Maraviroc is marketed under the name Celsentri. It is taken in combination with other antiretroviral drugs.

If you are taking any of the following drugs, the dose of maraviroc may have to be changed: antibiotics (clarithromycin, telithromycin, rifampicin, rifabutin); antifungal medicines (ketoconazole, itraconazole, fluconazole); anticonvulsant medicines (carbamazepine, phenytoin, phenobarbital).

Dose adjustment needed when maraviroc is taken with some other anti-HIV drugs.

St John's wort should not be taken with maraviroc.

Resistance to maraviroc is still being studied and appears to occur in a different way to other anti-HIV drugs.

Liver problems, allergic (hypersensitivity) reaction including itchy rash, yellowing of the eyes, vomiting, dark urine and abdominal pain on the right side.

Postural hypotension (dizziness on standing too quickly), anaemia, nausea, diarrhoea, abdominal pain, bloating, loss of appetite, flatulence, weakness, depression, difficulty in sleeping, raised liver enzyme levels, rash. 

Take the dose with or without food.

The dose of maraviroc is dependent on the other anti-HIV drugs you take. Your HIV doctor or pharmacist will talk to you about which dose is appropriate for you. Most people will take one blue tablet (300mg or 150mg) twice daily.

Maraviroc should only be used by people with a type of HIV called CCR5-tropic HIV. Not everybody has this type of virus; if you do not have it, you should not take maraviroc. Your HIV clinic should carry out a test called a tropism test to see if you have CCR5-tropic HIV before prescribing the drug.