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Clinical trials news

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Three countries get first malaria vaccine

The world's first vaccine against malaria will be introduced in three countries - Ghana, Kenya and Malawi - starting in 2018. The four-shot vaccine should prevent four in 10 cases of the disease.

Published
24 April 2017
From
BBC
The New War on Drugs: Trump policy on the FDA

A war against regulations intended to hold manufacturers accountable, protect drug safety and the health of the American public, and advance evidence-based and cost-effective care is questionable at best—and dangerous at worst.

Published
01 April 2017
From
TAG
Mariëtte Botes: ARV pioneer who became the victim of abuse and hostility

Dr Mariëtte Botes, who has died in Pretoria at the age of 50, was an early pioneer of antiretroviral cocktails that saved the lives of hundreds of thousands of people with Aids. But, reports The Times, while running a clinical trial at Kalafong Hospital in Pretoria in 1999, she became the target of a hostile campaign by Patricia de Lille, who was then an MP for the PAC, who accused her of abusing and exploiting her patients.

Published
16 March 2017
From
Medical Brief
What we know about the new England PrEP trial

@teamPrEPster, and other HIV advocate groups, will be keeping a watchful eye on development of the trial, not least to ensure that there are no further delays to its implementation.

Published
27 February 2017
From
Prepster
How to Keep HIV Cure-Related Trials Ethical: The Benefit/Risk Ratio Challenge

While high or unknown risks are a mainstay of early-phase trials in areas like cancer research, cure study participants typically have a safe and efficacious alternative to those risks: remaining on antiretrovirals. Can we justify asking patients who are doing well on antiretrovirals to accept the risk and uncertainty of many HIV cure-related trials? If we cannot, we might need to give up on the hope of curing HIV, or of achieving controlled remission.

Published
22 February 2017
From
BMJ Blogs
New NNRTI doravirine shows good efficacy in phase 3 study

Doravirine, an investigational next-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) from Merck, reduced HIV viral load as well as boosted darunavir in a phase 3 clinical trial of

Published
19 February 2017
By
Liz Highleyman
Vaccine trial: Community trust is key

Dr. Linda-Gail Bekker knows from more than 20 years in the field that researchers have to work hand in hand with the communities most affected if they want to halt an epidemic. And the townships are ground zero for HIV/AIDS in Cape Town.

Published
17 February 2017
From
Fred Hutch
Pharma industry shuns Trump push for radical shift at FDA

President Donald Trump's vow to roll back government regulations at least 75 percent is causing anxiety for some pharmaceutical executives that a less robust Food and Drug Administration would make it harder to secure insurance coverage for pricey new medicines.

Published
15 February 2017
From
Reuters
In the search for an HIV cure, David Evans explains “freedom” and how to better involve women & people of color

David Evans, director of research advocacy at Project Inform, talks about an ambitious HIV cure social science research project that will investigate some of the ethical and moral dilemmas cropping up in HIV cure research.

Published
09 February 2017
From
BETA blog
Trump wants to blow up the FDA. The drug industry? Not so much.

President Donald Trump wants to remake the Food and Drug Administration. But does anyone really want a deregulated FDA? STAT canvassed biopharma insiders, physicians, Wall Street analysts, and FDA veterans. Their verdict: Trump’s plan sounds like a solution in search of a problem.

Published
01 February 2017
From
STAT
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Community Consensus Statement on Access to HIV Treatment and its Use for Prevention

Together, we can make it happen

We can end HIV soon if people have equal access to HIV drugs as treatment and as PrEP, and have free choice over whether to take them.

Launched today, the Community Consensus Statement is a basic set of principles aimed at making sure that happens.

The Community Consensus Statement is a joint initiative of AVAC, EATG, MSMGF, GNP+, HIV i-Base, the International HIV/AIDS Alliance, ITPC and NAM/aidsmap
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This content was checked for accuracy at the time it was written. It may have been superseded by more recent developments. NAM recommends checking whether this is the most current information when making decisions that may affect your health.

NAM’s information is intended to support, rather than replace, consultation with a healthcare professional. Talk to your doctor or another member of your healthcare team for advice tailored to your situation.