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Hepatitis C treatment side-effects news

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Merck combination suppresses HCV in mono-infected and co-infected patients

An all-oral combination of the hepatitis C virus (HCV) protease inhibitor MK-5172 and NS5A inhibitor MK-8742, with or without ribavirin, demonstrated promising end-of-treatment viral suppression in people

Published
21 March 2014
By
Liz Highleyman
Faldaprevir plus interferon and ribavirin cures hepatitis C in most people with HIV/HCV co-infection

The hepatitis C protease inhibitor faldaprevir added to pegylated interferon and ribavirin cured hepatitis C in nearly three-quarters of people with genotype 1 hepatitis C virus

Published
05 March 2014
By
Liz Highleyman
Six-week oral treatment can cure hard-to-treat hepatitis C patients

Interferon- and ribavirin-free treatment using sofosbuvir, ledipasvir and a third direct-acting drug for as little as six weeks can cure most previously untreated people with genotype 1

Published
04 March 2014
By
Liz Highleyman
Low lymphocyte count a risk factor for infections for people taking HCV therapy

A low lymphocyte count is associated with an increased risk of infections during hepatitis C virus (HCV) treatment that includes pegylated interferon and ribavirin, according to the

Published
16 January 2014
By
Michael Carter
Faldaprevir demonstrates good early response in genotype 1 HIV/HCV co-infection

The HCV protease inhibitor faldaprevir added to pegylated interferon and ribavirin increased the likelihood that HIV/HCV co-infected people would achieve a sustained virological response at four weeks

Published
22 October 2013
By
Liz Highleyman
Simeprevir with interferon effective for HIV/HCV co-infected people with genotype 1 hepatitis C

Adding the direct-acting hepatitis C drug simeprevir to pegylated interferon and ribavirin produced high response rates for HIV-positive people co-infected with HCV genotype 1, researchers reported

Published
21 October 2013
By
Liz Highleyman
Interferon-free therapy alters lipid metabolism, glucose homeostasis in chronic HCV patients

Patients with chronic hepatitis C treated with an interferon-free regimen consisting of sofosbuvir and ribavirin experienced changes in LDL, triglycerides, hemoglobin A1C and metabolic and hepatic lipid gene expression in a study presented at ID Week 2013.

Published
14 October 2013
From
Healio Hepatology
Daclatasvir works well against hepatitis C either with interferon or in all-oral regimen

A short 12- or 16-week triple regimen of daclatasvir plus pegylated interferon/ribavirin cured more people than a 24-week course of pegylated interferon/ribavirin alone, whilst an interferon-free regimen containing

Published
10 October 2013
By
Liz Highleyman
Treating HCV genotypes 2 and 3 in HIV/HCV co-infected people

People co-infected with HIV and HCV, mostly with hepatitis C virus (HCV) genotype 3, responded about as well as HIV-negative people to interferon-based therapy after taking

Published
27 September 2013
By
Liz Highleyman
HIV/HCV co-infected people can do well on hepatitis C triple therapy despite contraindications

Nearly three-quarters of HIV/HCV co-infected patients in the French HEPAVIH cohort achieved end-of-treatment virological response to hepatitis C treatment with telaprevir plus pegylated interferon/ribavirin, even though one-third had

Published
22 July 2013
By
Liz Highleyman
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