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Women under-represented in HIV clinical trials

Less than a quarter of people taking part in clinical trials for antiretroviral medications are women, potentially limiting the generalisability of findings, according to a systematic review

Published
08 February 2016
By
Roger Pebody
New PrEP studies will be a challenge, statisticians warn

Two statisticians involved in the PROUD and iPrEx trials of pre-exposure prophylaxis (PrEP) warn that future trials to test new PrEP drugs and formulations may be extremely difficult

Published
26 January 2016
By
Gus Cairns
Collaboration and Conflict: Looking Back at the 30-Year History of the AIDS Clinical Trials Group

The AIDS Clinical Trials Group (ACTG) supported groundbreaking research that transformed a death-sentence disease into a chronic illness that could be managed for decades with medication. It is now the largest network of therapeutic clinical trial units in the world.

Published
23 December 2015
From
JAMA
NIH drops special 10% set-aside for AIDS research

In a major shakeup for the HIV/AIDS research community, the National Institutes of Health (NIH) today announced it will no longer support setting aside a fixed 10% of its budget—or $3 billion this year—to fund research on the disease. The agency also plans to reprogram $65 million of its AIDS research grant funding this year to focus more sharply on ending the epidemic.

Published
15 December 2015
From
Science
New PrEP trial aims to 'virtually eliminate' new HIV infections in New South Wales by 2020

NSW will become the first state in Australia to implement such a rapid and large-scale trial of HIV pre-exposure prophylaxis.

Published
01 December 2015
From
UNSW press release
Women are missing from HIV drug trials

In an analysis spanning several decades that included work done as recently as 2012, researchers found that women typically comprised about 11 percent of participants in trials investigating cures for HIV. Similarly, drug studies were only about 19 percent female and just 38 percent of vaccine trial subjects were women.

Published
05 October 2015
From
Reuters
Future of HIV cure research points to combination approach

The next five years of HIV research should shift gears from the classic single-therapy development model to moving directly from in vitro studies to combination therapy trials, authors argue in a new paper published online today.

Published
01 October 2015
From
US Military HIV Research Program press release
HIV patients should be included in early clinical trials of anti-TB drugs

Tuberculosis is the number one cause of death in HIV-infected patients in Africa and a leading cause of death in this population worldwide, yet the majority of these patients are excluded from the early stages in the development of new, anti-tuberculosis drugs, according to research.

Published
01 October 2015
From
Science Daily
U.S. Survey on Willingness to Participate in HIV Cure-Related Research: Your Opinion Matters (US readers only)

There has been an increase in HIV cure research in the recent years. We would like to find out how people living with HIV (or potential HIV cure research volunteers) perceive HIV cure research, including their willingness to participate in HIV cure studies. We would also like to find out what would help implement HIV cure studies. Your answers to these questions will be kept strictly confidential.

Published
16 September 2015
From
University of North Carolina
Pre-exposure prophylaxis to prevent the acquisition of HIV-1 infection (PROUD): effectiveness results from the pilot phase of a pragmatic open-label randomised trial

The Lancet publishes the results of the PROUD PrEP study which were announced at the CROI conference on 24 February this year - full text PDF available open-access. See http://www.aidsmap.com/page/2947319/ .

Published
10 September 2015
From
The Lancet
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