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A question of timing: A lawsuit claims Gilead Sciences could have developed a less-harmful version of its HIV treatment sooner

More than a decade ago, researchers at Gilead Sciences thought they had a breakthrough: a new version of the company’s key HIV medicine that was less toxic to kidneys and bones. But in 2004 Gilead executives stopped the research, only to restart it as the expiration of tenofovir’s patent in 2018 neared.

Published
3 hours ago
From
Los Angeles Times
HIV-infected organs transplanted at Birmingham hospital

A Birmingham hospital has successfully transplanted two HIV infected organs into patients also suffering from the disease. Liver transplants, from two separate donors, were carried out at the Queen Elizabeth Hospital, in Edgbaston, in the pioneering procedures. Whilst one patient donated both kidneys in surgery performed at Guy’s Hospital, in London.

Published
19 May 2016
From
Birmingham Mail
In a first, liver and kidney from HIV-infected donor are transplanted into HIV-positive patients

In a first that gives HIV-positive patients yet another chance for long lives, surgeons at Johns Hopkins University Medical Center have transplanted a kidney and a liver from a deceased donor who was positive for HIV into two HIV-positive recipients.

Published
31 March 2016
From
Los Angeles Times
Modest kidney function decline in people taking Truvada for PrEP supports need for monitoring

Participants taking tenofovir/emtricitabine (Truvada) for pre-exposure prophylaxis (PrEP) in two major studies experienced modest declines in kidney function that were associated with higher tenofovir drug levels and older

Published
02 March 2016
By
Liz Highleyman
TAF/emtricitabine maintains viral suppression as well as TDF regimens with less bone and kidney toxicity

A fixed-dose coformulation of tenofovir alafenamide (TAF) and emtricitabine (FTC, Emtriva), combined with a variety of third antiretroviral agents, maintained undetectable viral load in people who switched

Published
25 February 2016
By
Liz Highleyman
Direct-acting antivirals reduce cryoglobulinemia in hepatitis C

Treatment with direct-acting antivirals not only cures people of hepatitis C, but can also rapidly reduce the severity of one of the most troublesome extrahepatic manifestations of

Published
19 February 2016
By
Keith Alcorn
Survival and outcome analysis shows that selected HIV-positive patients are good candidates for liver and kidney transplant

Liver and kidney transplant can be justified for carefully selected HIV-positive patients, researchers from the United States show in AIDS. Transplant improved the chances of survival for HIV-positive

Published
11 February 2016
By
Michael Carter
Johns Hopkins approved to perform first HIV-positive to HIV-positive organ transplants in U.S.

Johns Hopkins recently received approval from the United Network for Organ Sharing to be the first hospital in the United States to perform HIV-positive to HIV-positive organ transplants. The institution will be the first in the nation to do an HIV-positive kidney transplant and the first in the world to execute an HIV-positive liver transplant.

Published
09 February 2016
From
Johns Hopkins Medicine
Two-drug maintenance therapy keeps viral load suppressed and may even have advantages over traditional ART

Two-drug antiretroviral therapy (ART) consisting of ritonavir-boosted atazanavir and lamivudine has comparable or better virological efficacy than traditional three-drug therapy based on ritonavir/atazanavir, according to a poster presentation at

Published
30 November 2015
By
Michael Carter
NIH publishes criteria for research on organ transplantation between people with HIV infection

​In a Federal Register notice on Nov. 25, 2015, the U.S. Department of Health and Human Services published safeguards and criteria for research to assess the safety and effectiveness of solid organ transplantation from donors with HIV infection to recipients with HIV infection.

Published
27 November 2015
From
National Institutes of Health
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