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Announcement: Updated Guidelines on Managing Drug Interactions in the Treatment of HIV-Related Tuberculosis

The updated guidelines include recommendations for use of newer antiretroviral drugs, including those in new classes, such as CCR5 receptor antagonists and integrase inhibitors. The new guidelines provide additional recommendations regarding use of rifampin with antiretroviral therapy; these recommendations are critical in regions where rifabutin is unavailable.

Published
31 March 2014
From
Morbidity and Mortality Weekly Report
Tuberculosis cases down by 6% but only 1 in 3 MDR TB patients finishes treatment successfully

In 2012, 68 423 cases of tuberculosis (TB) were reported in 29 EU/EEA countries according to new data published by the European Centre for Disease Prevention and Control and the WHO Regional Office for Europe ahead of World Tuberculosis Day.

Published
19 March 2014
From
ECDC
Xpert TB test doesn’t reduce morbidity but it does have important advantages

While it is disappointing that the Xpert did not confer a morbidity or mortality benefit, its advantages include quicker and easier diagnosis with less work for health workers.

Published
10 March 2014
From
HIV i-Base
Rifapentine, moxifloxacin active as part of shorter TB regimen

A shorter treatment regimen consisting of rifapentine, moxifloxacin, isoniazid and pyrazinamide was more active than a control regimen against drug-susceptible pulmonary tuberculosis, researchers reported at the 2014 Conference on Retroviruses and Opportunistic Infections.

Published
10 March 2014
From
Healio
Early ART only increases TB IRIS risk for people with HIV who have a CD4 cell count below 50

A low CD4 cell count increases the risk of immune reconstitution inflammatory syndrome (IRIS) for people starting antiretroviral therapy (ART) within two weeks of treatment for tuberculosis (TB),

Published
28 November 2013
By
Michael Carter
TB treatment must extend beyond the physical body and include social and psychological support as an important aspect of care

Jigna Rao, patient advocate, speaks about patient centered approaches to cure at the TAG symposium “Cascades: Improving TB Care”, held on November 1 during the 2013 Union World Conference on Lung Health in Paris, France.

Published
18 November 2013
From
TB Online
Rifampicin dose can be increased safely in TB treatment, may shorten duration

Increasing the daily dose of rifampicin within the current TB treatment regimen from 10mg/kg to 15mg/kg and 20mg/kg did not result in an increased incidence of adverse events,

Published
13 November 2013
By
Mara Kardas-Nelson
Another negative result in the quest for a shorter TB treatment course

Results from a Phase III trial that attempted to shorten the treatment duration for drug-sensitive pulmonary TB from four to six months, by using gatifloxacin instead of ethambutol,

Published
11 November 2013
By
Mara Kardas-Nelson
Patient-Centered TB Treatment Will Require Modernizing Directly-Observed Therapy

In the first of two linked posts, Mike Frick of Treatment Action Group (TAG) and Audrey Zhang of Harvard College argue that patient-centered approaches in treatment for drug-resistant and drug-sensitive tuberculosis are needed.

Published
31 October 2013
From
PLoS Blogs (blog)
Zero TB declaration by activists

Activists stormed the stage at the World Health Organization (WHO) sponsored Stop TB Symposium during the 44th Union World Conference on Lung Health. TAG's TB Project Director Colleen Daniels called for global action and a new global attitude in the fight against TB.

Published
31 October 2013
From
Treatment Action Group
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