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Outcomes and prognosis news

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Side-effects
Large study shows the hepatic safety of HIV therapy

Results from a large study published in the online edition of Clinical Infectious Diseases provide reassurance about the hepatic safety of antiretroviral drugs. Investigators from the D:A:D study

Published
22 January 2013
By
Michael Carter
Smoking
Smoking has a bigger impact on the prognosis of HIV-positive patients than HIV-related factors

Much of the increased mortality seen in patients with HIV can be attributed to smoking, Danish investigators report in the online edition of Clinical Infectious Diseases. “The loss

Published
31 December 2012
By
Michael Carter
Outcomes and prognosis
Poor CD4 response to HIV treatment increases risk of death from non-AIDS-related illnesses, even for those with higher baseline counts

A poor increase in CD4 cell count after starting antiretroviral therapy is associated with an increased risk of death due to non-AIDS-related causes, Danish investigators report in

Published
28 December 2012
By
Michael Carter
Outcomes and prognosis
HIV patients in care lose more years of life to smoking than to HIV infection

Among HIV patients receiving well-organized care with free access to antiretroviral therapy, those who smoke lose more years of life to smoking than to HIV, according to a Danish study published in Clinical Infectious Diseases and available online.

Published
21 December 2012
From
EurekAlert
Nutrition
Diet quality predicts HIV progression and death in resource-poor settings

The more diverse and nutrient-rich the diet before starting antiretroviral treatment (ART), the less severe HIV disease progression is, and the less likely death occurs, researchers report in

Published
06 December 2012
By
Carole Leach-Lemens
Outcomes and prognosis
AIDS drug roll-out boosts South African life expectancy

South Africa has achieved a "stunning" increase in life expectancy in the last three years due to a government push to roll out antiretroviral drugs (ARVs) to people with HIV/AIDS, researchers said on Thursday.

Published
01 December 2012
From
Reuters
Women
Low levels of vitamin D associated with poorer long-term CD4 cell gains in women who start HIV treatment late

Vitamin D insufficiency is associated with poorer CD4 cell recovery among women who start HIV treatment late, US investigators report in the online edition of AIDS.

Published
27 November 2012
By
Michael Carter
Treatment guidelines
Abacavir: new studies challenge the evidence of reduced potency when viral load is high

An analysis of two studies of the new HIV integrase inhibitor dolutegravir presented at the Eleventh International Congress on Drug Therapy in HIV Infection in Glasgow had

Published
26 November 2012
By
Gus Cairns
Outcomes and prognosis
Life expectancy in older people with HIV could exceed the average – as long as ART keeps working

The latest forecasts of life expectancy in people with HIV in the UK, based on mortality data from the UK Collaborative HIV Cohort (UK CHIC) study, show

Published
19 November 2012
By
Gus Cairns
Outcomes and prognosis
Death rates elevated at all CD4 counts below 500 in sub-Saharan Africa

A comparison of death rates between the HIV-positive and HIV-negative partners in serodiscordant couples in sub-Saharan Africa has found significantly higher death rates in people with HIV

Published
06 November 2012
By
Keith Alcorn
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