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Sharon Lewin appointed to lead Doherty Institute for Infection and Immunity

Leading infectious disease expert Professor Sharon Lewin has been appointed the inaugural Director of the Peter Doherty Institute for Infection and Immunity at the University of Melbourne.

Published
15 September 2014
From
Peter Doherty Institute
A "Bad Year" for HIV Cure Research? Experts Mix Realism and Hope

At ICAAC 2014, a major gathering of infectious disease experts, we heard speeches and spoke with leading HIV researchers about their evolving feelings regarding our fraught pathway toward a cure and the efforts currently underway to get us there.

Published
11 September 2014
From
The Body Pro
SIV Reservoir Fills Before Viremia in Rectally Infected Monkeys

In macaques rectally infected with simian immunodeficiency virus (SIV), the latent viral reservoir starts to fill with proviral DNA before viral RNA can be detected in peripheral blood. Findings from this study could help explain why HIV rebounded in the Mississippi child after being undetected for over 2 years.

Published
11 September 2014
From
International AIDS Society
Beyond the Berlin patient – seeking a cure for HIV-AIDS

Researchers from many corners of the world, including the Nobel Prize winning co-discoverer of the AIDS virus Françoise Barré-Sinoussi, are in Seattle this week to explore the possibility of curing people of HIV.

Published
28 August 2014
From
Humanosphere
HIV Antibodies Block Infection by Reservoir-Derived Virus in Laboratory Study

The researchers conclude that passive immunotherapy involving bNAbs individually or in combination may control HIV in the absence of antiretroviral therapy. A number of clinical trials are already underway or planned to test this hypothesis.

Published
27 August 2014
From
National Institutes of Allergy and Infectious Diseases press release
Novel immune-suppressant vaccine completely blocks HIV infection in monkeys: human trials planned

A novel and relatively simple vaccine that can be administered orally has managed to completely block rectal infection with SIV, the monkey equivalent of HIV, in rhesus

Published
26 August 2014
By
Gus Cairns
A voice for HIV cure: Scientists, activists gather for Hutch conference

Matt Sharp is no scientist. But when he joins researchers from around the country tomorrow for a conference on using gene therapy to cure HIV, he will bring a perspective that few others in the room can match.

Published
26 August 2014
From
Fred Hutchinson Cancer Research Center press release
Protein tethers HIV and Ebola to cells

A family of proteins that helps viruses, such as HIV and Ebola, enter a cell also can block the release of those viruses. When HIV-1 or any virus infects a cell, it replicates and spreads to other cells. One type of cellular protein—T cell immunoglobulin and mucin domain, or TIM-1—has previously been shown to promote entry of some highly pathogenic viruses into host cells. Researchers have now discovered that the same protein possesses a unique ability to block the release of such viruses. The findings are published in the Proceedings of the National Academy of Sciences. “This is a surprising finding that provides new insights into our understanding of not only HIV infection, but also that of Ebola and other viruses,” says Shan-Lu Liu, associate professor of molecular microbiology and immunology at University of Missouri.

Published
26 August 2014
From
Futurity
The Big Picture of Small Molecules for Curing HIV Infection

Dr. David Margolis and Karine Dubé of The Martin Delaney Collaboratory of AIDS Researchers for Eradication explain one strategy being pursued by scientists as a possible way to cure HIV. After reading this, if you want to learn more check out this video on related research.

Published
22 August 2014
From
AVAC
Vault nanoparticles engineered at UCLA show promise for cancer treatment and possible HIV cure

UCLA scientists developed a method for placing bryostatin 1 in nanoscale vaults for safe delivery to cells, where it can activate latent HIV, enabling the virus to be eradicated.

Published
22 August 2014
From
UCLA press release
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