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Treatment interruptions news

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Is It Ethical to Take People Off HIV Meds for Cure Research?

Cure studies typically require a temporary break in HIV treatment, often with little promise of a personal benefit to the participant.

Published
13 September 2017
From
Poz
VRC01 antibody can delay but not prevent viral rebound after interruption of early treatment

A broadly neutralising antibody modestly delayed the resurgence of viral replication following interruption of antiretroviral therapy (ART) started during very early infection, but all study participants ultimately experienced

Published
02 August 2017
By
Liz Highleyman
Researchers report case of bone marrow transplant patient off ART for 288 days without HIV rebound

An HIV-positive bone marrow transplant recipient at the Mayo Clinic experienced prolonged viral remission lasting nearly 10 months – longer than the so-called Boston patients – after interrupting

Published
06 March 2017
By
Liz Highleyman
Fast Rebound After Treatment Interruption in 9 of 10 With Low HIV DNA Reservoir

Nine of 10 people with a cell-associated HIV DNA level below 100 copies/106 cells had an HIV RNA rebound within 12 weeks after antiretroviral therapy interruption. The 10th person maintained HIV RNA control without drugs for more than 48 weeks, according to a study published in AIDS.

Published
13 June 2016
From
The Body PRO
VRC01 antibody delays but does not prevent HIV rebound after antiretroviral treatment interruption

VRC01, a broadly neutralising antibody targeting HIV's CD4 binding site, was able to modestly delay the return of viral replication following interruption of antiretroviral therapy (ART), according to

Published
08 April 2016
By
Liz Highleyman
People taking a large number of non-HIV-related medications more likely to stop or change HIV drugs

HIV-positive patients who are taking a large number of medications for the treatment of non-HIV-related conditions are at increased risk of stopping or changing their antiretroviral therapy (ART),

Published
27 January 2016
By
Michael Carter
Post-treatment control of HIV appears rare, biomarkers may help predict viral rebound

Only four individuals out of nearly 5000 people receiving care at US military health facilities were found to exhibit immune control of HIV after starting antiretroviral therapy

Published
04 November 2015
By
Liz Highleyman
Benefits of early HIV treatment are clear, but issues raised by START and D:A:D remain unresolved

The long-running controversy over when to start antiretroviral therapy (ART) has been definitively answered, but research is still needed to fully understand the implications of the large START

Published
23 October 2015
By
Liz Highleyman
Young woman stays undetectable for twelve years off treatment after early HIV therapy

The 8th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention (IAS 2015) heard today of a case where a young woman, who was infected with

Published
21 July 2015
By
Gus Cairns
Markers of Immune Exhaustion Predict Post-Treatment Control in HIV Patients

Biomarkers of immune exhaustion were associated with how long a patient was able to control HIV after treatment was interrupted, according to a study presented at CROI 2015.

Published
05 March 2015
From
The Body
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Community Consensus Statement on Access to HIV Treatment and its Use for Prevention

Together, we can make it happen

We can end HIV soon if people have equal access to HIV drugs as treatment and as PrEP, and have free choice over whether to take them.

Launched today, the Community Consensus Statement is a basic set of principles aimed at making sure that happens.

The Community Consensus Statement is a joint initiative of AVAC, EATG, MSMGF, GNP+, HIV i-Base, the International HIV/AIDS Alliance, ITPC and NAM/aidsmap
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This content was checked for accuracy at the time it was written. It may have been superseded by more recent developments. NAM recommends checking whether this is the most current information when making decisions that may affect your health.

NAM’s information is intended to support, rather than replace, consultation with a healthcare professional. Talk to your doctor or another member of your healthcare team for advice tailored to your situation.