Detailed information
Teaser

Stribild is a single-tablet regimen, combining emtricitabine, tenofovir disoproxil fumarate, elvitegravir and cobicistat in one pill, taken once a day.

Basic information
Legacy Id
2954943
Drug interactions

If you are taking Stribild it’s important to check with your HIV doctor or pharmacist before taking any medicines from the following groups: antibiotics; antiepileptic medicines; medication to treat high blood pressure; medication to treat high cholesterol (e.g. statins); antidepressants; anticoagulants (medication to thin the blood); medication to help sleep or for sedation; metformin (a tablet to treat diabetes); antiarrhythmic medication (for irregular heart rhythm); oral contraceptives (birth control); steroids taken by inhaler or nasal spray (some steroids can build up in the body causing serious side-effects and must not be taken with Stribild. Check before using any steroids in this way); herbal medicines (in particular St John’s Wort should be avoided); erectile dysfunction agents (some of these can be increased to dangerous levels and a decreased dose may be recommended).

Taking calcium, iron, magnesium or aluminium can stop you from absorbing Stribild properly – all multivitamin and mineral supplements and antacids must be taken at least 4 hours before or after Stribild.

Resistance

Not suitable for people with resistance to raltegravir or elvitegravir.

Rare side effects

Lactic acidosis (too much lactic acid in the blood), kidney failure.

Common side effects

Nausea, diarrhoea, vomiting, abnormal dreams, headache, fatigue, dizziness, insomnia, rash, itching, abdominal pain, bloating, flatulence, constipation, sleepiness, weakness, skin darkening, low white blood cell count, low blood phosphate levels, raised triglyceride and blood sugar levels, and raised liver enzyme, amylase, creatinine or creatine kinase levels. 

Tips on taking it

Take with food. If you take Stribild without food you may not absorb enough elvitegravir and your treatment may fail.

Approved dosage

Combination treatment in one tablet, taken once a day. Combines 200mg of emtricitabine, 245mg of tenofovir disoproxil (both NRTIs) and 150mg of elvitegravir (an integrase inhibitor), along with 150mg cobicistat (a boosting agent), in a green film-coated tablet.

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