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Lipodystrophy news

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Drug that reduces abdominal fat in HIV patients also may reduce fat in liver

The only drug to receive Food and Drug Administration approval for reduction of the abdominal fat deposits that develop in some patients receiving antiviral therapy for HIV infection may also reduce the incidence of fatty liver disease in such patients. Massachusetts General Hospital investigators report that six months of daily injections of tesamorelin significantly reduced fat in the liver without affecting glucose metabolism.

Published
19 July 2014
From
Eurekalert Medicine & Health
Unusual and rare complication described in San Francisco

Doctors in San Francisco have reported an unusual and rare finding—an apparently harmless but disfiguring condition called cutis verticis gyrata (CVG) on the heads of four HIV-positive men. In CVG, the skin on the head becomes raised in parts and depressed in others, forming ridges and furrows.

Published
09 December 2013
From
CATIE
Liquid Injectable Silicone Effective, Safe for Treating HIV Patients with Facial Lipoatrophy

Research in British Columbia, Canada, indicates that liquid injectable silicone administered properly has potential as a safe, effective, natural feeling treatment for patients with HIV-associated facial lipoatrophy (FLA). The researchers tested liquid injectable silicone because temporary filler treatments were not permanent and could result in high costs.

Published
04 June 2013
From
Healio
Protein Structure Discovery Could Lead to Better Treatments for HIV, Early Aging

Researchers at the University of Virginia School of Medicine have determined the molecular structure of a protein whose mutations have been linked to several early aging diseases, and to side effects of common HIV and AIDS medications.

Published
11 April 2013
From
University of Virginia press release
Almost three-quarters of people starting HIV therapy in Tanzania have dyslipidemia after three years of treatment

Approximately 75% of HIV-positive patients in Tanzania had lipid abnormalities three years after starting antiretroviral therapy, research published in the online edition of Clinical Infectious Diseases shows.

Published
28 March 2013
By
Michael Carter
Health Canada rejects tesamorelin for lipodystrophy

After consideration of the NDS, Health Canada decided that the risks of tesamorelin outweighed its benefits under the proposed conditions of use.

Published
13 March 2013
From
Theratechnologies press release
Mark S. King: I'm Gonna Wipe That AIDS Right Off My Face

It was all well and good to be front and center as an HIV-positive man during the first years of the AIDS crisis. It's easier being a role model when your face looks good on the poster. But then, slowly but surely, a common side effect of HIV medications, facial wasting, began to appear.

Published
30 January 2013
From
Huffington Post
The Bio-Alcamid disaster

“Nightmare.” That’s how one man described a weeks-long ordeal involving ad hoc surgery, repeated infections and some hefty out-of-pocket fees – all caused by a device that was once thought to be a miracle for those dealing with the visible signs of HIV.

Published
08 October 2012
From
Xtra
The mirror has two faces - a personal account of using facial filler for lipoatrophy

In the end, for me the few small lumps, the cost of treatment, and the pain were all a small price to pay for what it has ultimately done for my self-esteem. I feel better about myself overall, because I look healthier.

Published
28 September 2012
From
Positively Aware
High rate of infections in people with HIV receiving Bio-Alcamid treatment for facial lipoatrophy

Bio-Alcamid treatment for HIV-related lipoatrophy is associated with a high-rate of infectious complications, Canadian investigators report in the online edition of Clinical Infectious Diseases. The infections typically developed

Published
10 September 2012
By
Michael Carter
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