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First evidence of HIV reservoirs in macrophages

Basic scientists in France have recently discovered that macrophages located in urethral tissue can contribute to cellular HIV reservoirs, and that the quantity of these specific immune

Published
12 February 2019
By
Alain Volny-Anne
HIV-1 protein suppresses immune response more broadly than thought

Scientists have revealed how a protein produced by HIV-1 plays a broader role in suppressing the immune system's response to infection than previously thought.

Published
06 February 2019
From
Eurekalert Inf Dis
HIV Hidden in Patients' Cells Can Now Be Accurately Measured

Researchers can now quickly and accurately count a hidden, inactive form of the human immunodeficiency virus (HIV) that lurks in patients' cells. This version of HIV embeds into cells' genomes and can persist despite otherwise successful therapies - thwarting attempts to cure the infection.

Published
31 January 2019
From
Howard Hughes Medical Institute
Two new types of cell therapy could target reservoir cells and permanently stop HIV infection

Two studies published last month described promising new approaches which could stop HIV infecting cells. They could either eliminate or permanently suppress the activity of the so-called

Published
31 January 2019
By
Gus Cairns
HIV protein function that slows migration of T cells also improves viral survival

A study from a Massachusetts General Hospital (MGH) research team has identified the specific function of a protein found in HIV and related viruses that appears to slow down viral spread in the earliest stages of infection. But they also found that, after initially slowing down the spread of infection, that function may help the virus survive later on by evading the immune response.

Published
15 January 2019
From
Medical Xpress
Larger HIV Reservoirs Found in Those with Clade B Subtype

A study team led by investigators from Simon Fraser University in Canada have made a key discovery on how viral factors, such as HIV subtypes, impact the size of the virus reservoirs in individuals with HIV.

Published
15 January 2019
From
Contagionlive.com
The Road Ahead for HIV Cure Research

Today, with better understanding of the complex task at hand, cure researchers are investigating multiple avenues and taking the long view.

Published
08 January 2019
From
Poz
HIV Establishes Reservoir Within Three Days in Monkeys

Beginning six months of treatment within two days following infection prevented viral rebound in at least some animals in a recent study.

Published
01 January 2019
From
Poz
AIDS - an approach for targeting HIV reservoirs

(Institut Pasteur) Current HIV treatments need to be taken for life by those infected as antiretroviral therapy is unable to eliminate viral reservoirs lurking in immune cells. Institut Pasteur scientists have identified the characteristics of CD4 T lymphocytes that are preferentially infected by the virus. Thanks to metabolic activity inhibitors, the researchers have managed to destroy these infected cells, or 'reservoirs', ex vivo. Their findings were published in the journal Cell Metabolism on Dec. 20, 2018.

Published
20 December 2018
From
Eurekalert Medicine & Health
The HIV/AIDS Activists Transformed Genetic Engineering

Over the past decade, a group of HIV activists has helped pioneer gene therapy.

Published
20 December 2018
From
The Atlantic
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Community Consensus Statement on Access to HIV Treatment and its Use for Prevention

Together, we can make it happen

We can end HIV soon if people have equal access to HIV drugs as treatment and as PrEP, and have free choice over whether to take them.

Launched today, the Community Consensus Statement is a basic set of principles aimed at making sure that happens.

The Community Consensus Statement is a joint initiative of AVAC, EATG, MSMGF, GNP+, HIV i-Base, the International HIV/AIDS Alliance, ITPC and NAM/aidsmap
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This content was checked for accuracy at the time it was written. It may have been superseded by more recent developments. NAM recommends checking whether this is the most current information when making decisions that may affect your health.

NAM’s information is intended to support, rather than replace, consultation with a healthcare professional. Talk to your doctor or another member of your healthcare team for advice tailored to your situation.