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Transition to dolutegravir cost-effective in LMICs with high HIV drug resistance

In low- and middle-income countries, resistance to non-nucleoside reverse transcriptase inhibitors, or NNRTIs, is nearing and exceeding 10% in patients with HIV who are initiating or reinitiating first-line ART, according to recent data. A new modeling study showed that transitioning first-line ART from NNRTIs to dolutegravir may be a cost-effective way to reverse this increasing trend in resistance.

Published
13 December 2017
From
Healio
Rising levels of HIV drug resistance

HIV drug resistance is approaching and exceeding 10 percent in people living with HIV who are about to initiate or reinitiate first-line antiretroviral therapy, according to the largest meta-analysis to date on HIV drug resistance, led by researchers at UCL and the World Health Organization (WHO) and funded by the Bill & Melinda Gates Foundation and the WHO.

Published
01 December 2017
From
Eurekalert Inf Dis
BASHH welcomes publication of position statement on doxycycline as post-exposure prophylaxis for sexually transmitted infections

The British Association for Sexual Health and HIV (BASHH) has welcomed the publication of a new joint BASHH and Public Health England (PHE) position statement on the use of doxycycline as post-exposure prophylaxis (PEP) for sexually transmitted infections (STIs). A conference presentation had suggested that use of PEP with doxycycline was associated with a halving of the rates of bacterial STIs in men who have sex with men (MSM), in an extension of the French IPERGAY trial. However caution is advised.

Published
03 November 2017
From
BASHH
Uganda: ARVs Stock-Out Sparks Fear of Mass Drug Resistance

Civil society organisations and people living with HIV/Aids have warned that almost a million Ugandans could develop resistance to first-line anti-retroviral therapy if nothing is done about the nation-wide stock-out of drugs.

Published
01 November 2017
From
AllAfrica
Antibody-Based HIV Tx Proves Durable

The monoclonal antibody HIV drug ibalizumab, designed for patients who've developed severe drug resistance, had long-lasting protection in the 24-week extension phase of a phase III trial, researchers reported here.

Published
10 October 2017
From
MedPage Today
HIV drug resistance found in more than half of young children in Africa

Approximately 54% of young children with HIV surveyed in Africa had resistance to one or more antiretroviral drugs, according to recent data.

Published
24 August 2017
From
Healio
A massive second global wave of AIDS is coming — perhaps within the next 10 years

Three problems are driving the global fight against HIV into a new danger zone. First, new infections increasingly involve forms of the virus that are already resistant to the primary drugs used to treat and prevent HIV infection. Second, the world is fast approaching the limits of manufacturing capacity for anti-HIV first-line drugs, and the ceiling is far lower for second- and third-line treatments. And third, there aren’t sufficient financial resources applied to the AIDS problem now, and signals from major donors — especially the U.S. government — offer a grim future of diminished resources and greater demands on very poor countries to finance their own HIV fights without outside help.

Published
31 July 2017
From
Business Insider
WHO urges action against HIV drug resistance threat

WHO alerts countries to the increasing trend of resistance to HIV drugs detailed in a report based on national surveys conducted in several countries. The Organization warns that this growing threat could undermine global progress in treating and preventing HIV infection if early and effective action is not taken.

Published
20 July 2017
From
World Health Organization
Oral sex spreading unstoppable bacteria

Oral sex is producing dangerous gonorrhoea and a decline in condom use is helping it to spread, the World Health Organization has said. Gonorrhoea can infect the genitals, rectum and throat, but it is the last that is most concerning health officials. Dr Wi said antibiotics could lead to bacteria in the back of the throat, including relatives of gonorrhoea, developing resistance. She said: "When you use antibiotics to treat infections like a normal sore throat, this mixes with the Neisseria species in your throat and this results in resistance."

Published
07 July 2017
From
BBC
Experts raise concerns over high HIV treatment failure in Kenya

Local and international health authorities are concerned about emerging evidence of high HIV treatment failure in Kenya. The latest findings in a report by the Ministry of Health and the UN published last week spoke of "unacceptably" high failure rates of Anti-retrovirals (ARVs) among refugees and residents of Kakuma in northern Kenya.

Published
06 June 2017
From
The Standard
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Community Consensus Statement on Access to HIV Treatment and its Use for Prevention

Together, we can make it happen

We can end HIV soon if people have equal access to HIV drugs as treatment and as PrEP, and have free choice over whether to take them.

Launched today, the Community Consensus Statement is a basic set of principles aimed at making sure that happens.

The Community Consensus Statement is a joint initiative of AVAC, EATG, MSMGF, GNP+, HIV i-Base, the International HIV/AIDS Alliance, ITPC and NAM/aidsmap
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This content was checked for accuracy at the time it was written. It may have been superseded by more recent developments. NAM recommends checking whether this is the most current information when making decisions that may affect your health.

NAM’s information is intended to support, rather than replace, consultation with a healthcare professional. Talk to your doctor or another member of your healthcare team for advice tailored to your situation.