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Ambitious new U.S. plan may put hundreds of thousands on MDR-TB treatment

The United States plans to place 360,000 multidrug-resistant tuberculosis patients globally on treatment over the next five years, as part of a national tuberculosis action plan currently under draft.

Published
27 July 2015
From
Science Speaks
Presumptive treatment of TB in advanced HIV no better than giving ART and isoniazid

Giving treatment for tuberculosis to all people with very advanced HIV disease at the time they start antiretroviral therapy, before a laboratory diagnosis of TB –

Published
21 July 2015
By
Keith Alcorn
TAG Pipeline Report

2015 report on the pipeline for new HIV, HCV and TB drugs.

Published
17 July 2015
From
TAG
The Medicines Patent Pool Releases Independent Feasibility Studies on Hepatitis C and Tuberculosis

As part of its ongoing consultation processes on the possibility of the Medicines Patent Pool (MPP) expanding into other disease areas, the organisation has published independent feasibility studies exploring the case for potential entry into Hepatitis C and Tuberculosis.

Published
07 July 2015
From
Medicines Patent Pool
Multidrug-resistant TB appears less transmissible in households than drug-susceptible TB

Some strains of multidrug-resistant tuberculosis (MDRTB) may have a lower fitness (be less capable of spreading) than drug-susceptible tuberculosis bacteria, according to a study published this week in PLOS Medicine.

Published
24 June 2015
From
Eurekalert Inf Dis
Large-scale study underscores value of routine Xpert testing on TB, MDR TB case finding

A study of more than 100,000 patients with suspected tuberculosis at 18 sites across India showed that routine testing using Xpert molecular technology rather than the most commonly used — and oldest — diagnostic tool of examining a sputum smear under a microscope, increased detection of TB by 39 percent and led to five times the rate of detecting resistance to a TB treatment medicine.

Published
28 May 2015
From
Science Speaks
Dust, TB and HIV: the ugly face of mining in South Africa

Two of the greatest philanthropic organisations in the world, responsible for saving countless lives through scientific research and healthcare programmes, are heavily invested in fossil fuel industries that have profound impacts on the health of local communities and cause climate change. Nowhere is this paradox more acute than in South Africa, a country with the biggest HIV caseload in the world and an economy founded on mining.

Published
26 May 2015
From
The Guardian
First all-oral XDR-TB drug regimen trial launches in South Africa

The regimen is comprised of bedaquiline, which received provisional approval from the U.S. Food and Drug Administration in 2013 to treat drug-resistant tuberculosis, pretomanid a new type of antibacterial drug, and linezolid which is used off-label to treat TB.

Published
15 May 2015
From
Science Speaks
WHO moves to improve access to lifesaving medicines for hepatitis C, drug-resistant TB and cancers

WHO today published the new edition of its Model List of Essential Medicines which includes ground-breaking new treatments for hepatitis C, a variety of cancers (including breast cancer and leukaemia) and multi-drug resistant tuberculosis (TB), among others.

Published
11 May 2015
From
World Health Organization
High-dose rifampicin may shorten time to TB clearance

A combination regimen containing high-dose rifampicin (also known as rifampin) was associated with faster tuberculosis (TB) bacteria culture conversion in people with drug-sensitive TB, but moxifloxacin and

Published
13 April 2015
By
Liz Highleyman
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