Genvoya is a single-tablet regimen combining elvitegravir, cobicistat, emtricitabine and tenofovir alafenamide in one pill, taken once a day.

If you are taking Genvoya it’s important to check with your HIV doctor or pharmacist before taking any medicines from the following groups: antibiotics; antiepileptic medicines; medication to treat high blood pressure; medication to treat high cholesterol (e.g. statins); antidepressants; anticoagulants (medication to thin the blood); medication to help sleep or for sedation; metformin (a tablet to treat diabetes); antiarrhythmic medication (for irregular heart rhythm); oral contraceptives (birth control); steroids taken by inhaler or nasal spray (some steroids can build up in the body causing serious side-effects and must not be taken with Genvoya. Check before using any steroids in this way); herbal medicines (in particular St John’s Wort should be avoided); erectile dysfunction agents (some of these can be increased to dangerous levels and a decreased dose may be recommended).

The antibiotics used to treat TB, rifampicin and rifabutin, may reduce levels of tenofovir alafenamide; so may some anticonvulsants including phenytoin and phenobarbital.

Taking calcium, iron, magnesium or aluminium can stop you from absorbing Genvoya properly – all multivitamin and mineral supplements and antacids must be taken at least 4 hours before or after Genvoya.

Not suitable for people with resistance to raltegravir or elvitegravir.

Depression, swelling of the skin, face, lips, tongue or throat.

Abnormal dreams, headache, dizziness, nausea, diarrhoea, vomiting, abdominal pain, flatulence, rash and tiredness.

Take with food. If you take Genvoya without food you may not absorb enough elvitegravir and your treatment may fail.

Combination treatment in one tablet, taken once a day. Combines 150mg elvitegravir (an integrase inhibitor), 200mg emtricitabine and 10mg of tenofovir alafenamide (both NRTIs), along with 150mg cobicistat (a boosting agent) in a green film-coated tablet.