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Last Gift Study: Community Perspective on End-of-Life HIV Research

In the second of this 3-part series, Sara Gianella Weibel, MD, on behalf of Infectious Disease Advisor, talks with Jeff Taylor, community activist and long-term HIV survivor, about ethical concerns and practical barriers in end-of-life research and how the HIV community will embrace this type of research.

Published
21 June 2017
From
Infectious Disease Advisor
Last Gift Study: End-of-Life HIV Research

Few opportunities currently exist for terminally ill people to participate in HIV research as a result of various cultural taboos and ethical concerns, such as exploitation, vulnerability, and coercion. However, when faced with their approaching death, some individuals may be willing to participate in research that offers no hope for their condition to leave a final gift to their community.

Published
21 June 2017
From
Infectious Disease Advisor
Understanding HIV's persistence

A new study, published in the Journal of Clinical Investigation, led by Mathias Lichterfeld, MD, PhD, and Guinevere Lee, PhD, from the Brigham and Women's Hospital Infectious Disease Division sheds new light on the mechanism underlying the persistence of HIV-1 infected cells despite antiviral treatment. "Our research points to a driving force that stabilizes the pool of HIV-infected cells in the host, which can persist lifelong despite very effective antiretroviral therapy," said Lichterfeld.

Published
20 June 2017
From
EurekAlert (press release)
New test detects latent HIV more accurately, moves closer to cure

Researchers at the University of Pittsburgh have come up with a more cost- and time-effective test that detects 'hidden' HIV more accurately.

Published
30 May 2017
From
HIV / AIDS News From Medical News Today
This Small Anti-Viral Pill Might Lead to an HIV Cure

For the first time, scientists have shown it’s possible to reduce HIV reservoirs in people living with HIV, thanks to a tiny anti-viral molecule (ABX464) patented by the biotechnology company Abivax.

Published
11 May 2017
From
HIVPlusMag
CRISPR Eliminates HIV in Live Animals

New data released from a research team led by investigators at the Lewis Katz School of Medicine at Temple University (LKSOM) and the University of Pittsburgh shows that HIV DNA can be excised from the genomes of living animals to eliminate further infection. Additionally, the researchers are the first to perform this feat in three different animal models, including a "humanized" model in which mice were transplanted with human immune cells and infected with the virus

Published
02 May 2017
From
Genetic Engineering & Biotechnology News
Defective HIV proviruses hinder immune system response and cure

HIV proviruses can outnumber functional HIV 1000 copies to one and the faulty proteins they create can complicate efforts to measure a patient's viral load, exhaust immune systems, shield functional HIV from attack by natural means or drugs, and seriously complicate the development of a cure.

Published
19 April 2017
From
Science Daily
Biomarker Opens New Door in HIV Cure Research

For the first time, investigators have found a biomarker that identifies some cells latently infected with HIV.

Published
14 April 2017
From
MedPage Today HIV/AIDS
We asked a scientist to explain CRISPR to us—and how it’s being used in HIV research

Perhaps you’ve heard about a research technology called CRISPR (pronounced “crisper”) in the news. Since the technology was first developed, it has generated headlines as thousands of researchers have adopted this technology as a way to edit the genes of plant, animal and human cells.

Published
12 April 2017
From
BETA blog
Research helps explain how vedolizumab antibody therapy leads to sustained viral remission

HIV and its monkey cousin SIV can carry the alpha-4 beta-7 integrin receptor in their outer envelope, which helps the virus enter gut cells during early infection,

Published
23 March 2017
By
Liz Highleyman
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Community Consensus Statement on Access to HIV Treatment and its Use for Prevention

Together, we can make it happen

We can end HIV soon if people have equal access to HIV drugs as treatment and as PrEP, and have free choice over whether to take them.

Launched today, the Community Consensus Statement is a basic set of principles aimed at making sure that happens.

The Community Consensus Statement is a joint initiative of AVAC, EATG, MSMGF, GNP+, HIV i-Base, the International HIV/AIDS Alliance, ITPC and NAM/aidsmap
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This content was checked for accuracy at the time it was written. It may have been superseded by more recent developments. NAM recommends checking whether this is the most current information when making decisions that may affect your health.

NAM’s information is intended to support, rather than replace, consultation with a healthcare professional. Talk to your doctor or another member of your healthcare team for advice tailored to your situation.