Cobicistat is used to boost the effects of protease inhibitors. It is marketed under the name Tybost.

As a boosting agent, cobicistat can also interact with other medicines. Check specific drug interaction information by choosing the drugs in your regimen using this tool.

Cobicistat should not be used with alfusozin, ranolazine, dronedarone,carbamazepine, phenobarbital, phenytoin, rifampicin, lurasidone pimozide, dihydroergotamine, ergotamine, cisapride, lovastatin, simvastatin, triazolam or oral midazolam.

Kidney stones.

Raised blood sugar, increased appetite, difficulty in sleeping, drowsiness, abnormal dreams, headache, dizziness, altered sense of taste, nausea, diarrhoea, abdominal pain, bloating, flatulence, dry mouth, jaundice, rash, and tiredness.

Take with food.

The usual adult dose is one 150mg round, yellow tablet taken once a day to boost darunavir or atazanavir. Cobicistat is also available in the following combination drugs: Symtuza, Genvoya, Stribild, Evotaz, Rezolsta.