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Dolutegravir demonstrates good efficacy despite resistance

Antiretroviral regimens containing the recently approved HIV integrase inhibitor dolutegravir (Tivicay) demonstrated high rates of viral suppression even in treatment-experienced people who had virus with resistance to

Published
24 July 2014
By
Liz Highleyman
High rates of drug resistance among HIV-positive infants in South Africa

There was a high prevalence of antiretroviral drug resistance among infants newly diagnosed with HIV in Johannesburg, investigators report in AIDS. Over half the infants

Published
13 July 2014
By
Michael Carter
People starting therapy on a boosted protease inhibitor don't need to switch after one virological failure episode, study indicates

Remaining on the same regimen is a “reasonable” strategy for people taking first-line antiretroviral therapy (ART) based on a ritonavir-boosted protease inhibitor who experience virologic failure, according to

Published
09 June 2014
By
Michael Carter
An activist's guide to TB drugs

TB treatment must be shorter, simpler, less toxic, and more tolerable and affordable. Activists can contribute to the development and uptake of improved TB treatment by calling attention to research, quality of medications, and access priorities.

Published
04 June 2014
From
TAG
No significant risk of resistance if HIV infection occurs during use of Truvada PrEP

Treatment with pre-exposure prophylaxis (PrEP) does not involve a significant risk of HIV drug resistance should seroconversion occur, results from the iPrEx study published in the online edition

Published
13 May 2014
By
Michael Carter
Transmitted HIV Resistance Rate Close to 20% in Large Study of US MSM

More than 17% of antiretroviral-naive men who have sex with men (MSM) in a large US study carried antiretroviral-resistant virus, according to a nationwide analysis by the Centers for Disease Control and Prevention (CDC)]. MSM under 30 years old had close to a 19% prevalence of transmitted resistant HIV.

Published
06 March 2014
From
NATAP
Average CD4 cell count at time HIV therapy was started increased among young people in New York City after 2009

The average CD4 cell count at which young people living with HIV in New York City started antiretroviral therapy increased significantly after US guidelines changed in late

Published
29 January 2014
By
Michael Carter
Successful HIV drug resistance testing is possible when viral load is low

HIV drug resistance testing can perform well, even when viral load is as low as 250 copies/ml, results of two studies published in the online edition of

Published
27 January 2014
By
Michael Carter
Janssen to Stop Offering "Virtual Phenotype" Testing, and Musings on Progress

As is plainly obvious to anyone doing HIV care, the incidence of new patients with the sort of HIV drug resistance for which the test was developed has plummeted. There simply aren't many new patients out there who have multiple mutations, especially in the PI-drug class, and who will need the computational black-box firepower provided by a vircoTYPE.

Published
27 November 2013
From
The BodyPRO
People who aren't taking HIV treatment are a major source of transmitted resistance in Swiss gay men

Individuals who have never taken antiretroviral therapy (ART) are the main source of transmitted HIV drug resistance among gay men, Swiss research published in the online edition of

Published
21 November 2013
By
Michael Carter
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