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Integrase inhibitors do not raise risk of IRIS in severely immunocompromised people

Use of an integrase inhibitor, which can bring down viral load rapidly, was not associated with an increased risk of immune reconstitution inflammatory syndrome (IRIS) in people

Published
27 March 2018
By
Liz Highleyman
Raltegravir-Intensified ART: More Rapid Declines in HIV Viral Load But No Impact On IRIS

At the 25th Conference on Retroviruses and Opportunistic Infections (CROI) Diana Gibb, MD, professor of epidemiology, program leader of the Pediatric Program of trials and cohorts at the Medical Research Council Clinical Trials Unit at UCL, London, shared results from a REALITY trial (ISRCTN43622374) which explored the impact of raltegravir intensification of first-line antiretroviral therapy (ART) on immune reconstitution inflammatory syndrome (IRIS).

Published
13 March 2018
From
Contagion Live
Deadly cryptococcal fungi found in public spaces in South Africa

After tuberculosis, cryptococcal meningitis is the leading cause of death in HIV/AIDS patients in Sub-Saharan Africa.

Published
08 December 2017
From
Science Daily
HIV: MSF concerned by high numbers of AIDS deaths in sub-Saharan Africa

Global attention is needed to prevent and treat AIDS in antiretroviral era, with 50 per cent of hospital admissions in MSF hospitals already on treatment and showing signs of clinical failure.

Published
25 July 2017
From
Médecins Sans Frontières (MSF) International
Improved treatment for cryptococcal meningitis in HIV could save thousands of lives – if generic drug becomes available

Urgent action is needed to improve access to the antifungal drug flucytosine, say investigators, following the presentation of the results of a trial showing that treatment containing

Published
24 July 2017
By
Keith Alcorn
WHO recommends package of tests, treatment and prevention for 'urgent need' people with HIV with low CD4 counts

A new package of measures to ensure rapid initiation of antiretroviral treatment and diagnosis of opportunistic infections has been recommended by the World Health Organization (WHO) to

Published
23 July 2017
By
Keith Alcorn
People with HIV have impaired respiratory health, even when viral load is undetectable

HIV-positive people have impaired respiratory health, even when they have viral suppression with antiretroviral therapy (ART), investigators from London report in HIV Medicine. Respiratory health was compared between HIV-positive

Published
23 May 2017
By
Michael Carter
Integrase inhibitors may increase risk of IRIS in late presenters for HIV treatment

HIV integrase inhibitors such as dolutegravir and raltegravir may increase the risk of immune reconstitution inflammatory syndrome (IRIS), studies from the Netherlands and France presented

Published
01 March 2017
By
Keith Alcorn
Pneumococcal infections decrease in patients with suppressed HIV

Pneumococcal infections among patients with virologically suppressed HIV decreased significantly in recent years, according to data from a retrospective, case-controlled study.

Published
08 November 2016
From
Healio
Package of prophylaxis against infections reduces the risk of death for people starting HIV treatment very late

A package of enhanced prophylaxis against infections significantly reduced the risk of death in adults and children with advanced HIV disease after starting antiretroviral treatment in a

Published
08 August 2016
By
Keith Alcorn
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Community Consensus Statement on Access to HIV Treatment and its Use for Prevention

Together, we can make it happen

We can end HIV soon if people have equal access to HIV drugs as treatment and as PrEP, and have free choice over whether to take them.

Launched today, the Community Consensus Statement is a basic set of principles aimed at making sure that happens.

The Community Consensus Statement is a joint initiative of AVAC, EATG, MSMGF, GNP+, HIV i-Base, the International HIV/AIDS Alliance, ITPC and NAM/aidsmap
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This content was checked for accuracy at the time it was written. It may have been superseded by more recent developments. NAM recommends checking whether this is the most current information when making decisions that may affect your health.

NAM’s information is intended to support, rather than replace, consultation with a healthcare professional. Talk to your doctor or another member of your healthcare team for advice tailored to your situation.