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Markers of Immune Exhaustion Predict Post-Treatment Control in HIV Patients

Biomarkers of immune exhaustion were associated with how long a patient was able to control HIV after treatment was interrupted, according to a study presented at CROI 2015.

Published
3 hours ago
From
The Body
Study of potential HIV 'cure' wins FDA nod

The trial at the City of Hope medical center will take blood-producing stem cells from patients infected with HIV and use a kind of molecular scissors — enzymes called zinc finger nucleases — to edit a protein that the virus uses to infect cells. The method was developed by Richmond's Sangamo BioSciences Inc.

Published
04 March 2015
From
San Francisco Business Times
Doctor who cured ‘Berlin patient’ of HIV: ‘We knew we were doing something very special’

Dr. Gero Hütter and Timothy Ray Brown speak about the transplant that forever linked them in medical history.

Published
02 March 2015
From
Fred Hutch News
New clues about viral rebound in Mississippi child thought cured of HIV

Clinicians involved in the care of a child many once hoped was cured of HIV have published details about the case in the New England Journal of Medicine. The authors found that the virus that eventually returned after the girl had been off antiretroviral therapy for more than 2 years was identical to her mother's viral strain. The case shows that HIV establishes a viral reservoir very soon after infection. Starting antiretroviral treatment a day after birth was not enough to prevent viral rebound, though it did appear to allow prolonged remission.

Published
23 February 2015
From
HIVandHepatitis.com
Biologist's Work on 'Viral Reservoirs' May Have Impact on AIDS/HIV

A drug used to treat patients with multiple sclerosis and Crohn’s disease has confirmed how “viral reservoirs” form in patients living with HIV and AIDS and also proven effective in animal trials at blocking the pathways to those reservoirs in the brain and gut, according to new research conducted by Professor of Biology Ken Williams and colleagues from other universities.

Published
19 February 2015
From
Boston College Chronicle
The Search for a Permanent Alternative to HIV Drugs

Researchers Carefully Tailor a Study to Find Patients to Test Going Off Antiretroviral Medication

Published
16 February 2015
From
Wall Street Journal
New HIV Gene Therapy Shows Promise in Mice

Researchers were able to replicate the functional cure of HIV that was seen in the "Berlin patient" in a mouse model, according to a study conducted at the University of California, Davis.

Published
14 January 2015
From
The Body Pro
I Am the Berlin Patient: A Personal Reflection

My name is Timothy Ray Brown and I am the first person in the world to be cured of HIV.

Published
08 January 2015
From
AIDS Research and Human Retroviruses
Elite controllers may pay a high price for their low viral load

About one in 200 people with HIV maintains an undetectable viral load and high CD4 counts without having to take antiretroviral therapy (ART). These so-called ‘elite controllers’

Published
07 January 2015
By
Gus Cairns
HIV vaccines should avoid viral target cells, primate model study suggests

Vaccines designed to protect against HIV can backfire and lead to increased rates of infection. This unfortunate effect has been seen in more than one vaccine clinical trial. Scientists at Yerkes National Primate Research Center, Emory University, have newly published results that support a straightforward explanation for the backfire effect: vaccination may increase the number of immune cells that serve as viral targets.

Published
04 January 2015
From
EurekAlert
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