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New study reveals how HIV enters cell nucleus

Scientists have solved a mystery that has long baffled HIV researchers: How does HIV manage to enter the nucleus of immune system cells? The discovery could lead to effective new drugs to treat HIV/AIDS.

Published
23 June 2016
From
Science Daily
WHO confirms antiretroviral therapy reduces the risk of life-threatening HIV-related infections

Adults and children with HIV who start antiretroviral therapy (ART) as early as possible reduce their risk of developing serious HIV-related infections, according to new findings published in the journal Clinical Infectious Diseases on 15 June 2016.

Published
22 June 2016
From
World Health Organization
Men With HIV Age Faster According to DNA Methylation Study

Infection with HIV may be associated with accelerated cellular aging, according to a new study in which researchers analyzed DNA methylation patterns of men with HIV infection. The study provides a possible explanation for why people with HIV who take antiretroviral medications often develop age-related conditions such as cardiovascular disease, hypertension, bone fractures, and renal failure years earlier than those who are uninfected.

Published
16 June 2016
From
JAMA
Scientists map the global spread of HIV – through the Western world and beyond – for the first time

Scientists have mapped the spread of the HIV virus around the globe after it reached the United States in the early 1970s. Their study finds that HIV travelled from the US to Western Europe on a number of occasions, whereas Central and Eastern Europe remained isolated for the most part of the early epidemic. The study describes the global spread of HIV-1 subtype B, but not of other subtypes.

Published
15 June 2016
From
University of Oxford press release
Can We Say Goodbye to the Word AIDS?

What do we lose by freeing ourselves from the word AIDS—or, what might we have to gain? It’s a question provoked by advances in HIV treatment and care and changes in the way that people live with and experience HIV and AIDS.

Published
06 May 2016
From
BETA blog
HIV Spreads Through the Body Much Faster Than Previously Thought

HIV spreads much more rapidly through the body after initial infection than previously believed, apparently causing immediate immune reactions that enable its replication. Publishing their findings in the journal Cell, researchers vaginally exposed 44 rhesus monkeys to SIV, HIV’s simian cousin, and analyzed the animals during the first few days post-infection.

Published
25 April 2016
From
POZ
HIV infection prematurely ages humans by an average of 5 years

Thanks to combination antiretroviral therapy, many people with HIV can be expected to live decades after being infected. Yet doctors have observed that these patients often show signs of premature aging. Now a study published April 21 in Molecular Cell has applied a highly accurate biomarker to measure just how much HIV infection ages people at the biological level -- an average of almost 5 years.

Published
22 April 2016
From
Eurekalert Inf Dis
New research explains why HIV is not cleared by the immune system

Scientists have identified a human (host) protein that weakens the immune response to HIV and other viruses. The findings have important implications for improving HIV antiviral therapies, creating effective viral vaccines, and advance a new approach to treat cancer.

Published
15 April 2016
From
Science Daily
What Is Chronic Inflammation and Why Is It Such a Big Deal for People With HIV?

A primer on the harms of HIV-related chronic inflammation, what treatments are being researched and what you can do to reduce inflammation and improve your long-term health.

Published
06 April 2016
From
Poz
How HIV infection increases the risk of tuberculosis

A study published in PLOS Pathogens suggests that it is not a general weakening of the immune system by HIV that initially leads to loss of Mtb control, but rather that HIV is associated with a failure to prevent harmful immune responses. As HIV disease progresses, the weakening immune system's focus on antiviral responses leaves it largely defenseless against the Mtb pathogen.

Published
18 March 2016
From
HIV / AIDS News From Medical News Today
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