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What does new drug PaMZ mean for TB and HIV treatment?

The development of PaMZ has been hailed as a breakthrough. But what do the experts think?

Published
02 September 2014
From
The Guardian
Acquired rifampicin resistance more likely in HIV-coinfected patients

Patients with HIV and tuberculosis were more likely to develop acquired rifampicin resistance when treated with a thrice-weekly tuberculosis treatment compared with patients not coinfected with HIV, according to researchers from the National Institute for Research in Tuberculosis in India. The rate of bacteriologic failure was 4% among patients without HIV. Among patients with HIV, the rates were 9% for those not receiving ART and 5% for those receiving ART.

Published
02 September 2014
From
Healio
Use of drug susceptibility testing to select therapy improves treatment outcomes in patients with MDR- and XDR-TB

New research published in the online edition of Clinical Infectious Diseases supports World Health Organization (WHO) recommendations for the use of drug susceptibility testing to select drugs for the

Published
13 August 2014
By
Michael Carter
Reduced treatment delays for people with drug-resistant TB and HIV co-infection through decentralised care and rapid Xpert MTB/RIF test

Decentralisation of drug-resistant tuberculosis (DR-TB) management and use of the Xpert MTB/RIF test improves the time from clinic presentation to treatment from 50 days to 7 days

Published
23 July 2014
By
Lesley Odendal
From Rhetoric to Reality: An Analysis of Efforts to Scale Up The Response to TB-HIV

A new research report from ACTION global health shows that joint TB-HIV activities are neglected by HIV programs and overwhelmingly carried out by TB programs, and that global guidelines to address TB-HIV have not been prioritized by leading donors and affected countries.

Published
22 July 2014
From
ACTION
Novel TB regimen could reduce treatment duration

A novel TB drug regimen that could treat drug-sensitive and some forms of drug-resistant TB far more quickly than current standard TB therapy, according to findings from a

Published
21 July 2014
By
Lesley Odendal
HIV, HCV and TB Pipeline Report

Drugs, diagnostics, vaccines, preventive technologies, research towards a cure, and immune-based and gene therapies in development.

Published
21 July 2014
From
Treatment Action Group & i-Base
Apathy in TB fight: The Economist Intelligence Unit

A new report on tuberculosis calls for raising the profile of TB, fight apathy and lack of compelling ambition in addressing the disease.

Published
04 July 2014
From
Stop TB Partnership
An activist's guide to TB drugs

TB treatment must be shorter, simpler, less toxic, and more tolerable and affordable. Activists can contribute to the development and uptake of improved TB treatment by calling attention to research, quality of medications, and access priorities.

Published
04 June 2014
From
TAG
In HIV/TB coinfection, raltegravir may be an alternative to efavirenz

Patients coinfected with HIV and tuberculosis (TB) may benefit from raltegravir as an alternative to efavirenz, new research suggests.

Published
02 June 2014
From
Medscape
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