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Merck Receives FDA Approval for ISENTRESS(R) (raltegravir) for Pediatric Oral Suspension

The oral suspension may be used in patients as young as four weeks of age, weighing at least 3 kg to less than 20 kg. The safety and efficacy of ISENTRESS have not been established in infants less than four weeks of age. Formulations of ISENTRESS for specific populations now include oral suspension, chewable tablets and film-coated tablets.

Published
09 January 2014
From
Wall Street Journal
Vertex's VX-765 holds promise for HIV treatment

In a recent report in the journal Science researchers at University of California, San Francisco and the Gladstone Institute of Virology and Immunology found that most CD4 T-cells aren't killed by the HIV virus directly, but by the body's cellular "suicide response" via a protein called caspase-1 (or interleukin-1 converting enzyme) and stopping this process prevents the progression of HIV to AIDS. What's more, the researchers showed that this suicide process is specifically inhibited by Vertex Pharmaceutical's caspase-1 inhibitor VX-765.

Published
07 January 2014
From
Motley Fool
African studies identify strategies for improving treatment adherence, retention in care

Getting people tested for HIV is one thing; getting them onto antiretrovirals (ARVs) another; and retaining them in care for a long period something else entirely. A

Published
07 January 2014
By
Mara Kardas-Nelson
Life expectancy now considerably exceeds the average in some people with HIV in the US

A study from the US has found that some groups of people with HIV, especially those treated before their CD4 count falls below 350 cells/mm3, now have life

Published
06 January 2014
By
Gus Cairns
HIV/AIDS Editors' Choice: Top Stories of 2013

The biggest change in HIV treatment over the past year has been the continued emergence of integrase inhibitor–based regimens as top options for first-line therapy.

Published
06 January 2014
From
NEJM Journal Watch
Relapse of 'cured' HIV patients spurs AIDS science on

Scientists seeking a cure for AIDS say they have been inspired, not crushed, by a major setback in which two HIV positive patients believed to have been cured found the virus re-invading their bodies once more.

Published
06 January 2014
From
Reuters
30 years on, Gallo sees 'functional cure' for HIV

It has been 30 years since Dr. Robert Gallo became internationally famous for his role in the discovery of the virus that causes acquired immune deficiency syndrome. He has wrestled with the question of a cure countless times since then. But only within the last year, he says, did he conclude that working toward a "functional cure" makes the most sense.

Published
06 January 2014
From
Baltimore Sun
Lack of drug data 'extreme concern'

The lack of data on the effectiveness of medicines available to doctors and researchers is "of extreme concern" say a group of MPs. The Public Accounts Committee is calling for all data on drugs being prescribed in the UK to be made available.

Published
03 January 2014
From
BBC Health
HIV cure may lie in radioimmunotherapy

A new study suggests targeting HIV with radioimmunotherapy could eradicate HIV from infected cells. If given in conjunction with highly active antiretroviral therapy, it may form the basis of a cure.

Published
03 January 2014
From
Medical News Today
A Year-End Look At HIV Treatments in 2013

Looking ahead into 2014, convenient combination treatments like Gilead's Stribild could substantially improve the daily lives of patients. In addition, newer integrase inhibitors like Isentress and Tivicay could chip away at the dominance of Viread-based drugs. HIV vaccines, now nearly three decades overdue, could eventually arrive as well. RV 144 and Inovio's HIV vaccines are two promising projects which could eventually save millions of lives and render HIV cocktail drugs from Gilead and ViiV Healthcare obsolete.

Published
29 December 2013
From
Motley Fool

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