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The Medicines Patent Pool Releases Independent Feasibility Studies on Hepatitis C and Tuberculosis

As part of its ongoing consultation processes on the possibility of the Medicines Patent Pool (MPP) expanding into other disease areas, the organisation has published independent feasibility studies exploring the case for potential entry into Hepatitis C and Tuberculosis.

Published
7 hours ago
From
Medicines Patent Pool
Multidrug-resistant TB appears less transmissible in households than drug-susceptible TB

Some strains of multidrug-resistant tuberculosis (MDRTB) may have a lower fitness (be less capable of spreading) than drug-susceptible tuberculosis bacteria, according to a study published this week in PLOS Medicine.

Published
24 June 2015
From
Eurekalert Inf Dis
Large-scale study underscores value of routine Xpert testing on TB, MDR TB case finding

A study of more than 100,000 patients with suspected tuberculosis at 18 sites across India showed that routine testing using Xpert molecular technology rather than the most commonly used — and oldest — diagnostic tool of examining a sputum smear under a microscope, increased detection of TB by 39 percent and led to five times the rate of detecting resistance to a TB treatment medicine.

Published
28 May 2015
From
Science Speaks
Dust, TB and HIV: the ugly face of mining in South Africa

Two of the greatest philanthropic organisations in the world, responsible for saving countless lives through scientific research and healthcare programmes, are heavily invested in fossil fuel industries that have profound impacts on the health of local communities and cause climate change. Nowhere is this paradox more acute than in South Africa, a country with the biggest HIV caseload in the world and an economy founded on mining.

Published
26 May 2015
From
The Guardian
First all-oral XDR-TB drug regimen trial launches in South Africa

The regimen is comprised of bedaquiline, which received provisional approval from the U.S. Food and Drug Administration in 2013 to treat drug-resistant tuberculosis, pretomanid a new type of antibacterial drug, and linezolid which is used off-label to treat TB.

Published
15 May 2015
From
Science Speaks
WHO moves to improve access to lifesaving medicines for hepatitis C, drug-resistant TB and cancers

WHO today published the new edition of its Model List of Essential Medicines which includes ground-breaking new treatments for hepatitis C, a variety of cancers (including breast cancer and leukaemia) and multi-drug resistant tuberculosis (TB), among others.

Published
11 May 2015
From
World Health Organization
High-dose rifampicin may shorten time to TB clearance

A combination regimen containing high-dose rifampicin (also known as rifampin) was associated with faster tuberculosis (TB) bacteria culture conversion in people with drug-sensitive TB, but moxifloxacin and

Published
13 April 2015
By
Liz Highleyman
End stigmatizing language in tuberculosis research and practice

Traditional terms invoke metaphors of transgression and punishment rather than of dignity and cure. Phrases such as “treatment defaulter” and “initial defaulter” apply the moral judgment of loan nonpayment to describe patients who stop treatment or never start it. Other phrases, such as “tuberculosis suspect,” treat patients as if they had committed a crime.

Published
07 April 2015
From
EATG / BMJ
Ukraine: Concurrent treatment for HIV/TB co-infection breaks up “deadly alliance”

USAID funded MEASURE Evaluation to initiate an impact evaluation in Ukraine for two TB programmatic priorities: Improving integration of TB and HIV services to reduce mortality through early diagnosis and treatment for co-infected patients; and providing social support services to improve TB treatment adherence.

Published
30 March 2015
From
Science Speaks
Final fight pays off, XXDR-TB & HIV patient cured

Once an active case of extremely drug resistant (XXDR-TB) strain of tuberculosis or totally drug resistant (TDR) TB, 40-year-old Rashid Khan (name changed), has now been completely cured of his disease. Despite having total drug resistance and HIV infection, Khan got cured a few days ago. At one stage he was receiving a cocktail of 18–20 drugs between his HIV and TB regimes. But Bedaquiline made a huge difference in his treatment. He is off medicine now.

Published
24 March 2015
From
DNAIndia
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