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First results of tuberculosis vaccine candidate MTBVAC very promising

A phase I safety study of TB vaccine candidate MTBVAC, the first live-attenuated Mycobacterium  tuberculosis-based vaccine to enter clinical trials, shows very good results in the first intermediate analysis.

Published
18 November 2013
From
TuBerculosis Vaccine Initiative
Researchers see further positive results with herpes virus-based vaccines in monkeys

One of the biggest news stories at the AIDS Vaccine 2013 conference was the groundbreaking experiment in which half of a group of monkeys given a candidate

Published
09 October 2013
By
Gus Cairns
TB vaccine business case: lifesaving TB vaccines feasible

The global tuberculosis (TB) epidemic annually causes 1.4 million deaths and is estimated to cost the global economy €290 billion per year. Vaccines that could prevent people from acquiring, developing and transmitting disease would be the single most effective tool in mitigating this epidemic. Making new TB vaccines available to the world over the next 10-15 years is estimated to cost approximately €600 million, utilizing a highly efficient portfolio approach and adequate funding.

Published
12 June 2013
From
Tuberculosis Vaccine Initiative
Global scientific experts convene in Cape Town to report on progress toward tuberculosis vaccines

At a time of growing global concern about the rising level of drug-resistant strains of tuberculosis in South Africa and worldwide, the world's top TB vaccine experts are meeting this week, the first time this scientific forum has been held in Africa, where they will present new research aimed at advancing development of vaccines against the deadly airborne disease.

Published
25 March 2013
From
Eurekalert Inf Dis
Injection-free vaccination technique could address global vaccine challenge for diseases such as HIV and malaria

Scientists at King’s College London have demonstrated the ability to deliver a dried live vaccine to the skin without a traditional needle, and shown for the first time that this technique is powerful enough to enable specialised immune cells in the skin to kick-start the immunising properties of the vaccine.

Published
11 February 2013
From
Kings College London press release
Results of TB vaccine trial give cause for optimism, say researchers

Results of a trial have been praised for “providing hard evidence about protection against tuberculosis in human beings”. The MVA85A vaccine did not confer any additional protection against

Published
04 February 2013
By
Michael Carter
Data from Historic Phase IIb Clinical Trial for Tuberculosis Vaccine Candidate MVA85A Published in The Lancet

Vaccine candidate did not provide statistically-significant protection in preventing TB disease in infants previously vaccinated with BCG.

Published
04 February 2013
From
Aeras
TB Vaccine Safe but Does Not Confer Protection, Calls for Redoubling Efforts on Global TB Vaccine Portfolio

The clinical trial of the TB vaccine candidate MVA85A was a Phase IIb safety and efficacy trial in 2,797 infants living in the Western Cape province of South Africa. The candidate was safe and well tolerated in the population tested.

Published
04 February 2013
From
Aeras
Revived search for a TB vaccine may be about to pay off

After nearly 100 years, researchers could be on the verge of finding a vaccine that would eradicate tuberculosis infections, a scourge that kills 1.4 million people a year.

Published
04 February 2013
From
Reuters
HEALTH: New TB vaccine on the horizon

A research team at Oxford University in the UK is very close to determining the efficacy of their new tuberculosis (TB) vaccine. If current clinical trials are successful, it will be the first new TB vaccine in almost a century.

Published
17 October 2012
From
IRIN Plus News
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