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Case Western Reserve and Sangamo Therapeutics Announce $11 Million NIH Grant for Study of Gene-Edited T Cells for Viral Eradication of HIV

The grant will fund a clinical trial to test the hypothesis that treating patients with their own gene-edited T cells may lead to a sustained increase in T cell counts and eradication of latent HIV reservoirs.

Published
07 February 2018
From
Sangamo press release
What does an HIV cure mean to you?

We did a study to better understand the meanings of HIV cure among people living with HIV. This is critical to reconcile what would be clinically feasible with what would be meaningful for people living with HIV.

Published
06 February 2018
From
Positively Aware
Update from HIV Persistence 2017

The 8th biennial HIV Persistence during Therapy Workshop was held in Miami, FL from December 12 – 15, 2017. This meeting has become the reference workshop on HIV reservoir and elimination strategies. Below are some highlights from the meeting.

Published
31 January 2018
From
Positively Aware
Lung Cancer Treatment May Successfully Deplete HIV Reservoir

Nivolumab treatment for non-small-cell lung cancer may induce successful depletion of HIV reservoir, according to a letter to the editor published in the Annals of Oncology.

Published
30 January 2018
From
Infectious Disease Advisor
Researchers find latent HIV reservoirs inherently resistant to elimination by CD8+ T-cells

A research team at GW School of Medicine and Health Sciences found that latent HIV reservoirs exhibit resistance to elimination by CD8+ T-cells.

Published
23 January 2018
From
Eurekalert Inf Dis
NIH study supports use of short-term HIV treatment interruption in clinical trials

A short-term pause in HIV treatment during a carefully monitored clinical trial does not lead to lasting expansion of the HIV reservoir nor cause irreversible damage to the immune system, new findings suggest.

Published
11 January 2018
From
National Institutes of Health
Selective suppression of inflammation could deplete HIV and control HIV activation

A class of anti-inflammatory drugs already FDA-approved for rheumatoid arthritis could "purge" the reservoir of infected immune cells in people infected by HIV, according to new research.

Published
02 January 2018
From
Emory University
Preliminary study hints that genetically modified T cells might fight HIV

The same kind of DNA tinkering that produced the first FDA-approved gene therapy for cancer has shown hints of suppressing and even eradicating HIV infection in lab animals, scientists have reported. Although the study was small — it tested the genetically engineered “CAR” cells on only two monkeys as well as on cells growing in lab dishes — it suggests that after 30 years of fruitless efforts to come up with an AIDS vaccine there might be a wholly new way to get the immune system to fight HIV infection.

Published
02 January 2018
From
STAT
Could a virus kill HIV? Ottawa research shows promise

A virus being tested as a potential cancer treatment is showing promise for the treatment of human immunodeficiency virus (HIV), according to a study by a team of Ottawa researchers.

Published
20 December 2017
From
CBC.ca
Frontiers of HIV Research: The Man Who Was Nearly Cured

“The whole excitement around Clark is that we were able to initiate therapy so early that we were hoping to prevent the establishing of latency,” says Deeks. “But it did not happen. We got close; we may have been off by a day or two. We did not achieve a real cure.”

Published
13 December 2017
From
KQED
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Community Consensus Statement on Access to HIV Treatment and its Use for Prevention

Together, we can make it happen

We can end HIV soon if people have equal access to HIV drugs as treatment and as PrEP, and have free choice over whether to take them.

Launched today, the Community Consensus Statement is a basic set of principles aimed at making sure that happens.

The Community Consensus Statement is a joint initiative of AVAC, EATG, MSMGF, GNP+, HIV i-Base, the International HIV/AIDS Alliance, ITPC and NAM/aidsmap
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This content was checked for accuracy at the time it was written. It may have been superseded by more recent developments. NAM recommends checking whether this is the most current information when making decisions that may affect your health.

NAM’s information is intended to support, rather than replace, consultation with a healthcare professional. Talk to your doctor or another member of your healthcare team for advice tailored to your situation.