A to Z of antiretroviral drugs

Prior to using a new medication, there are certain issues that should be discussed before the first dose is taken. This should include a clear understanding of the following:

  • The reasons for selecting a particular treatment regimen.
  • A drug/regimen's past efficacy and expected treatment outcomes.
  • All dosing issues, including how a medication is taken, how often, how much, and when.
  • Likely and/or potential treatment side-effects.
  • An awareness of the difference between an 'expected' reaction and a severe adverse reaction that merits checking in with the clinic.
  • Possible interactions with other drugs the person is already taking.

Knowing in advance that a drug often causes a certain reaction (for instance, headache, rash, or stomach pain) to some extent prepares someone to handle the problem. Generally, the fewer surprises involved, the better it is for everyone involved.

  • 3TC (lamivudine, Epivir)

    Information on 3TC (lamivudine, Epivir), including dosing, effectiveness, side-effects, resistance and drug interactions.

  • Abacavir (Ziagen)

    Abacavir is an anti-HIV drug that reduces the amount of virus in the body. Anti-HIV drugs such as abacavir slow down or prevent damage to

  • Atazanavir (Reyataz)

    Information on the protease inhibitor atazanavir (Reyataz), including its effectiveness, side-effects and drug interactions.

  • Atripla

    Atripla is a fixed-dose tablet combining 600mg efavirenz, 200mg FTC (emtricitabine), and 245mg tenofovir, manufactured jointly by Bristol-Myers Squibb and Gilead Sciences. Efavirenz is a non-nucleoside reverse

  • AZT (zidovudine, Retrovir)

    Information on AZT (zidovudine, Retrovir), including its effectiveness, side-effects, drug interactions and use in pregnant women and children.

  • Combivir (AZT/3TC)

    Combivir is a fixed-dose combination tablet comprising 150mg 3TC (lamivudine) and 300mg AZT (zidovudine) manufactured by GlaxoSmithKline. AZT and 3TC are both nucleoside reverse transcriptase

  • d4T (stavudine, Zerit)

    d4T (stavudine, Zerit) is an anti-HIV drug that reduces the amount of virus in the body. Anti-HIV drugs such as d4T slow down or prevent

  • Darunavir (Prezista)

    Information on the protease inhibitor darunavir.

  • ddI (didanosine, Videx/VidexEC)

    ddI (didanosine, Videx/VidexEC) is an anti-HIV drug that reduces the amount of virus in the body. Anti-HIV drugs such as ddI slow down or prevent

  • Delavirdine (Rescriptor)

    Delavirdine is a non-nucleoside reverse transcriptase inhibitor (NNRTI). The enzyme reverse transcriptase converts single-stranded viral RNA into DNA. Drugs in the non-nucleoside reverse transcriptase inhibitor

  • Efavirenz (Sustiva)

    Efavirenz (Sustiva) is an anti-HIV drug that reduces the amount of virus in the body. Anti-HIV drugs such as efavirenz slow down damage to the

  • Enfuvirtide (T-20, Fuzeon)

    Information on T-20 (Fuzeon), including effectiveness, side-effects, resistance and its use in children and pregnant women.

  • Etravirine (Intelence)

    Etravirine (Intelence) is an anti-HIV drug that reduces the amount of virus in the body and belongs to the class of drugs known as non-nucleoside reverse transcriptase

  • Eviplera

    Eviplera is a fixed-dose tablet combining 25mg rilpivirine, 200mg FTC (emtricitabine), and 245mg tenofovir, manufactured jointly by Johnson & Johnson/Tibotec and Gilead Sciences. Rilpivirine is a non-nucleoside

  • Fosamprenavir (Telzir, Lexiva)

    Fosamprenavir (Telzir) is an anti-HIV drug that reduces the amount of virus in the body. Anti-HIV drugs such as fosamprenavir slow down or prevent damage

  • FTC (emtricitabine, Emtriva)

    FTC (emtricitabine, Emtriva) is an antiviral drug that reduces the amount of HIV in the body. Anti-HIV drugs such as FTC slow down or prevent

  • Indinavir (Crixivan)

    Indinavir (Crixivan) is an anti-HIV drug that reduces the amount of virus in the body. Anti-HIV drugs such as indinavir slow down or prevent damage

  • Kivexa (abacavir/3TC)

    Kivexa (Epzicom) is a fixed-dose combination tablet combining 300mg 3TC (lamivudine) and 600mg abacavir, manufactured by GlaxoSmithKline. Abacavir and 3TC are both nucleoside reverse transcriptase inhibitors (NRTIs). The standard

  • Lopinavir/ritonavir (Kaletra)

    Lopinavir/ritonavir (Kaletra, Aluvia) is a protease inhibitor drug available in tablet and solution form. Lopinavir is marketed only with a boosting dose of ritonavir; ritonavir is marketed separately as Norvir.

  • Maraviroc (Celsentri)

    Maraviroc (known by the trade name Celsentri in Europe and Selzentry in the United States) is the first drug to be licensed from a new class

  • Nelfinavir (Viracept)

    Nelfinavir is a protease inhibitor, an anti-HIV drug that reduces the amount of virus in the body. Anti-HIV drugs such as nelfinavir slow down or prevent

  • Nevirapine (Viramune)

    Nevirapine (Viramune) is an anti-HIV drug that reduces the amount of virus in the body. Anti-HIV drugs such as nevirapine slow down damage to the immune

  • Raltegravir (Isentress)

    Raltegravir (Isentress) is an HIV-1 integrase strand-transfer inhibitor with potent antiretroviral activity. It belongs to a new class of antiretrovirals called integrase inhibitors. The drug works

  • Rilpivirine (Edurant)

    Rilpivirine (Edurant), previously known as TMC278) is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI), developed by Johnson & Johnson/Tibotec. Rilpivirine was submitted for licensing in

  • Ritonavir (Norvir)

    Ritonavir (Norvir) is a protease inhibitor, an anti-HIV drug that reduces the amount of virus in the body. Anti-HIV drugs such as ritonavir slow down or prevent

  • Saquinavir (Invirase)

    Information on saquinavir (Invirase / Fortovase), including efficacy, boosting with ritonavir (Norvir), side-effects, resistance, drug interactions and the treatment of children and pregnant women.

  • Tenofovir (Viread)

    Tenofovir (Viread) is an antiviral drug that is approved for the treatment of HIV infection. It is able to reduce the amount of HIV in

  • Tipranavir (Aptivus)

    Information on tipranavir (Aptivus), including dosing, availability, effectiveness and drug resistance.

  • Triomune

    Triomune is a co-formulation of three drugs commonly used in the management of HIV infection. It contains generic versions of the nucleoside reverse transcriptase inhibitors lamivudine (3TC) and

  • Trizivir (AZT/3TC/abacavir)

    Trizivir is a fixed-dose combination tablet containing 150mg 3TC (lamivudine, Epivir), 300mg abacavir and 300mg AZT (zidovudine, Retrovir). It is manufactured by GlaxoSmithKline. 3TC, abacavir and AZT are

  • Truvada (tenofovir/FTC)

    Truvada is a fixed-dose combination tablet combining 200mg FTC (emtricitabine) and 245mg tenofovir. It is manufactured by Gilead Sciences. FTC is a nucleoside reverse transcriptase inhibitor (NRTI)