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The search for a cure news

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How to Keep HIV Cure-Related Trials Ethical: The Benefit/Risk Ratio Challenge

While high or unknown risks are a mainstay of early-phase trials in areas like cancer research, cure study participants typically have a safe and efficacious alternative to those risks: remaining on antiretrovirals. Can we justify asking patients who are doing well on antiretrovirals to accept the risk and uncertainty of many HIV cure-related trials? If we cannot, we might need to give up on the hope of curing HIV, or of achieving controlled remission.

Published
22 February 2017
From
BMJ Blogs
Spanish vaccine induces viral control off ART in nearly 40% of recipients

A so-called ‘HIV Conserv’ vaccine has, for the first time, produced significant prolonged viral control in a large minority of recipients once they were taken off antiretroviral therapy

Published
17 February 2017
By
Gus Cairns
Infants treated within days of birth can clear HIV reservoir rapidly

Viral load and viral DNA fall rapidly in infants who begin antiretroviral therapy (ART) within days of birth, two South African studies have found, showing the potential

Published
15 February 2017
By
Keith Alcorn
Cake, candles and a wish for more HIV cures

An HIV workshop pays tribute to Timothy Ray Brown, whose cure 10 years ago fueled research — and hope

Published
14 February 2017
From
Fred Hutch
In the search for an HIV cure, David Evans explains “freedom” and how to better involve women & people of color

David Evans, director of research advocacy at Project Inform, talks about an ambitious HIV cure social science research project that will investigate some of the ethical and moral dilemmas cropping up in HIV cure research.

Published
09 February 2017
From
BETA blog
Study shows how HIV breaches macrophage defenses, could be step towards cure

A team led by UCL researchers identified how HIV is able to infect macrophages, a type of white blood cell, despite the presence of a protective protein. They discovered a treatment to maintain macrophage defenses that could help lead to an HIV cure.

Published
26 January 2017
From
EurekAlert (press release)
Gene Therapy to Cure HIV: Where to from Here?

In a commentary published in AIDS Patient Care and STDs, amfAR Vice President and Director of Research Dr. Rowena Johnston discusses what needs to be done to overcome the barriers to gene therapy to cure HIV, including increasing the effectiveness of gene editing, targeting it to the right cells in the body, and optimizing the length of time it stays in the body to safely achieve its goal.

Published
24 January 2017
From
amfAR
Is the Hope for a Miracle Cure Just Magical Thinking?

I can’t stop myself from hoping that someday we will see a miracle cure and HIV will be history. I know this isn’t realistic. But whenever I see a mention of a miracle cure, I can’t stop myself from checking it out. Always disappointing. Should I give up hope?

Published
23 January 2017
From
HIV Plus
Turning “off” these 3 genes would protect T cells from HIV

A team of researchers at the Ragon Institute of MGH, MIT and Harvard and the Broad Institute of MIT And Harvard have recently identified human genes that could be the key to a gene therapy-based HIV treatment.

Published
17 January 2017
From
BETA blog
Converging Roads Between HIV and Cancer Research

In 2017, a key focus in the field of HIV will be investigating new ways to tackle persistence via interactions and synergies with other fields such as cancer research and immune-based therapies. This will take centre stage when the scientific community convenes in July 2017 at the IAS HIV Cure & Cancer Forum and the 9th IAS Conference on HIV Science (IAS 2017).

Published
16 January 2017
From
International AIDS Society
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Community Consensus Statement on Access to HIV Treatment and its Use for Prevention

Together, we can make it happen

We can end HIV soon if people have equal access to HIV drugs as treatment and as PrEP, and have free choice over whether to take them.

Launched today, the Community Consensus Statement is a basic set of principles aimed at making sure that happens.

The Community Consensus Statement is a joint initiative of AVAC, EATG, MSMGF, GNP+, HIV i-Base, the International HIV/AIDS Alliance, ITPC and NAM/aidsmap
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This content was checked for accuracy at the time it was written. It may have been superseded by more recent developments. NAM recommends checking whether this is the most current information when making decisions that may affect your health.

NAM’s information is intended to support, rather than replace, consultation with a healthcare professional. Talk to your doctor or another member of your healthcare team for advice tailored to your situation.