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TB Alliance Launches Combination Drug Trial, Establishes New Pathway to TB and MDR-TB Treatment

In an ambitious effort to stem the dangerous tide of tuberculosis (TB) and deadly drug-resistant TB around the world, TB Alliance today announced that it has launched a first-of-its-kind Phase II clinical trial to test a novel drug combination – in both patients who have TB, and those who have multidrug-resistant TB (MDR-TB).

Published
20 March 2012
From
TB Alliance
Thibela TB: Community-wide IPT did not improve TB control in South Africa’s mines at the population level

Giving a six- to nine-month course of isoniazid preventive therapy (IPT) at a ‘community-wide level’ – to everyone working at randomly selected South African gold mines –

Published
15 March 2012
By
Theo Smart
SOUTH AFRICA: What the world's largest preventative TB study taught us

Even though the world's largest study of preventative tuberculosis therapy indicated that community-wide isoniazid preventative TB therapy (IPT) failed to lower community TB levels among 27,000 South African gold miners, that was not Thibela’s only result. We review some of the others over its seven years.

Published
13 March 2012
From
IRIN Plus News
Community-level preventive TB therapy in South African gold miners fails to bring down overall incidence

Individuals still saw TB incidence reduction of two-thirds, but effect was not durable Preliminary results from the Thibela Project – which looked at whether community-wide provision of isoniazid preventive therapy (IPT) in South African gold mines would improve TB control in these high-incidence sites.

Published
12 March 2012
From
Science Speaks
SOUTH AFRICA: Preventative TB trial disappoints

After seven years of research, the world's largest study of preventative tuberculosis (TB) therapy has found that untargeted, community-wide distribution of TB prevention drugs did not improve TB control on South African gold mines.

Published
09 March 2012
From
IRIN Plus News
High dose of new HIV drug might improve outcomes for HIV/TB co-infected

A safety and tolerability study lookes at dolutegravir given twice daily with rifampin.

Published
08 March 2012
From
Science Speaks
World Health Organization issues new policy to step up TB/HIV efforts

Around 910,000 lives were saved between 2005 and 2010 as a result of closer working relationships between HIV and TB programmes, according to estimates released today by

Published
02 March 2012
By
Keith Alcorn
WHO launches new policy to boost TB|HIV collaboration

A new updated WHO Policy on collaborative TB/HIV activities was released today. This policy is based on the latest scientific evidence generated from randomized controlled trials and observational studies in the field of TB and HIV, as well as country experiences implementing the previous WHO Interim Policy on collaborative TB/HIV activities published in 2004.

Published
02 March 2012
From
World Health Organization
KENYA: XDR-TB case raises questions

The Kenyan government's recent failure to adequately treat a patient with extensively drug-resistant tuberculosis (XDR-TB) has some civil society organizations questioning whether the country's TB programme is equipped to diagnose and treat such patients.

Published
28 February 2012
From
IRIN PlusNews
EMA Recommends First-Line Anti-TB Drugs for Children

The European Medicines Agency (EMA)'s Committee for Medicinal Products for Human Use (CHMP) agrees with the World Health Organization (WHO) dosing recommendations for ethambutol, isoniazid, pyrazinamide, and rifampicin as first-line antituberculosis medicines used in children, according to new EMA dosing guidelines released February 17.

Published
27 February 2012
From
Medscape (requires free registration)

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Community Consensus Statement on Access to HIV Treatment and its Use for Prevention

Together, we can make it happen

We can end HIV soon if people have equal access to HIV drugs as treatment and as PrEP, and have free choice over whether to take them.

Launched today, the Community Consensus Statement is a basic set of principles aimed at making sure that happens.

The Community Consensus Statement is a joint initiative of AVAC, EATG, MSMGF, GNP+, HIV i-Base, the International HIV/AIDS Alliance, ITPC and NAM/aidsmap
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