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Sleep Abnormalities Do Not Reverse After Discontinuing Efavirenz

For patients with HIV receiving efavirenz-based therapy, sleep and neuropsychological abnormalities do not readily reverse after discontinuation of treatment, according to results published in HIV Clinical Trials.

Published
14 January 2019
From
Infectious Disease Advisor
Efavirenz Likely Safe for Pregnant HIV-Positive Women

The prevalence of birth defects following use of efavirenz (EVF)-based antiretroviral therapy (ART) is not statistically different from non-EFV-based ART during conception or in the first trimester, researchers say.

Published
09 January 2019
From
Medscape (requires free registration)
Top 10 HIV Clinical Developments of 2018

It's the beginning of the end. Not in some apocalyptic way, but rather in how we think about the prevention and management of HIV.

Published
20 December 2018
From
The Body Pro
What triggered my heart attack?

Jackie Morton, ex-Chair of the European AIDS Treatment Group, found her severe pain was due to a heart attack. Here she writes a detailed, dispassionate and scientific blog on the possible causes - and remedies.

Published
19 November 2018
From
EATG
Cardiovascular Risk Unclear for HIV Patients on Dolutegravir

Patients with HIV who switched to a dolutegravir-based regimen from a ritonavir-boosted protease inhibitor regimen experienced body mass gain and changes in biomarkers related to increased insulin resistance, according to a subanalysis of the NEAT 022 study.

Published
01 November 2018
From
Medscape (requires free registration)
Dolutegravir Use During Pregnancy: What Are the Risks?

Infectious Disease Advisor spoke to Rebecca M. Zash, MD, a co-investigator of the interim analysis by the Tsepamo Study in Botswana, which was published in the New England Journal of Medicine in July.

Published
22 October 2018
From
Infectious Disease Advisor
Efavirenz in HIV-positive pregnant women, risk of neurological condition in children

Researchers found children of women whose ART regimen included efavirenz were 60 percent more likely to develop a neurological condition, such as microcephaly (small head), seizures (from a high fever or other cause) and eye abnormalities than children whose mothers took other ART medications.

Published
05 October 2018
From
IDSA press release
Why the world may force women to choose: No birth control, no ARVs

A new drug could save 25 000 women living with HIV but could it come at the cost of their babies lives?

Published
22 August 2018
From
Bhekisisa
Dolutegravir preconception signal: time is up for shoddy surveillance

The news in May 2018 of a potential risk of neural tube defects in infants born to women taking dolutegravir (DTG) at the time of conception sent shockwaves through the HIV community. But, despite massive global investment, aggressive transition plans – as well as calls for years for more systematic recording of outcomes when women receive ART in pregnancy– few prospective birth registrieshave been established in other settings that can refute or confirm this finding. Meanwhile, women of child-bearing age, whether they intend to become pregnant or not, are being told that they must stick with (or go back to) efavirenz (EFV) – a drug that, before this news, was in the process of being replaced with DTG.

Published
16 July 2018
From
HIV i-Base
We Must Talk About Having Diarrhea. I’ll Go First.

My discomfort discussing anything butt-related is well documented, but this is important. Here’s why. One in five people living with HIV suffers from chronic diarrhea. That’s too many, and I happen to be one of them. Many of us figure that if the meds are working and we’re healthy, then gastrointestinal problems simply come with the territory. Remember the HIV drug Kaletra? What a nightmare.

Published
16 July 2018
From
My Fabulous Disease
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Community Consensus Statement on Access to HIV Treatment and its Use for Prevention

Together, we can make it happen

We can end HIV soon if people have equal access to HIV drugs as treatment and as PrEP, and have free choice over whether to take them.

Launched today, the Community Consensus Statement is a basic set of principles aimed at making sure that happens.

The Community Consensus Statement is a joint initiative of AVAC, EATG, MSMGF, GNP+, HIV i-Base, the International HIV/AIDS Alliance, ITPC and NAM/aidsmap
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This content was checked for accuracy at the time it was written. It may have been superseded by more recent developments. NAM recommends checking whether this is the most current information when making decisions that may affect your health.

NAM’s information is intended to support, rather than replace, consultation with a healthcare professional. Talk to your doctor or another member of your healthcare team for advice tailored to your situation.