Additional treatment costs arising from expanded HIV screening in US will place further pressure on Ryan White funding

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Expanded HIV screening programmes in the US will place additional pressure on Ryan White federal funding for HIV care as more people are diagnosed with HIV, according to a study published in the online edition of Value in Health.

Expanded testing is likely to identify more people with HIV in need of treatment. Treatment costs will mainly fall on discretionary programmes whose funding is set annually by Congress. The investigators express concern that this “may result in large numbers of individuals learning that they are HIV-infected but unable to receive care”.

It is estimated that 21% of the 1.1 million HIV-positive individuals in the US are unaware of their infection.

Glossary

Ryan White HIV/AIDS Program

In the United States, the largest federally funded programme providing HIV-related services to low-income, uninsured, and underinsured people with HIV/AIDS.

cost-effective

Cost-effectiveness analyses compare the financial cost of providing health interventions with their health benefit in order to assess whether interventions provide value for money. As well as the cost of providing medical care now, analyses may take into account savings on future health spending (because a person’s health has improved) and the economic contribution a healthy person could make to society.

Medicaid

In the United States, a programme providing health insurance to people on low-incomes of all ages. Provision varies from state to state, although some types of care are covered in all states.

Medicare

In the United States, a federal health insurance programme that guarantees health coverage for people aged 65 and over and some younger people with disabilities.

Undiagnosed people typically only learn that they have HIV when they are extremely ill with the virus, and this not only increases the risk of death but also has considerable cost implications. Moreover, some studies suggest that undiagnosed individuals are responsible for a large number of onward HIV transmissions.

In 2006, the US Centers for Disease Control and Prevention (CDC) issued revised guidance on HIV testing. This included a recommendation for routine HIV testing in all healthcare settings for the general population and annual HIV tests for those in high-risk groups.

The CDC calculated that this expansion of HIV testing would be cost-effective.

However, a team of investigators were concerned that the impact on government budgets was unclear. They especially wanted to see what the implications would be for discretionary HIV treatment programmes, whose fixed budgets are set annually.

There are a number of sources of public funding for HIV care in the US. These include the entitlement programmes Medicaid and MediCare. These provide free healthcare to the 'disabled' and the elderly. There is also the discretionary Ryan White HIV/AIDS Program. This provides a safety net for those who neither qualify for the eligibility programmes, nor have adequate private insurance.

Treatment and care costs for ex-military personnel are met by the Department of Veterans Affairs, and others have adequate private medical insurance. The investigators did not examine the likely cost implications of earlier HIV diagnosis for these care providers.

The investigators’ model was based on 2008 HIV surveillance data. This showed that there were 1.1 million HIV-positive individuals in the US, but that 189,000 of these were unaware of their status. Annual HIV incidence was assumed to be 46,000.

Data concerning the health and CD4 cell count of prevalent cases of HIV were extrapolated from surveillance cohorts.

Costs were assumed to include the testing of individuals whose results were HIV-negative and those who were positive, with the latter group requiring post-test counselling. Currently 97% of individuals return for their HIV test result, and 80% of those testing positive are linked to care. This pattern of behaviour was included in the model. Drug costs were calculated using published wholesale costs. These were adjusted for average state reimbursement rates and discounts.

It was estimated that individuals currently have an HIV test every ten years. The model assumed that expanded testing would mean that individuals would now be tested every five years.

The model suggested that if average testing frequency remained once every ten years, then there would be 177,000 new HIV diagnoses between 2009 and 2013. This figure included 116,000 individuals with undiagnosed HIV and 61,000 newly infected with the virus.

After diagnosis, 68% of those diagnosed late and 49% of people with incident infections were expected to progress to AIDS.

Increasing the frequency of testing to once every five years would lead to an additional 46,000 new diagnoses. But earlier detection of HIV would lead to a fall in the number of those who progressed to AIDS.

Continued testing at the current rate was estimated to cost $83.7 billion over five years. Expanded testing and increases in the number of diagnosed patients would increase this to $86.4 billion.

Only 18% of this additional cost  ($502 million) was attributed to screening programmes. The rest was taken up by treatment and care.

The investigators projected that the cost to discretionary programmes would increase by $2.9 billion (from $26 billion to $28.9 billion). However, because there would be a fall in the number of patients progressing to AIDS, costs to entitlement programmes would fall by $280 million.

This meant that then an additional $2.7 billion would be needed for screening and treatment programmes, with most falling on discretionary treatment programmes.

“If expanded screenings were implemented consistent with CDC guidelines, the policy may not be feasible without additional funds from state and local governments,” comment the authors. The cost burden “will fall disproportionately on discretionary programs, because people identified will be less likely to be immediately eligible for entitlement programs”.

References

Martin EG et al. Expanded HIV screening in the United States: what will it cost government discretionary and entitlement programs? A budget impact analysis. Value in Health, online edition, 2010 (click here for the free abstract).