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Key points

  • HIV treatment works well for older people and viral load drops to an undetectable level quickly.
  • HIV treatment also helps protect against heart disease, cancer, kidney and liver disease.
  • Depending on other medications you may be taking and health issues, you may need dose adjustments.

Studies show that HIV treatment works well for older people. Viral load drops to an undetectable level (the aim of treatment) just as quickly as it does in younger people. Older people are often better than younger people at taking their medication as prescribed.

On the other hand, people who start treatment over the age of 50 may have a slower and less complete restoration of their immune system. The CD4 cell count doesn’t always rise as quickly as it does in younger adults.

As well as preventing HIV-related illnesses, effective HIV treatment helps protect against heart disease, cancer, kidney and liver disease. Among people living with HIV, rates of these conditions are lower in people who take HIV treatment than in people who do not.

Tailoring your treatment

If you have other health concerns as well as HIV, this can affect the choices you and your doctor make about which HIV drug combination is right for you.

Winnie Ssanyu Sseruma talks about ageing with HIV.

  • There could be interactions between one of your anti-HIV drugs and a medicine you take for another health condition. There’s more information on another page.
  • As you get older, your body may change. The liver and kidneys may work less efficiently, affecting the way a drug is processed in the body. Because of weight loss, decreased body fluid or increased fatty tissue, medicines may stay in the body longer and cause more side effects. Occasionally, your doctor may need to adjust your dose.
  • Some specific anti-HIV drugs are associated with a slightly increased risk of developing some health conditions, or could make a health condition worse for you. If this is the case, you will usually be able to take a different anti-HIV drug.

For these reasons, your choice of anti-HIV drugs may need to be tailored to your specific situation. You may need a different dose of one of your medicines. This may mean that a single tablet, which contains several drugs in fixed quantities, might not always be the right choice for you. You might need to switch from a drug combination that you have got used to.
 

Watch our aidsmapLIVE on HIV and ageing.

In the UK, standards for HIV treatment and care are set by the British HIV Association, the professional association for HIV doctors. Their guidelines recommend that doctors exercise caution in prescribing the following anti-HIV drugs to people who have specific health conditions or have risk factors for that condition.

Roger Pebody

Roger Pebody

Commissioning Editor

Roger joined aidsmap in 2008 and was Managing Editor from 2018 to 2024. As a freelancer, he now edits aidsmap’s news and conference coverage, as well as working on updates to About HIV pages. He is also a contributing science editor for TheBodyPro, a freelance journalist for The Lancet HIV, and a medical writer helping researchers prepare articles for peer-reviewed journals. He began working on HIV at Gay Men Fighting AIDS in the mid-1990s.

Basic information

How treatment works

How treatment works

Taking drugs on time

Taking drugs on time

Drug resistance

Drug resistance

Side effects

Side effects

Life expectancy

Life expectancy leaflet front cover

Antiretroviral drug chart

Antiretroviral drug chart

A to Z of antiretroviral medications

Starting HIV treatment

Pill in hand

Recommended treatments for HIV

A man in a blue t-shirt gets HIV treatment out of a blister pack.

One-pill-a-day HIV treatments

Image: carballo/Shutterstock.com

Anti-HIV drugs

Anti-HIV drugs booklet

Taking your HIV treatment

Taking your HIV treatment booklet

An introduction to HIV medicines

An introduction to HIV medicines

Blood tests before starting or changing HIV treatment

A close up of a person's arm while they are having their blood taken. The person taking the blood is wearing surgical gloves. We can see some of the blood is already in the tube.

Why taking your HIV treatment properly is important

Image: Domizia Salusest | www.domiziasalusest.com

Adherence to HIV treatment

Image: Domizia Salusest | www.domiziasalusest.com

Food requirements for anti-HIV medications

People sit outside at a table with a close up of a hand with pills in it.

HIV & women

Cover and inside spread of the HIV & women booklet.

Resistance to anti-HIV drugs

Image: Domizia Salusest | www.domiziasalusest.com

Changing HIV treatment

A man in a bathroom holding two bottles of medication and reading the label of one of them.

Side-effects of HIV treatment

An older man sitting in a chair with a blanket over his knees. He's resting his head on his hand.

Allergic reactions to HIV medications

Photoroyalty/Shutterstock.com

HIV treatment side-effects and mental health

Image: Domizia Salusest | www.domiziasalusest.com

Peripheral neuropathy and HIV

Image: Olena Yakobchuk/Shutterstock.com.

Lipodystrophy and HIV treatment

Flotsam/Shutterstock.com

Weight gain and HIV treatment

Shutterstock Studios HIV in View gallery

Life expectancy for people living with HIV

Mareike Günsche | www.aspect-us.com

HIV treatment breaks

A white pill bottle is tipped over with white pills spilling out on to a table.