Nevirapine (Viramune)

Nevirapine (Viramune) is an anti-HIV drug that reduces the amount of virus in the body. Anti-HIV drugs such as nevirapine slow down damage to the immune system and prevent the occurrence of AIDS-defining illnesses .

Nevirapine belongs to a class of drugs known as non-nucleoside reverse transcriptase inhibitors (NNRTIs) . The enzyme reverse transcriptase converts single-stranded viral RNA into DNA. Drugs in the NNRTI class stop HIV from replicating within cells by binding near reverse transcriptase’s active site and inhibiting polymerase activity.

Formerly known by the codename BI-RG-587, nevirapine is manufactured by Boehringer Ingelheim under the trade name Viramune. Nevirapine was licensed in the European Union in February 1998, and in the United States in June 1996.