Delstrigo is a single-tablet regimen, combining doravirine, lamivudine and tenofovir disoproxil fumarate in one pill, taken once a day.

You should not take Delstrigo if you are currently taking products that contain St John’s wort (a herbal remedy used for depression and anxiety); carbamazepine, oxcarbazepine, phenobarbital and phenytoin (used to treat epilepsy and prevent seizures); rifampicin and rifapentine (used to treat some bacterial infections such as TB); mitotane (a cancer treatment); enzalutamide (a treatment for prostate cancer); lumacaftor (treatment for cystic fibrosis); nafcillin (an antibiotic); telotristat ethyl (diarrhoea treatment); lesinurad (anti-gout treatment); bosentan (blood pressure treatment); dabrafenib (skin cancer treatment); modafinil (used to treat severe sleep disorders, chronic drowsiness).

Lactic acidosis, suicidal thoughts, hepatitis, acute kidney failure or damage.

Abnormal dreams, difficulty in sleeping, nightmare, depression, headache, dizziness, drowsiness, cough, an irritated or runny nose, nausea, diarrhoea, abdominal pain, vomiting, hair loss, rash, muscle disorders, fatigue, fever.

Take with or without food.

Triple-drug combination in one tablet, taken once a day. Combines 100mg of doravirine (an NNRTI), 300mg of lamivudine and 245mg of tenofovir disoproxil (both NRTIs) in a yellow tablet.