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Bristol-Myers oral hepatitis C regimen looks competitive -study

The combination therapy, which involves three direct acting antiviral drugs that each attack different targets needed for replication of the hepatitis virus, achieved cure rates as high as 94 percent when given for either 12 weeks or 24 weeks, according to results of the small study.

Published
24 April 2013
From
Reuters
The Hepatitis C Drug Pipeline Report: A Groundswell to Become a Sea Change

Frantic competition between the major pharmaceutical players has accelerated progress on new hepatitis C virus (HCV) therapies to a breakneck speed.

Published
19 April 2013
From
Hep: Your Guide to Hepatitis
Elevated prevalence of HIV and viral hepatitis in men injecting anabolic steroids

Addressing a topic that has received remarkably little research attention over the years, Dr Vivian Hope of Public Health England told the British HIV Association conference yesterday

Published
18 April 2013
By
Roger Pebody
Liver disease a major cause of illness and death across the EU: action needed to save lives

Liver disease is the cause of a considerable burden of illness across the European Union (EU), investigators report in The Journal of Hepatology. The authors calculate that 170,000

Published
16 April 2013
By
Michael Carter
Roche to commercialize Hepatitis C drug in China with Ascletis

Swiss drugmaker Roche Holding AG said it had teamed up with biotech firm Ascletis to develop and commercialize its investigative drug danoprevir in China for the treatment of the Hepatitis-C virus.

Published
15 April 2013
From
Yahoo! News
Depression in HCV Often Resolves After Interferon Treatment

Depression affects up to 50% of patients with chronic hepatitis C virus (HCV) infection receiving treatment with interferon, but it appears to be self-limiting and does not usually require antidepressant therapy, new research suggests.

Published
12 April 2013
From
Medscape (requires registration)
Hepatitis C epidemic in US gay men is decades old

Hepatitis C virus (HCV) transmissions have been occurring in gay men since at least the early years of the HIV epidemic, investigators from the US report in

Published
10 April 2013
By
Michael Carter
Gilead Submits New Drug Application to U.S. FDA for Sofosbuvir for the Treatment of Hepatitis C

Sofosbuvir Would Form Basis of First All-Oral Regimen for HCV Genotype 2 and 3 Patients, and Interferon-Sparing Regimen for Genotype 1 Patients.

Published
09 April 2013
From
Gilead press release
Vertex Enters Agreement with Bristol-Myers Squibb for Phase 2 All-Oral Studies of VX-135 in Combination with Daclatasvir for the Treatment of Hepatitis C

Two Phase 2 studies to evaluate once-daily combination of Vertex's investigational nucleotide analogue VX-135 and BMS' investigational NS5A replication complex inhibitor daclatasvir.

Published
08 April 2013
From
Vertex press release
Hepatitis C Viral Load Fluctuates Without Treatment

Fluctuations in circulating hepatitis C virus RNA could be "clinically meaningful" in a substantial number of patients with chronic infection, and could influence the best time to prescribe antiviral therapy.

Published
05 April 2013
From
Medscape (requires registration)

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