The prospective, observational study involved

Published
21 January 2014
By
Michael Carter
Hospitals may be discharging XDR-TB patients too soon – study

A shortage of beds may be forcing hospitals to discharge patients with extensively drug-resistant tuberculosis (XDR-TB) before they are cured and a minority may be unwittingly infecting others, according to new research by Cape Town and Stellenbosch universities.

Published
17 January 2014
From
Health-e
Immune suppression associated with reduced risk of TB transmission to household contacts of people with HIV/TB co-infection

HIV-related immune suppression is associated with a reduced risk of tuberculosis (TB) transmission to household contacts, according to research published in the online edition of Clinical Infectious Diseases. Researchers

Published
14 January 2014
By
Michael Carter
Bone marrow stem cells could defeat drug-resistant tuberculosis

In a study in The Lancet medical journal on Thursday, researchers said more than half of 30 drug-resistant TB patients treated with a transfusion of their own bone marrow stem cells were cured of the disease after six months.

Published
09 January 2014
From
Reuters
TB/HIV programmatic challenges highlighted at ICASA

The presence of tuberculosis (TB) at the initiation of antiretroviral therapy (ART) predicts retention in care, according to a study presented by Dr Enegela at the 17th

Published
07 January 2014
By
Lesley Odendal
European Medicines Agency recommends approval of a new medicine for multidrug-resistant tuberculosis

The European Medicines Agency's Committee for Medicinal Products for Human Use (CHMP) has recommended granting a conditional marketing authorisation for Sirturo (bedaquiline) for use as part of a combination therapy for pulmonary multidrug-resistant tuberculosis in adult patients when an effective treatment regimen cannot otherwise be composed for reasons of resistance or tolerability.

Published
24 December 2013
From
European Medicines Agency

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