Detailed information
Teaser

Descovy combines emtricitabine and tenofovir alafenamide in one pill. It is taken in combination with other antiretroviral drugs.

Basic information
Alternative names
emtricitabine/tenofovir alafenamide
Drug interactions

You should not take Descovy with any of the following drugs, used to treat hepatitis B: tenofovir disoproxil fumarate, lamivudine, adefovir dipivoxil.

The antibiotics used to treat tuberculosis (TB), rifampicin and rifabutin, may reduce levels of tenofovir alafenamide.

There are other interactions, including with common drugs such as some antibiotics, antivirals used to treat hepatitis C, anticonvulsants used to treat epilepsy and the herbal remedy St John’s wort, so it is very important that you tell your doctor about other drugs you are taking.

Rare side effects

Anaemia, swelling of the skin, face, lips, tongue or throat.

Common side effects

Headache, dizziness, abnormal dreams, nausea, vomiting, diarrhoea, abdominal pain, flatulence, indigestion, rash, tiredness.

Tips on taking it

Take with or without food.

The pill containing 10mg of tenofovir alafenamide should only be taken if combined with the boosters ritonavir or cobicistat. The pill containing 25mg of tenofovir alafenamide should be taken with all other third agents, e.g. etravirine, raltegravir, efavirenz, dolutegravir.

Approved dosage

Combination tablet of 200mg emtricitabine and either 10mg (grey tablet) or 25mg (blue tablet) of tenofovir alafenamide. The usual adult dose is one tablet taken once a day.

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