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New and experimental hepatitis C treatment news

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Sofosbuvir/velpatasvir + GS-9857 for 8 weeks cures hepatitis C for most people with genotype 1 or 3

An 8-week triple combination of Gilead Sciences' sofosbuvir, velpatasvir and GS-9857 showed a high sustained response rate in a phase 2 study of people with difficult-to-treat hepatitis

Published
16 November 2015
By
Liz Highleyman
Grazoprevir/elbasvir shows high hepatitis C cure rate for people who inject drugs

Merck's grazoprevir/elbasvir co-formulation cured hepatitis C infection in 92% of people who inject drugs (PWID) who received opioid substitution therapy in the C-EDGE CO-STAR study,

Published
16 November 2015
By
Liz Highleyman
Study suggests unprecedented 3-week hepatitis C cure

Yet another stunning victory in the drug battle against the liver-damaging hepatitis C virus (HCV) may be in the offing: A small study suggests it may be possible to cure some people of their infections in as few as 3 weeks.

Published
02 November 2015
From
Science
Gilead Seeks FDA Approval for Hep C Treatment for All Genotypes

Gilead has applied to the FDA for approval of the combo tablet of Sovaldi and velpatasvir to treat those with genotypes 1 through 6 of hepatitis C.

Published
02 November 2015
From
AIDSMeds
'Dallas Buyers' Club' for Hep C treatments under investigation

A "Dallas Buyers Club" of doctors and patients importing potentially life-saving Hepatitis C medication from countries like China is being investigated by the Therapeutic Goods Administration.

Published
22 October 2015
From
Sydney Morning Herald
NICE Recommends Daklinza (daclatasvir) for Treatment of Certain Patients with Chronic Hepatitis C Genotypes 1, 3 and 4

Bristol-Myers Squibb today announced that the National Institute for Health and Care Excellence (NICE) has recommended Daklinza (daclatasvir) in England and Wales for the treatment of adult patients with chronic hepatitis C virus (HCV) infection. Specifically, NICE recommended Daklinza, an oral, once-daily medication used in combination with other agents, to treat certain patients with HCV genotypes 1, 3 and 4.

Published
16 October 2015
From
Bristol-Myers Squibb press release
U.S. FDA Grants Priority Review For Daklinza (daclatasvir) sNDAs

Three applications are under review for Daklinza in combination with sofosbuvir with or without ribavirin to treat chronic hepatitis C patients with decompensated cirrhosis, post-liver transplant recurrence of HCV, and coinfection with HIV-1.

Published
07 October 2015
From
Bristol-Myers Squibb
Gilead Announces SVR12 Rates from Four Phase 3 Studies Evaluating a Once-Daily, Fixed-Dose Combination of Sofosbuvir (SOF) and Velpatasvir (VEL) (GS-5816) for the Treatment of All Six Hepatitis C Genotypes

If Approved, SOF/VEL Would be the First All-Oral Pan-Genotypic Single Tablet Regimen for Chronic HCV. U.S. NDA and European MAA Submissions Planned for Q4. 2015.

Published
21 September 2015
From
Gilead press release
Achillion Reports 100% SVR12 From Second Cohort of Patients in the Previously-Completed Six Week Phase 2 Trial Evaluating Odalasvir (ACH-3102) and Sofosbuvir for Genotype 1 HCV ("Proxy Study")

100% SVR12 reported for all patients treated for six- (n=18) or eight-weeks (n=12). Odalasvir (ACH-3102) is the subject of an exclusive, worldwide development and commercialization license granted to Janssen

Published
18 September 2015
From
Achillion press release
Updated Label for Daklinza (daclatasvir) for the 12-week Treatment of Non-cirrhotic Patients with Chronic Hepatitis C Genotype 3 Approved by the European Commission

Daklinza in combination with sofosbuvir is the first 12-week all-oral therapy for genotype 3 patients without cirrhosis in Europe.

Published
15 September 2015
From
Bristol-Myers Squibb press release

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