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Women’s bacteria thwarted attempt at anti-HIV vaginal gel

Creating new HIV prevention tools for women has proven frustratingly slow and researchers have found another hurdle: bacteria in the reproductive tract.

Published
02 June 2017
From
STAT
IPM Advances Three-month HIV Prevention and Contraception Ring to Clinical Trial

The three-month vaginal ring is designed to slowly — and simultaneously — release the antiretroviral drug dapivirine to prevent HIV and the contraceptive hormone levonorgestrel. The primary goal of the study, known as MTN-030/IPM 041, is to assess the ring’s safety and pharmacokinetics (how the body processes the two drugs). Results of the trial, including the product’s acceptability to women and their willingness to use it in the future, will inform next steps for the ring’s formulation and future trial designs.

Published
03 May 2017
From
International Partnership for Microbicides
MTN begins first trial of new dapivirine ring with both anti-HIV drug and contraceptive

Researchers hoping for a single product to protect against both HIV and unintended pregnancy took an important step toward realizing their goal with the start of a trial of a vaginal ring containing the antiretroviral drug dapivirine and a hormonal contraceptive. A dapivirine-only ring that women use a month at a time was safe and helped prevent HIV in two large trials. The new ring adds levonorgestrel and could be used for three months.

Published
03 May 2017
From
Eurekalert Medicine & Health
Bacterial vaginosis does not affect efficacy of oral PrEP in women

Research presented at the Conference on Retroviruses and Opportunistic Infections (CROI 2017) found that the efficacy of oral pre-exposure prophylaxis (PrEP) for women was not affected

Published
23 February 2017
By
Gus Cairns
Vaginal Ring Form of PrEP Does Not Reduce Contraceptive Effectiveness

The antiretroviral (ARV)-containing vaginal ring form of pre-exposure prophylaxis (PrEP) that reduced HIV risk in a major trial does not lower the effectiveness of hormonal birth control. This finding assuages concerns raised by previous research that the non-nucleoside reverse transcriptase inhibitor (NNRTI) class of ARVs has been associated with a lowered effectiveness of some hormonal contraceptives.

Published
16 February 2017
From
Poz
New HIV prevention products will need marketing and effective health services to reach the people who need them

There is a naivety among many HIV prevention researchers and advocates about the steps needed to introduce and implement new HIV prevention technologies such as oral pre-exposure

Published
24 October 2016
By
Roger Pebody
New microbicide enema achieves high levels of drug in rectal tissues in monkeys

Rectal microbicides that protect against HIV transmission via anal sex are a bigger technical challenge than vaginal ones. The rectal lining is more delicate than the vaginal, so

Published
22 October 2016
By
Gus Cairns
Rings, films or inserts? Researchers need to develop prevention products that make sense in women’s lives

“We need to think outside of the box,” Sharon Hillier of the Microbicide Trials Network told the HIV Research for Prevention (HIVR4P 2016) conference in Chicago

Published
21 October 2016
By
Roger Pebody
Vaginal and rectal bacteria may have a big influence on HIV transmission and microbicide efficacy

A number of presentations at the 2016 HIV Research for Prevention Conference (HIVR4P) in Chicago looked at the influence vaginal bacteria have on HIV susceptibility, and one

Published
20 October 2016
By
Gus Cairns
London gay men anticipate some pros and cons of different PrEP methods – but optimal efficacy is key to acceptability

When presented with a range of possible HIV prevention technologies – a daily pill, pills before and after sex, injections, or a rectal gel – gay men

Published
09 September 2016
By
Roger Pebody
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Community Consensus Statement on Access to HIV Treatment and its Use for Prevention

Together, we can make it happen

We can end HIV soon if people have equal access to HIV drugs as treatment and as PrEP, and have free choice over whether to take them.

Launched today, the Community Consensus Statement is a basic set of principles aimed at making sure that happens.

The Community Consensus Statement is a joint initiative of AVAC, EATG, MSMGF, GNP+, HIV i-Base, the International HIV/AIDS Alliance, ITPC and NAM/aidsmap
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This content was checked for accuracy at the time it was written. It may have been superseded by more recent developments. NAM recommends checking whether this is the most current information when making decisions that may affect your health.

NAM’s information is intended to support, rather than replace, consultation with a healthcare professional. Talk to your doctor or another member of your healthcare team for advice tailored to your situation.