An 8-week course of sofosbuvir/ledipasvir (Harvoni) led to a sustained response in all people with HIV and genotype 1 or 4 hepatitis C virus (HCV) in the SWIFT-C study, according to a report at the AASLD Liver Meeting in Washington, DC.
Physicians in the United States are less likely to prescribe key recommended medications for the prevention of cardiovascular disease to people with HIV compared to HIV-negative individuals, according to research published in the Journal of the American Heart Association. Prescription rates for aspirin, antiplatelet medications and statins were markedly lower for people with HIV, all of whom presented with symptoms or risk factors for cardiovascular disease.
People with HIV who are undiagnosed and those with detectable viral load less likely to use condoms, South African study finds
People with HIV who don't use condoms consistently are more likely to be unaware they are HIV-positive or to have a detectable viral load when their HIV infection has been diagnosed, according to research conducted in South Africa and published in Nature Scientific Reports.
HIV-positive transgender men in the United States have significant unmet social and healthcare needs, according to a study published in Research and Practice. Approximately half were living in poverty and only 60% had sustained viral suppression.
HIV drug resistance now high enough to trigger a change in first-line treatment in eastern and southern Africa
HIV drug resistance is increasing rapidly in southern and eastern Africa and Latin America and, as a result, it may soon be necessary to change the recommended first-line antiretroviral drug regimen in many countries to integrase inhibitor-based treatment, according to an analysis published in The Lancet Infectious Diseases on 30 November.
ART reduces prevalence of cervical infection with high-risk HPV, pre-cancerous cell changes and cervical cancer
Antiretroviral therapy (ART) is associated with a lower prevalence of high-risk cervical human papillomavirus (HPV) infection in women with HIV, according to the results of a meta-analysis published in The Lancet HIV. Prevalence of high-grade pre-cancerous HPV-related cervical lesions and invasive cervical cancer was also lower among ART users.
Many people with HIV in the United States are still being diagnosed with HIV late, and therefore not getting the full therapeutic and prevention benefits of starting antiretroviral therapy (ART) early, according to the latest Vital Signs report from the US Centers for Disease Control and Prevention (CDC), released in advance of World AIDS Day.
Children and adolescents are more likely to be tested for HIV if their parents or caregivers are offered a cash incentive, according to the results of a study conducted in Zimbabwe and published in The Lancet HIV. Offering the small cash incentive more than doubled the proportion of children undergoing testing.
Eliminating hepatitis C virus (HCV) as a global public health concern is feasible, but to do this more people need to be tested and treated and prices of direct-acting antivirals (DAAs) need to come down, according to presentations at the AASLD Liver Meeting in Washington, DC.