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The Road Ahead for HIV Cure Research

Today, with better understanding of the complex task at hand, cure researchers are investigating multiple avenues and taking the long view.

Published
08 January 2019
From
Poz
HIV Establishes Reservoir Within Three Days in Monkeys

Beginning six months of treatment within two days following infection prevented viral rebound in at least some animals in a recent study.

Published
01 January 2019
From
Poz
AIDS - an approach for targeting HIV reservoirs

(Institut Pasteur) Current HIV treatments need to be taken for life by those infected as antiretroviral therapy is unable to eliminate viral reservoirs lurking in immune cells. Institut Pasteur scientists have identified the characteristics of CD4 T lymphocytes that are preferentially infected by the virus. Thanks to metabolic activity inhibitors, the researchers have managed to destroy these infected cells, or 'reservoirs', ex vivo. Their findings were published in the journal Cell Metabolism on Dec. 20, 2018.

Published
20 December 2018
From
Eurekalert Medicine & Health
The HIV/AIDS Activists Transformed Genetic Engineering

Over the past decade, a group of HIV activists has helped pioneer gene therapy.

Published
20 December 2018
From
The Atlantic
Trump quietly shuts down HIV cure research to appease the religious right

Scientists are speaking out against a directive by the Trump administration that has shut down research into a cure for HIV. A scientist who was supposed to supply mice that have been modified with human fetal tissue for an HIV study emailed researchers that the Department of Health and Human Services (HHS) “has directed me to discontinue procuring fetal tissue.”

Published
12 December 2018
From
LGBTQ Nation
UCSF HIV Lab Planning to Close

The facility is the second to have a federal contract involving fetal tissue research cancelled.

Published
06 December 2018
From
The Scientist
Open letter from Chinese HIV professionals on human genome editing

As Chinese professionals engaged in HIV research and prevention, we strongly oppose genome editing on healthy human germline cells and embryos for reproductive purposes and HIV prevention.

Published
05 December 2018
From
The Lancet
Needles in a haystack: the quest for bnAbs

HIV induces antibody responses in infected individuals, but only a few of these individuals manage to produce antibodies that are capable of viral neutralization—and even fewer produce antibodies that can neutralize different strains of HIV.

Published
01 December 2018
From
Nature
Liver transplant from HIV+ living donor to negative recipient: the unanswered questions

A lifesaving partial liver transplant from an HIV-infected mother to her uninfected child – the first of its kind – was conducted last year at the University of the Witwatersrand’s Donald Gordon Medical Centre in Johannesburg. More than a year later, both mother and child are doing well. But the crucial question of the child’s HIV infection status remains unanswered. And we don’t expect to have a definitive answer any time soon.

Published
29 November 2018
From
The Conversation
Gene-Edited Twins in China Still Face Risk of HIV Infection

Certain relatively uncommon strains of HIV would be able to enter their cells if the girls were to come in contact with contaminated tissues or fluids, said Robin Shattock, chairman of mucosal infection and immunity at the U.K.’s Imperial College London.

Published
28 November 2018
From
Bloomberg

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Community Consensus Statement on Access to HIV Treatment and its Use for Prevention

Together, we can make it happen

We can end HIV soon if people have equal access to HIV drugs as treatment and as PrEP, and have free choice over whether to take them.

Launched today, the Community Consensus Statement is a basic set of principles aimed at making sure that happens.

The Community Consensus Statement is a joint initiative of AVAC, EATG, MSMGF, GNP+, HIV i-Base, the International HIV/AIDS Alliance, ITPC and NAM/aidsmap
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This content was checked for accuracy at the time it was written. It may have been superseded by more recent developments. NAM recommends checking whether this is the most current information when making decisions that may affect your health.

NAM’s information is intended to support, rather than replace, consultation with a healthcare professional. Talk to your doctor or another member of your healthcare team for advice tailored to your situation.