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An Activist’s Guide to Bedaquiline (Sirturo)

Bedaquiline (also known by its trade name, Sirturo, or as TMC207) is the first new drug from a new drug class to treat TB to be approved by the United States Food and Drug Administration (FDA) in over 40 years. This guide highlights important safety and efficacy data reported thus far and offers advocacy recommendations for activists to take forward. .

Published
12 March 2013
From
Treatment Action Group
Dosing of key TB drug rifampicin could go higher

Rifampicin, a key drug in tuberculosis (TB) treatment, can be tolerated at much higher doses than used in current clinical practice – suggesting that much higher drug

Published
07 March 2013
By
Keith Alcorn
Once-weekly continuation phase TB treatment equals standard of care

A new two-drug combination of rifapentine and moxifloxacin can allow tuberculosis (TB) treatment to be taken once-weekly during the four-month continuation phase, Dr Amina Jindani of St

Published
07 March 2013
By
Keith Alcorn
In India, Fighting TB with Fingerprints

Health specialists in India are using fingerprint technology to make sure tuberculosis sufferers receive proper treatment for the deadly lung infection.

Published
28 February 2013
From
Voice of America
HIV and TB in Practice for nurses: Pregnancy and TB/HIV

This article explains how to prevent and treat TB in pregnant women to protect both mother and child.

Published
14 February 2013
From
HIV & AIDS treatment in practice
HIV and TB in Practice for nurses: Drug-resistant TB

This article summarises the key recommendations on the diagnosis and treatment of drug-resistant TB for nurses, and highlights examples of best practice in their care.

Published
28 January 2013
From
HIV & AIDS treatment in practice
CDC report on U.S. TB drug shortage reflects local and global challenges

According to an article in this week’s Morbidity and Mortality Weekly Report, the 26 health departments handling about 75 percent of the United States tuberculosis caseload have confronted multidrug-resistant tuberculosis, with 21 of those departments — more than 80 percent – facing obstacles to getting the medicine necessary to treat it.

Published
21 January 2013
From
Science Speaks
US Food and Drug Administration approves Sirturo (bedaquiline) to treat MDR TB in adults

The US drug licensing authority has approved the first drug to be developed for multidrug-resistant tuberculosis (MDR TB). Bedaquiline is the first new TB and antimycobacterial drug of any kind to be approved since rifabutin in 1992, and the first new class of drugs for 45 years, since rifampicin in 1967.

Published
02 January 2013
From
FDA
FDA Advisory Committee recommends accelerated approval of bedaquiline for drug-resistant TB

Bedaquiline, the first agent in a new class of TB drug, has been recommended for accelerated approval by the Anti-Infective Drugs Advisory Committee of the United States

Published
03 December 2012
By
Lesley Odendal
HIV and TB in Practice for nurses: Starting ART for treatment and prevention in people with active TB and HIV

This article provides information for nurses on starting HIV treatment for people with HIV and active TB.

Published
29 November 2012
From
HIV & AIDS treatment in practice
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