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Side-effects news

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New and experimental hepatitis C treatment
Incivek Rash Reports: What HIV/Hepatitis C-Coinfected People Need to Know

It turns out that Incivek (telaprevir), one of the HCV protease inhibitors approved last year, is also associated with rash. About half of patients who take Incivek get a rash. It can sometimes be itchy, too. Most of the time the rash is mild or moderate.

Published
18 May 2012
From
The Body
Cardiovascular disease
Doubt Cast on the ‘Good’ in ‘Good Cholesterol’

A study in the Lancet that makes use of powerful databases of genetic information has found that raising the levels of high-density lipoprotein HDL, the so-called 'good' cholesterol, may not reduce heart disease risk as was thought.

Published
17 May 2012
From
New York Times
New and experimental treatments
Gilead’s Quad Pill Raises Kidney Questions, FDA Says

Gilead Sciences Inc's experimental HIV pill Quad may need additional monitoring because of kidney damage seen in studies, U.S. regulators said.

Published
09 May 2012
From
Bloomberg Business Week
Changing treatment
Treatment switches becoming less common, side-effects still the key reason for switching

The number of people who need to change their antiretroviral drug regimen has declined significantly in recent years, Alison Boyle of the Chelsea & Westminster Hospital, London

Published
24 April 2012
By
Roger Pebody
Side-effects
Why it's time to say goodbye to stavudine...everywhere

Concerns about a proposed comparative trial of 40mg and 20mg (low-dose) stavudine in South Africa.

Published
16 April 2012
From
South African Journal of HIV Medicine
Drug interactions and pharmacokinetics
Genetic testing for drug intolerance

Intolerance to a drug is something most people learn about themselves only after it's prescribed. "There are some tumour drugs, for certain cancers, that 70% of the population won't respond to. For some asthma drugs, it's 40%," says Dingermann, who has been collecting research on the topic for the past four years.

Published
16 April 2012
From
The Guardian
Side-effects
CROI: Crofelemer Reduces Diarrhea in People with HIV; FDA Grants Priority Review

A plant compound known as crofelemer significantly decreased the frequency of secretory diarrhea in HIV positive patients, researchers reported at the 19th Conference on Retroviruses and Opportunistic Infections (CROI 2012) last month in Seattle. The U.S. Food and Drug Administration (FDA) has given crofelemer priority review status and is expected to take action by early June.

Published
13 April 2012
From
HIVandHepatitis.com
Side-effects
Can I Get A Witness! Authentic Voices Tell the Story of Neuropathy

Authors, scientists, doctors, journalists and bloggers can write about neuropathy until they're blue in the face but there's no substitute for hearing people tell their own stories. This post is therefore given over to some of the men and women with both HIV and Neuropathy who have opened their hearts on forums and in blogs across the Net. There are many, many more!

Published
12 April 2012
From
The Body
Bone problems
CROI: Switching to Tenofovir Increases Bone Turnover, Raltegravir Can Improve Bone Density

HIV positive people who substituted tenofovir (Viread) for zidovudine (AZT; Retrovir) in their antiretroviral regimen showed elevated levels of biomarkers associated with bone turnover and decreased bone mineral density (BMD), researchers reported at the 19th Conference on Retroviruses and Opportunistic Infections (CROI 2012) last month in Seattle.

Published
11 April 2012
From
HIVandHepatitis.com
Child developmental issues
Tenofovir use during pregnancy doesn't affect infant size or weight at birth, but may by one year of age

Use of tenofovir during pregnancy does not have an adverse impact on infant weight or size at birth, according to a large US study published in the

Published
03 April 2012
By
Michael Carter
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