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Liver toxicity uncommon with modern antiretroviral drugs, but higher risk for HIV/HCV coinfected

Recently approved antiretroviral drugs are generally well-tolerated and seldom cause serious liver enzyme elevations, although protease inhibitors are somewhat more likely to do so, researchers reported in the November 28, 2012, advance online edition of AIDS. People with HIV/HCV coinfection are more likely to experience liver toxicity, however.

Published
06 December 2012
From
HIVandHepatitis.com
Copy of Liver toxicity uncommon with modern antiretroviral drugs, but higher risk for HIV/HCV coinfected

Recently approved antiretroviral drugs are generally well-tolerated and seldom cause serious liver enzyme elevations, although protease inhibitors are somewhat more likely to do so, researchers reported in the November 28, 2012, advance online edition of AIDS. People with HIV/HCV coinfection are more likely to experience liver toxicity, however.

Published
06 December 2012
From
HIVandHepatitis.com
Diet quality predicts HIV progression and death in resource-poor settings

The more diverse and nutrient-rich the diet before starting antiretroviral treatment (ART), the less severe HIV disease progression is, and the less likely death occurs, researchers report in

Published
06 December 2012
By
Carole Leach-Lemens
PI monotherapy for HIV — an idea whose time has passed?

Patients who switched from suppressive triple-drug therapy to boosted protease-inhibitor monotherapy had unreasonably high rates of treatment failure.

Published
05 December 2012
From
Journal Watch
Crucial step in AIDS virus maturation simulated for first time

Bioinformaticians in Spain have used molecular simulation techniques to explain a specific step in the maturation of the HIV virions, i.e., how newly formed inert virus particles become infectious, which is essential in understanding how the virus replicates. These results could be crucial to the design of future antiretrovirals.

Published
05 December 2012
From
Science Daily
Swiss research identifies factors associated with use of non-recommended HIV therapy

New Swiss research shows the importance of observing antiretroviral treatment guidelines, even in people who have well-controlled HIV infection. Published in the online edition of the Journal

Published
05 December 2012
By
Michael Carter
'Real-world' evidence shows that antiretroviral therapy reduces risk of HIV transmission in heterosexual couples

A study conducted in China has provided 'real-world' evidence of the impact of antiretroviral therapy on the risk of transmission in heterosexual couples. Published in The Lancet,

Published
04 December 2012
By
Michael Carter
THERAVECTYS is granted authorization from the French and Belgian regulatory agencies to launch a Phase III clinical trial for its anti-HIV therapeutic vaccine candidate

The world’s first use of lentiviral vector technology in the vaccine field .

Published
04 December 2012
From
EATG
Redefining Expanded Access Programs for patients with MDR-HIV

It is time to create a new paradigm to break the vicious cycle of single drug access that has failed these patients.

Published
04 December 2012
From
GMHC Treatment Issues
Out-of-clinic adherence club for delivery of ARVs shows better retention than standard of care

An out-of-clinic model of HIV treatment delivery in South Africa has shown superior results to the standard in-clinic delivery of antiretrovirals (ARVs), according to results of

Published
03 December 2012
By
Lesley Odendal

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