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NIH Scientists Identify Potent Antibody that Neutralizes Nearly All HIV Strains

Scientists from the National Institutes of Health have identified an antibody from an HIV-infected person that potently neutralized 98 percent of HIV isolates tested, including 16 of 20 strains resistant to other antibodies of the same class. The remarkable breadth and potency of this antibody, named N6, make it an attractive candidate for further development to potentially treat or prevent HIV infection, say the researchers.

Published
17 November 2016
From
National Institute of Allergy and Infectious Diseases
J&J vaccine plus Gilead immune booster shows promise as HIV fighter

An experimental HIV vaccine from Johnson & Johnson combined with an immune system booster from Gilead Sciences Inc showed promise at keeping the virus at bay in monkeys even after treatments had stopped, marking yet another step toward the development of a so-called functional cure for HIV.

Published
10 November 2016
From
Reuters
Huge diversity in current HIV vaccine research, Research for Prevention conference hears

The HIV vaccine research field is currently going through probably its most fertile and diverse period yet, the second HIV Research for Prevention conference (HIVR4P) in Chicago

Published
23 October 2016
By
Gus Cairns
Gene therapy goes global: Portable device could make future cancer, HIV cures affordable

A tabletop device that enables medical staff to genetically manipulate a patient’s blood to deliver potential new therapies for cancer, HIV and other diseases would eliminate the need for multimillion-dollar “clean rooms,” making gene therapy more possible for even the poorest of countries.

Published
21 October 2016
From
Fred Hutchinson Cancer Research Center
HIV active in tissues of patients who were treated, study shows

UCSF researchers have found in autopsy tissue samples of patients treated with antiretrovirals that the virus evolved and migrated among tissues similar to the way it did in patients who had never received antiretroviral treatment, despite the fact that the treated patients had undetectable levels of virus in their blood.

Published
20 October 2016
From
Eurekalert Inf Dis
Crohn’s disease drug produces long-lasting viral undetectability and T-cell restoration off treatment in monkeys

In a promising experiment in rhesus macaque monkeys, scientists from Emory University in Atlanta have used a monkey-adapted version of vedolizumab (Entyvio), a drug used to treat gut

Published
14 October 2016
By
Gus Cairns
Antibody treatment surprisingly 'cures' monkeys of HIV-like infection

In Science today, a team led by immunologist Aftab Ansari of Emory University School of Medicine in Atlanta describes infecting eight monkeys with SIV, the simian version of HIV, treating them with ARVs, and then infusing them with an antibody similar to an approved drug for Crohn's disease and ulcerative colitis that targets a receptor on immune cell surfaces known as α4ß7.

Published
14 October 2016
From
Science
By adding an antibody to HIV treatment, researchers send virus into 'sustained remission' in monkeys

A clinical trial in monkeys found that by augmenting the standard HIV treatment with an antibody developed in the lab, the animals were able to enter a state of sustained remission, according to a report in Friday’s edition of the journal Science.

Published
14 October 2016
From
Los Angeles Times
HIV cure research: New animation explaining the RIVER study

Watch the animation to find out more about the RIVER study design. The study will report in 2018.

Published
11 October 2016
From
UK Cherub Collaboration
The Trauma of Hope: A Psychotherapist Reflects on False Cure News

This is the problem with news stories and headlines that are prematurely celebratory at best, and oversimplified, irresponsible and devastating at worst. For long-term survivors, hope triggers a particular kind of trauma made complicated by its relationship to grieving.

Published
10 October 2016
From
The Body PRO
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Community Consensus Statement on Access to HIV Treatment and its Use for Prevention

Together, we can make it happen

We can end HIV soon if people have equal access to HIV drugs as treatment and as PrEP, and have free choice over whether to take them.

Launched today, the Community Consensus Statement is a basic set of principles aimed at making sure that happens.

The Community Consensus Statement is a joint initiative of AVAC, EATG, MSMGF, GNP+, HIV i-Base, the International HIV/AIDS Alliance, ITPC and NAM/aidsmap
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This content was checked for accuracy at the time it was written. It may have been superseded by more recent developments. NAM recommends checking whether this is the most current information when making decisions that may affect your health.

NAM’s information is intended to support, rather than replace, consultation with a healthcare professional. Talk to your doctor or another member of your healthcare team for advice tailored to your situation.