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High-risk drug practices tighten grip on London gay scene

The rise in use of crystal methamphetamine, with more men injecting drugs, is creating a perfect storm for transmission of both HIV and HCV, as well as a catalogue of mental health problems.

Published
11 January 2013
From
The Lancet
Roche Scientists Uncover Unexpected Enzyme Activity in HCV RNA Polymerase

Today, Roche scientists detail the discovery of a new enzyme activity that allows HCV polymerase to remove nucleosides and nucleoside analogues from RNA molecules. This could lead to HCV polymerase counteracting the activity of nucleoside analogs and result in the development of pathways enabling HCV resistance.

Published
11 January 2013
From
Biospace
Nucleotide Polymerase Inhibitors - The Search For A Safe Interferon Free Trial

While the HCV community is waiting in the wings for the first all interferon-sparing therapy to make its way down the pipeline and hopefully all the way to FDA approval, the search for a clinical trial without interferon has become a reality.

Published
10 January 2013
From
HCV New Drugs Research
Idenix May Drop Delayed Hepatitis C Drug for New Versions

Idenix Pharmaceuticals Inc. (IDIX), a developer of hepatitis C drugs, may shelve experimental treatments currently on hold by U.S. regulators and focus on different versions, Chief Executive Officer Ron Renaud said.

Published
10 January 2013
From
Businessweek
Hepatitis B treatment and care in the UK need to evolve to keep pace with the global epidemic

“Persistent HBV [hepatitis B virus] infection has changed its face in the UK,” research published in the online edition of Clinical Infectious Diseases shows. The study found considerable

Published
09 January 2013
By
Michael Carter
Gilead Provides Update on Hepatitis C Development Programs

Sustained Virologic Response Achieved with Oral Regimen of Sofosbuvir, GS-5885 and Ribavirin in 9/9 Null Responder Genotype 1 Hepatitis C Patients; Second Phase 3 Study Evaluating Fixed-dose Combination of Sofosbuvir and GS-5885 to Begin Later this Month.

Published
08 January 2013
From
Gilead press release
Achillion Reports Interim Results on ACH-3102

Enrollment completed in pilot Phase 2a study of ACH-3102 and ribavirin for genotype 1b CC patients; up to 12 weeks of once daily ACH-3102 appears safe and well tolerated with no on-treatment virologic breakthrough observed to date.

Published
08 January 2013
From
Achillion press release
Small UK study suggests that depression does not have an impact on hepatitis C treatment outcomes in people co-infected with HIV

Depression does not influence hepatitis C treatment outcomes in people co-infected with HIV, according to the results of a small study conducted in Brighton and presented to

Published
04 January 2013
By
Michael Carter
Year in Review: Dueling HCV Screening Recommendations

As part of the Year in Review series, MedPage Today reporters are revisiting major news stories and following up with an analysis of the impact of the original report, as well as subsequent news on the topic. In terms of hepatitis C screening recommendations, there's been controversy and concern.

Published
03 January 2013
From
MedPage Today
Top 12 HIV and Hepatitis Stories of 2012

HIVandHepatitis.com reviews some the year's major HIV and viral hepatitis news highlights. On the HIV front, U.S. treatment guidelines recommended antiretroviral therapy (ART) for all HIV positive people, Truvada was approved for pre-exposure prophylaxis (PrEP), and HIV criminalization and cure research were highlighted at the International AIDS Conference in July. Promising findings were reported for several interferon-free oral regimens for hepatitis C, experimental tuberculosis (TB) drugs showed good results, and the Affordable Care Act remained on track.

Published
03 January 2013
From
HIVandHepatitis.com

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