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People taking a large number of non-HIV-related medications more likely to stop or change HIV drugs

HIV-positive patients who are taking a large number of medications for the treatment of non-HIV-related conditions are at increased risk of stopping or changing their antiretroviral therapy (ART),

Published
27 January 2016
By
Michael Carter
D:A:D study: long-term treatment with tenofovir associated with increased risk of serious liver disease

Long-term therapy with the antiretroviral drug tenofovir increases the risk of end-stage liver disease and liver cancer, according to data from the D:A:D study published

Published
21 January 2016
By
Michael Carter
Viread (Tenofovir, TDF) Linked With Liver Disease and Cancer

Long-term use of Viread (tenofovir disoproxil fumarate, or TDF) is associated with an increased risk of end-stage liver disease (ESLD) as well as hepatocellular carcinoma (HCC, the most common form of liver cancer) among people with HIV.

Published
14 January 2016
From
Poz
Short- or Medium-Term PrEP Is Safer Than Aspirin

Truvada as pre-exposure prophylaxis (PrEP) against HIV has comparable safety to aspirin, at least for the short- and medium-term.

Published
13 January 2016
From
AIDSMeds
South African Medicines Agency approves PrEP

The South African Medicines Control Council (MCC) has approved PrEP. So far it has issued a brief statement, saying that on 28 November it "Approved the use of the fixed-dose combination of tenofovir disoproxyl fumarate and emtricitabine to include pre-exposure prophylaxis of HIV(also referred to as PrEP)." The MCC names the separate drugs rather than Truvada, as South Africans take generic versions of the drugs made on licence locally. The MCC does not recommend criteria for PrEP access or name specific populations but instead soliticts applications from organisations that wish to provide PrEP. Its one stipulation is that, since using the drugs for prevention is a new field, records of adverse events in people offered PrEP should be kept by providers.

Published
08 December 2015
From
South African MCC
Ipergay PrEP study results published

The results from the Ipergay study of intermittent pre-exposure prophylaxis (PrEP) were published in the New England Journal of Medicine (NEJM) on 1 December, World AIDS

Published
02 December 2015
By
Gus Cairns
Priorities for HIV care: the perspectives of healthcare providers and patients

Virological suppression and co-morbidities are the main focus of consultations between HIV healthcare providers (HCPs) and their patients, according to results of a study conducted by NAM and

Published
02 November 2015
By
Michael Carter
Body fat changes and lactic acidosis with HIV medicines: EMA recommends removal of class warnings for several medicines

The European Medicines Agency (EMA) has updated the advice on the risk of body fat changes and lactic acidosis with medicines for the treatment of human immunodeficiency virus (HIV) infection. As a result, HIV medicines will no longer require a warning concerning fat redistribution in their product information, and a number of medicines of the class ‘nucleoside and nucleotide analogues’ will no longer require a warning about lactic acidosis.

Published
26 October 2015
From
European Medicines Agency
Benefits of early HIV treatment are clear, but issues raised by START and D:A:D remain unresolved

The long-running controversy over when to start antiretroviral therapy (ART) has been definitively answered, but research is still needed to fully understand the implications of the large START

Published
23 October 2015
By
Liz Highleyman
Studies continue to support tenofovir alafenamide combination pill as it nears US approval

A single-tablet regimen containing a new formulation of tenofovir maintained viral suppression for people switching from other combinations and was associated with improved kidney function and bone health,

Published
19 October 2015
By
Liz Highleyman
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