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IDWeek 2014: Longer Use, Age, Low Body Weight Raise Risk of Tenofovir Kidney Problems

Abnormal kidney biomarkers are common but rarely progress to serious kidney dysfunction in HIV positive people taking tenofovir, and longer duration of use, older age, and having diabetes or high blood pressure raise the risk, researchers reported at IDWeek 2014 last week in Philadelphia. A related study found that people with low body weight experienced progressive kidney function decline while taking tenofovir.

Published
20 October 2014
From
HIVandhepatitis.com
Gilead Sciences: A Preview of Important HIV Drug Study Results

Gilead is running nine phase III studies involving tenofovir alafenamide (TAF), which reflects the importance of the drug to Gilead's future HIV business. It is collecting an enormous amount of clinical data in which to make the case that TAF should be a preferred backbone drug for new and existing HIV patients, as well as patients who cannot use Viread because of pre-existing kidney conditions.

Published
23 September 2014
From
The Street
Guidelines Advise Against Tenofovir for HIV Patients With Kidney Disease

HIV-positive patients who have reduced kidney function should take antiretroviral therapy, but should avoid regimens that contain tenofovir (Viread), according to updated treatment guidelines from the HIV Medicine Association (HIVMA).

Published
22 September 2014
From
The Body Pro
Study Dampens HOPE of HIV Organ Donations

The HIV Organ Policy Equity (HOPE) Act, which legalizes research into organ tranplants from HIV-positive donors to HIV-positive recipients, is less than a year old, but a new study already suggests the organs may be of poor quality.

Published
17 September 2014
From
Medscape (requires registration)
Tenofovir HIV PrEP causes no long-term harm to kidneys

HIV pre-exposure prophylaxis (PrEP) with tenofovir is associated with mild disturbances in kidney function that resolve when treatment is stopped, investigators report in the online edition of Clinical

Published
21 May 2014
By
Michael Carter
Risk score can help predict which people living with HIV have highest risk of kidney disease during tenofovir treatment

Investigators in the United States have developed a risk score to predict which people living with HIV have the highest risk of developing chronic kidney disease.

Published
31 March 2014
By
Michael Carter
Heart attack link to abacavir persists in D:A:D study

The nucleoside (NRTI) drug abacavir (Ziagen also in Kivexa/Epzicom) continues to be associated with a near-doubling of the risk of a heart attack, according to the latest

Published
14 March 2014
By
Gus Cairns
Why This Man Was Refused a New Lung

People with HIV are still excluded from some life-saving organ transplants, based on guidelines that omit the most current science.

Published
17 February 2014
From
The Atlantic
ART use not linked to advanced kidney disease in 35,000 with HIV

Neither current nor recent use of tenofovir or any other antiretroviral therapy (ART) predicted advanced chronic kidney disease (CKD) or end-stage renal disease (ESRD) in a study or more than 35,000 adults with HIV infection.

Published
12 February 2014
From
International AIDS Society
US: Activists rally for equal access to transplants for patients with HIV

Family and friends of a 29-year-old man who died after being refused a lung transplant call hospital policies unjust

Published
20 December 2013
From
Al Jazeera America
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