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The search for a cure news


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Defective HIV proviruses hinder immune system response and cure

HIV proviruses can outnumber functional HIV 1000 copies to one and the faulty proteins they create can complicate efforts to measure a patient's viral load, exhaust immune systems, shield functional HIV from attack by natural means or drugs, and seriously complicate the development of a cure.

19 April 2017
Science Daily
Biomarker Opens New Door in HIV Cure Research

For the first time, investigators have found a biomarker that identifies some cells latently infected with HIV.

14 April 2017
MedPage Today HIV/AIDS
We asked a scientist to explain CRISPR to us—and how it’s being used in HIV research

Perhaps you’ve heard about a research technology called CRISPR (pronounced “crisper”) in the news. Since the technology was first developed, it has generated headlines as thousands of researchers have adopted this technology as a way to edit the genes of plant, animal and human cells.

12 April 2017
BETA blog
Research helps explain how vedolizumab antibody therapy leads to sustained viral remission

HIV and its monkey cousin SIV can carry the alpha-4 beta-7 integrin receptor in their outer envelope, which helps the virus enter gut cells during early infection,

23 March 2017
Liz Highleyman
Hidden HIV reservoirs exposed by telltale protein

The discovery helps to identify dormant infected cells and could one day lead to a cure.

21 March 2017
Monkeys suppress HIV-like virus for extended period after dual-antibody treatment

Giving monkeys two powerful anti-HIV antibodies immediately after infection with an HIV-like virus enabled the immune systems of some of the animals to control the virus long after the antibodies were gone, scientists at the National Institutes of Health and The Rockefeller University have found.

14 March 2017
Eurekalert Inf Dis
Researchers report case of bone marrow transplant patient off ART for 288 days without HIV rebound

An HIV-positive bone marrow transplant recipient at the Mayo Clinic experienced prolonged viral remission lasting nearly 10 months – longer than the so-called Boston patients – after interrupting

06 March 2017
Liz Highleyman
How to Keep HIV Cure-Related Trials Ethical: The Benefit/Risk Ratio Challenge

While high or unknown risks are a mainstay of early-phase trials in areas like cancer research, cure study participants typically have a safe and efficacious alternative to those risks: remaining on antiretrovirals. Can we justify asking patients who are doing well on antiretrovirals to accept the risk and uncertainty of many HIV cure-related trials? If we cannot, we might need to give up on the hope of curing HIV, or of achieving controlled remission.

22 February 2017
BMJ Blogs
Spanish vaccine induces viral control off ART in nearly 40% of recipients

A so-called ‘HIV Conserv’ vaccine has, for the first time, produced significant prolonged viral control in a large minority of recipients once they were taken off antiretroviral therapy

17 February 2017
Gus Cairns
Infants treated within days of birth can clear HIV reservoir rapidly

Viral load and viral DNA fall rapidly in infants who begin antiretroviral therapy (ART) within days of birth, two South African studies have found, showing the potential

15 February 2017
Keith Alcorn
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Community Consensus Statement on Access to HIV Treatment and its Use for Prevention

Together, we can make it happen

We can end HIV soon if people have equal access to HIV drugs as treatment and as PrEP, and have free choice over whether to take them.

Launched today, the Community Consensus Statement is a basic set of principles aimed at making sure that happens.

The Community Consensus Statement is a joint initiative of AVAC, EATG, MSMGF, GNP+, HIV i-Base, the International HIV/AIDS Alliance, ITPC and NAM/aidsmap

This content was checked for accuracy at the time it was written. It may have been superseded by more recent developments. NAM recommends checking whether this is the most current information when making decisions that may affect your health.

NAM’s information is intended to support, rather than replace, consultation with a healthcare professional. Talk to your doctor or another member of your healthcare team for advice tailored to your situation.