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Tenofovir resistance may develop in more than half of patients failing treatment in sub-Saharan Africa

More than half of people who experienced failure of a tenofovir-based antiretroviral regimen in sub-Saharan Africa had resistance to tenofovir, a meta-analysis of drug resistance studies published

Published
01 February 2016
By
Keith Alcorn
HIV resistance to favored treatment not uncommon

Resistance to a key HIV drug is common worldwide and could mean trouble for treating and preventing the virus that causes AIDS, according to a new study.

Published
29 January 2016
From
Reuters
Two cases of PrEP failure on solo tenofovir pose significant research questions

A report originally presented to the 2015 BHIVA conference last year details two cases where therapeutic levels of solo tenofovir unequivocally failed to prevent HIV infection in

Published
14 January 2016
By
Gus Cairns
Undetectable & Low-level HIV Viral Replication

Even people who are adherent to their medication regimens may experience occasional “blips” in their viral loads, experience viral rebound or maintain a steady, if low, viral load above undetectable levels. To understand why some people struggle to achieve or remain undetectable, we spoke with Keith Henry, MD, an HIV specialist at Hennepin County Medical Center who has more than 25 years of experience caring for people with HIV.

Published
06 January 2016
From
BETA blog
HIV salvage regimens can safely omit NRTIs, says US study

Nucleoside reverse transcriptase inhibitors (NRTIs) can be safely omitted from HIV salvage therapy, investigators from the United States report in the Annals of Internal Medicine. The findings

Published
04 January 2016
By
Michael Carter
Drug resistance acquired during HIV PrEP rapidly disappears after medication is discontinued

Drug resistance acquired in rare cases of HIV infection during treatment with pre-exposure prophylaxis (PrEP) rapidly disappears once medication is discontinued, investigators report in AIDS. Use of ultra-sensitive tests

Published
14 December 2015
By
Michael Carter
No transmission of integrase inhibitor-resistant HIV seen in California patients

Not one case of transmission of HIV that is resistant to any of the integrase inhibitor (INI) drugs has been seen in newly-diagnosed patients in a database

Published
09 October 2015
By
Gus Cairns
'Super-gonorrhoea' outbreak across north of England sparks national alert

An outbreak of highly drug-resistant gonorrhoea has been detected in the north of England, triggering a national alert. Fifteen cases, all in heterosexuals, have been detected by Public Health England (PHE) so far, the British Association for Sexual Health and HIV said.

Published
18 September 2015
From
Daily Telegraph
Can we ensure adherence to STI treatment guidelines in a world threatened by antimicrobial resistance?

Sexual health care in the UK has traditionally centred on specialist GUM (genito-urinary medicine) services. Since the turn of the twenty-first century primary care has played an increasing role, however. The 2012 Health and Social Care Act is in line with this tendency, with most GP practices now being commissioned to provide level 1 STI screening. Questions have recently been raised about the conformity of care provided by GPs to national guidelines, established for the UK by the British Association for Sexual Health and HIV. In a world where Gonorrhoea – and perhaps one day Chlamydia – is set to become increasingly hard to treat, the problem of ensuring the conformity of generalists to universal standards of treatment is unlikely to go away.

Published
26 August 2015
From
BMJ
Pretreatment HIV drug resistance leads patients to switch to second-line ART

Recent data suggested that retreatment HIV drug resistance in sub-Saharan Africa was associated with a nearly fourfold increase in switching to second-line ART, but did not influence mortality or AIDS-related events.

Published
11 August 2015
From
Healio
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