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Sophisticated HIV diagnostics adapted for remote areas

Diagnosing HIV and other infectious diseases presents unique challenges in remote locations that lack electric power, refrigeration, and appropriately trained health care staff. To address these issues, researchers have developed a low-cost, electricity-free device capable of detecting the DNA of infectious pathogens, including HIV-1.

Published
10 December 2014
From
Science Daily
Protease inhibitor monotherapy: darunavir/ritonavir less effective than three-drug therapy

Darunavir/ritonavir monotherapy results in a lower rate of viral suppression after 48 weeks when compared to darunavir/ritonavir plus two nucleoside reverse transcriptase inhibitors (NRTIs), but may

Published
07 November 2014
By
Keith Alcorn
Do emtricitabine and lamivudine have similar virological efficacy when used in first-line HIV therapy?

First-line antiretroviral regimens containing emtricitabine have superior virological efficacy to combinations containing lamivudine when combined with tenofovir and either nevirapine or efavirenz, Dutch investigators report in the online

Published
03 November 2014
By
Michael Carter
Effective treatments available for HIV patients not eligible for efavirenz regimens

HIV drug regimens that do not include efavirenz are effective as first-line antiretroviral therapy, a new American clinical trial found. The finding is important for patients who are not eligible for treatment with efavirenz, including women considering becoming pregnant and patients with a history of severe psychiatric disorders.

Published
07 October 2014
From
Science Daily
Switch From Efavirenz to Rilpivirine Quells CNS Toxicity, Improves Sleep

Switching from Atripla (efavirenz plus tenofovir/emtricitabine [TDF/FTC]) to Complera (Eviplera, rilpivirine plus TDF/FTC) significantly relieved central nervous system (CNS) toxicity and improved sleep in people with those problems while taking Atripla [1]. All but 1 of 40 study participants who switched in this London/Brighton study maintained virologic control through 24 weeks.

Published
16 September 2014
From
NATAP
Longer time to virological failure and less drug resistance seen in people taking Atripla than in people taking separate drugs

An analysis of people who experienced treatment failure on their first-line HIV therapy with a viral load of over 400 copies/ml and who had taken either

Published
09 September 2014
By
Gus Cairns
Switching from first-line ART with suppressed viral load linked to treatment failure

People who switch away from their initial antiretroviral therapy (ART) regimen when their viral load is undetectable may have a higher likelihood of subsequent virological failure, researchers reported

Published
29 July 2014
By
Liz Highleyman
Dolutegravir demonstrates good efficacy despite resistance

Antiretroviral regimens containing the recently approved HIV integrase inhibitor dolutegravir (Tivicay) demonstrated high rates of viral suppression even in treatment-experienced people who had virus with resistance to

Published
24 July 2014
By
Liz Highleyman
Therapy with newer, safer antiretrovirals an option for the majority of HIV-positive patients

The majority of people taking antiretroviral therapy (ART) that includes drugs associated with long-term side-effects may have the option of switching to a novel regimen

Published
11 July 2014
By
Michael Carter
Switch from single-tablet regimen to 3 tablets works in Denmark

Switching from an efavirenz-containing single-tablet regimen (STR) to an efavirenz containing triple-tablet regimen (TTR) to save money maintained viral suppression in Denmark. Antiretroviral-naive people who started the TTR attained the same virologic suppression rate as people who started the STR combination.

Published
10 July 2014
From
International AIDS Society
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