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Switching to new tenofovir alafenamide keeps virus in check and improves kidney and bone health

People who switch from the current version of tenofovir to tenofovir alafenamide (TAF) – a new formulation that reaches higher levels in HIV-infected cells – maintained undetectable

Published
28 July 2015
By
Liz Highleyman
Geriatric HIV: living with multiple medical conditions will become the norm as population ages

In fifteen years' time, the clinical needs of Dutch people living with HIV will have changed substantially due to three quarters of them being over the

Published
16 June 2015
By
Roger Pebody
Lower daily tenofovir dose of 150mg safe and effective in people with moderate renal impairment

A reduced tenofovir (Viread) dose of 150mg daily appears to be a safe and effective treatment for people with HIV who have moderate renal impairment, investigators from

Published
22 May 2015
By
Michael Carter
HHS Establishes Organ Donation Policy for Patients With HIV

The US Department of Health and Human Services (HHS) has unveiled new regulations to establish a parallel system of organ donation intended to serve patients with the human immunodeficiency virus (HIV).

Published
11 May 2015
From
Regulatory Affairs Professionals Society
HIV Patients May Fare as Well as Others With Kidney Transplants

Kidney transplant patients with HIV have similar survival rates as those without HIV, a new study finds. The study included 510 HIV-positive adults who had kidney transplants in the United States between 2002 and 2011. Overall, these patients had similar five- and 10-year survival rates as kidney transplant patients without HIV.

Published
20 March 2015
From
U.S. News & World Report
Tenofovir, boosted atazanavir and boosted lopinavir are associated with cumulative risk of developing chronic kidney disease

Three antiretroviral drugs are associated with a slowly increasing rate of chronic kidney disease over time, the Conference on Retroviruses and Opportunistic Infections (CROI 2015) in

Published
27 February 2015
By
Gus Cairns
Patients with HIV can safely receive kidneys from deceased HIV-positive donors, with good five-year survival rates

HIV-positive patients can safely receive kidneys from deceased HIV-infected donors, investigators from South Africa report in the February 12th edition of the New England Journal of Medicine. 

Published
16 February 2015
By
Michael Carter
Tenofovir-based HIV PrEP does not harm kidneys

Men and women without HIV infection who use tenofovir-based pre-exposure prophylaxis (PrEP) develop significant but not clinically relevant declines in kidney function, according to the largest study to date to look at the issue.

Published
26 December 2014
From
Medscape (requires free registration)
HIV-infected adults diagnosed with age-related diseases at similar ages as uninfected adults

HIV-infected adults are at a higher risk for developing heart attacks, kidney failure and cancer. But, contrary to what many had believed, the researchers say these illnesses are occurring at similar ages as adults who are not infected with HIV.

Published
10 December 2014
From
Science Daily
IDWeek 2014: Longer Use, Age, Low Body Weight Raise Risk of Tenofovir Kidney Problems

Abnormal kidney biomarkers are common but rarely progress to serious kidney dysfunction in HIV positive people taking tenofovir, and longer duration of use, older age, and having diabetes or high blood pressure raise the risk, researchers reported at IDWeek 2014 last week in Philadelphia. A related study found that people with low body weight experienced progressive kidney function decline while taking tenofovir.

Published
20 October 2014
From
HIVandhepatitis.com
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