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Adenosine deaminase may help the immune system fight HIV on its own

New research published in the Journal of Leukocyte Biology suggests that adenosine deaminase enhances anti-HIV-1 specific immune responses by reducing the action of cells that impede HIV-specific defenses

Published
03 February 2016
From
Eurekalert Medicine & Health
HIV protein manipulates hundreds of human genes to advance progression into AIDS, study shows

“Our study indicates that this small viral protein, Tat, directly binds to about 400 human genes to generate an environment in which HIV can thrive. Then, this protein precisely turns off the body’s immune defense. It is striking that such a small viral protein has such a large impact,” Dr. D’Orso said.

Published
28 January 2016
From
UT Southwestern Medical Center
Study: HIV can hide and grow in 'sanctuaries' in body after it's undetectable in blood

The latest study appears to show a different type of "sanctuary," as the researchers called it, harboring cells with low levels of HIV replication that move into the blood. This suggests that virus growth could occur in a place where drug concentrations are very low.

Published
28 January 2016
From
Washington Post
Experimental Combination Surprises with Anti-HIV Effectiveness

A compound developed to protect the nervous system from HIV surprised researchers by augmenting the effectiveness of an investigational antiretroviral drug beyond anything expected. The potency of the combination treatment, tested so far in mice, suggests that it would be possible to rid the body of HIV for months, reducing the frequency with which patients must take these medications from daily to several times a year.

Published
27 January 2016
From
National Institute of Mental Health
I Watched Charlie Sheen on The Dr. Oz Show So You Don't Have To

I am dismayed to report that Tiger Blood Charlie is back and he has gone rogue. And his Chasing the Cure! conversation with Dr. Oz might be the worst thing to ever happen to AIDS cure research, or at least the most irresponsible reporting about it.

Published
14 January 2016
From
Poz
New amfAR/UCSF Institute Aims to Advance Basic Science of HIV Cure Research

The new institute will focus on 4 key areas: learning how latent viral reservoir are formed and persist in the body, determining the precise locations of these reservoirs, quantifying the amount of virus in them, and eradicating the reservoirs from the body.

Published
13 January 2016
From
HIVandhepatitis.com
$4.2M Grant to 'Kick and Kill' Latent HIV Using New Class of Meds

Tulane researchers will also test a gene editing strategy that delivers therapy tailored to each individual’s immune system.

Published
29 December 2015
From
Poz magazine news
HIV Antibody Infusion Safely Suppresses Virus in Infected People

A single infusion of a powerful antibody called VRC01 can suppress the level of HIV in the blood of infected people who are not taking antiretroviral therapy (ART), scientists at the National Institutes of Health report in a paper published today.

Published
24 December 2015
From
National Institute of Allergy and Infectious Diseases (NIAID)
Scientists reveal new phase of HIV infection

A new life cycle stage in HIV infection has been identified thanks to a novel technique they developed to take images of intact infected cells. Researchers have shown that this phase of infection, dubbed intra-nuclear migration, relies on the human protein CPSF6 to guide the virus through the host cell's nucleus and position it at active genes where it prefers to make its home.

Published
19 December 2015
From
Science Daily
NIH drops special 10% set-aside for AIDS research

In a major shakeup for the HIV/AIDS research community, the National Institutes of Health (NIH) today announced it will no longer support setting aside a fixed 10% of its budget—or $3 billion this year—to fund research on the disease. The agency also plans to reprogram $65 million of its AIDS research grant funding this year to focus more sharply on ending the epidemic.

Published
15 December 2015
From
Science
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