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Kidney problems news

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New and experimental HIV treatments
New pro-drug tenofovir alafenamide appears equally effective but better tolerated

Tenofovir alafenamide fumarate or TAF (formerly GS-7340), a new pro-drug of the widely used NRTI tenofovir, reaches cells harbouring HIV more easily than the older tenofovir disoproxil

Published
07 March 2013
By
Liz Highleyman
Kidney problems
Tenofovir, atazanavir/ritonavir and Kaletra associated with kidney problems in patients taking HIV therapy

Data from a large study into the safety of anti-HIV drugs suggest that the antiretrovirals tenofovir (Viread, also in Truvada, Atripla and Eviplera), atazanavir (Reyataz) and lopinavir/ritonavir

Published
15 February 2013
By
Michael Carter
Kidney problems
Tenofovir May Raise Risk of Kidney Damage, but Effect Tapers Over Time

Tenofovir raises the risk of kidney dysfunction among people with HIV, but the adverse effect occurs mostly within the first two years of therapy.  

Published
14 February 2013
From
AIDSMeds
Kidney problems
Kidney disease in HIV-Infected Patients: Guideline and Commentary

The New York State Department of Health AIDS Institute has issued timely new guidelines on kidney disease in HIV-infected adults. Key points emphasize the importance of informing and educating HIV-infected patients about the increased risk for kidney disease; routinely assessing kidney function in HIV-infected patients; recommending earlier antiretroviral therapy (ART) initiation to patients with HIV-associated nephropathy; and assessing ART medication dosages, as well as other medications, when a patient's GFR reaches ≤ 50 mL/min.

Published
17 October 2012
From
Medscape (requires registration)
Health problems
More HIV-Positive Patients Receive Organ Transplants

Hospitals are increasingly willing to transplant vital and scarce organs into people who have HIV, a once-unthinkable step now made possible with drug regimens that are helping such patients live longer.

Published
12 October 2012
From
Wall Street Journal
Nutrition
Obesity is a risk factor for co-occuring chronic health problems in patients with HIV

Obesity is associated with the clustering of multiple health problems in HIV-positive people, investigators from the US report in the online edition of the Journal of Acquired Immune

Published
10 October 2012
By
Michael Carter
Health problems
Starting HIV treatment reduces the risk of serious non-AIDS-related diseases

Serious non-AIDS-defining illnesses are common in people recently diagnosed with HIV, Spanish investigators report in the online edition of AIDS. “Clinicians should be aware that during the initial

Published
09 October 2012
By
Michael Carter
New and experimental HIV treatments
Integrated analysis shows 'Quad' pill has potent activity with fewer side-effects

An integrated analysis of data from phase II and III trials showed that the 'Quad' single-tablet regimen has antiviral efficacy at least as good as comparison regimens

Published
12 September 2012
By
Liz Highleyman
Hepatitis C
Chronic hepatitis C virus infection increases risk of death from both liver disease and non-liver-related causes

As well as increasing the risk of death from liver disease, chronic hepatitis C virus infection increased the risk of death from circulatory and kidney disease

Published
05 September 2012
By
Michael Carter
Kidney problems
Atazanavir/ritonavir more likely to cause kidney stones than other ritonavir-boosted protease inhibitors

Treatment with ritonavir-boosted atazanavir is associated with a much higher risk of kidney stones compared to other ritonavir-boosted protease inhibitors, Japanese investigators report in the online edition of

Published
29 August 2012
By
Michael Carter
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